Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ravi Jotwani"'
Autor:
Jieun Shin, Kavita B. Hosur, Kalyani Pyaram, Ravi Jotwani, Shuang Liang, Triantafyllos Chavakis, George Hajishengallis
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
Developmental endothelial locus-1 (Del-1) is an endothelial cell-secreted protein that limits the recruitment of neutrophils by antagonizing the interaction between the LFA-1 integrin on neutrophils and the intercellular adhesion molecule (ICAM)-1 on
Externí odkaz:
https://doaj.org/article/0f2c208c0fd7462b932c883b1e0f3be9
Autor:
Robert S. Orefice, Kevin Gillespie, Harry R. Fair, Stephen V. Kosonocky, Donald A. Priore, Samuel D. Naffziger, Sanjay Pant, Kathryn Wilcox, Ravinder Rachala, Jonathan White, Robert Cole, Benjamin Munger, Carson Henrion, Aaron Grenat, Ravi Jotwani
Publikováno v:
IEEE Journal of Solid-State Circuits. 50:24-34
This work describes the physical design implementation of the AMD “Steamroller” module and adaptive clocking system that are both integral pieces of the AMD Kaveri APU SoC which was implemented using a 28 nm high-K metal gate Bulk CMOS process. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c49bdec1a85ea319a6842db8dc6961
https://doi.org/10.1109/jssc.2014.2357428
https://doi.org/10.1109/jssc.2014.2357428
Autor:
Joshua A. Bell, Teja Singh, Stephen V. Kosonocky, Sundar Rangarajan, Shane Southard, Carson Henrion, Hugh McIntyre, Ravi Jotwani, Edward Chang, Amy Novak, Alex Schaefer, Deepesh John, Michael Co
Publikováno v:
ISSCC
Codenamed “Zen”, AMD's next-generation, high-performance ×86 core targets server, desktop, and mobile client applications. Utilizing Global Foundries' energy-efficient 14nm LPP FinFET process, the 44mm2 Zen core complex unit (CCX) has 1.4B trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1531050832f06532f78b6846da5e7c8
https://doi.org/10.1109/isscc.2017.7870256
https://doi.org/10.1109/isscc.2017.7870256
Autor:
Ravi Jotwani, Himabindu Vuddaraju, Shuang Liang, Huizhi Wang, Huaxin Zhou, Xiaoxian Duan, Richard J. Lamont, David A. Scott
Publikováno v:
Infection and Immunity. 82:4118-4126
Pathogen-induced reactive oxygen species (ROS) play a crucial role in host innate immune responses through regulating the quality and quantity of inflammatory mediators. However, the underlying molecular mechanisms of this effect have yet to be clari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20664ade48c18dfada935ab8e6a851f
https://doi.org/10.1128/iai.02000-14
https://doi.org/10.1128/iai.02000-14
Autor:
Ravi Jotwani, Susan Coventry, Silvia M. Uriarte, Jan Potempa, Qian Wang, Jennifer L. Krauss, Richard J. Lamont, Junyi Le
Publikováno v:
Infection and Immunity. 82:1205-1212
Recent microbiome studies have implicated a role for Filifactor alocis in periodontal disease. In this study, we investigated the colonization and survival properties of F. alocis in a mouse subcutaneous chamber model of infection and characterized h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16a5d508e5632142c121b6c3792df2f
https://doi.org/10.1128/iai.01434-13
https://doi.org/10.1128/iai.01434-13
The Role of JAK-3 in Regulating TLR-Mediated Inflammatory Cytokine Production in Innate Immune Cells
Autor:
Huaxin Zhou, Jill Suttles, Jonathan Brown, Shegan Gao, David A. Scott, Shuang Liang, Ravi Jotwani, Richard J. Lamont, Huizhi Wang
Publikováno v:
The Journal of Immunology. 191:1164-1174
The role of JAK-3 in TLR-mediated innate immune responses is poorly understood, although the suppressive function of JAK3 inhibition in adaptive immune response has been well studied. In this study, we found that JAK3 inhibition enhanced TLR-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab8781e05ef2441463fd7c35b2166956
https://doi.org/10.4049/jimmunol.1203084
https://doi.org/10.4049/jimmunol.1203084
The complement system plays a central role in immunity and inflammation, although certain pathogens can exploit complement to undermine protective immunity. In this context, the periodontal keystone pathogen Porphyromonas gingivalis was previously sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1bf3b3dc552e021036e45ee6de6f2e
https://europepmc.org/articles/PMC5065733/
https://europepmc.org/articles/PMC5065733/
Autor:
Megan L. McIntosh, Mark A. Payne, Ahmed Hashim, John D. Lambris, Ravi Jotwani, Richard P. Darveau, Michael A. Curtis, Mehmet A. Eskan, Asil Alsam, George Hajishengallis, Shuang Liang, Keith L. Kirkwood
Publikováno v:
Cell Host & Microbe. 10(5):497-506
Porphyromonas gingivalis is a low-abundance oral anaerobic bacterium implicated in periodontitis, a polymicrobial inflammatory disease, and the associated systemic conditions. However, the mechanism by which P. gingivalis contributes to inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bbc0b4d0d36640f28baf4727e8ccde
Autor:
Stephen V. Kosonocky, Sriram Sundaram, Victor F. Andrade, Amy Novak, Ravi Jotwani, Alexander W. Schaefer, Samuel D. Naffziger
Publikováno v:
IEEE Journal of Solid-State Circuits. 46:162-172
This paper describes the 32 nm implementation of an AMD x86-64 core. It occupies 9.69 mm2, contains more than 35 million transistors (excluding L2 cache), and operates at frequencies in excess of 3 GHz. This AMD chip is fabricated in Global Foundries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8862f6d5bca4d9522dfad0c2ac7cec92
https://doi.org/10.1109/jssc.2010.2080530
https://doi.org/10.1109/jssc.2010.2080530
Autor:
Surinder S Moonga, Ravi Jotwani, Christopher W. Cutler, Sridhar Veerkeralam Kuppusamy Eswaran
Publikováno v:
FEMS Immunology & Medical Microbiology. 58:314-321
Matrix metalloproteinase-9 (MMP-9) cleaves collagen, allowing leukocytes to traffic toward the vasculature and the lymphatics. When MMP-9 is unregulated by tissue inhibitor of metalloproteinase-1 (TIMP-1), this can lead to tissue destruction. Dendrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb97a361d014631522ddb1ce27e0675a
https://doi.org/10.1111/j.1574-695x.2009.00637.x
https://doi.org/10.1111/j.1574-695x.2009.00637.x