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pro vyhledávání: '"Ravi Chandra Dubey"'
Autor:
Nisha Vats, Ravi Chandra Dubey, Madhusudana Girija Sanal, Pankaj Taneja, Senthil Kumar Venugopal
Publikováno v:
F1000Research, Vol 9 (2020)
Background: Bile salt export pump (BSEP/ABCB11) is important in the maintenance of the enterohepatic circulation of bile acids and drugs. Drugs such as rifampicin and glibenclamide inhibit BSEP. Progressive familial intrahepatic cholestasis type-2, a
Externí odkaz:
https://doaj.org/article/a67d30726a2e40dd946a2e45133ae7fc
Publikováno v:
Journal of Medical Virology. 93:6377-6382
Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectl
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2/2019-nCoV) infection is an emerging pandemic. The virus binds to angiotensin converting enzyme 2 (ACE2) and TMPRSS2 which are abundantly expressed on various human cells including lung epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e666aa53fb0c7114a871a41984ec62b4
https://doi.org/10.20944/preprints202004.0153.v1
https://doi.org/10.20944/preprints202004.0153.v1
Autor:
Ravi Chandra Dubey, Abhi Bhattarai, Dibya Ghimire, Laxmi Prasad Adhikari, Ritu Gaur, Uddhav Timilsina, Madhu Rai, Nawneet Mishra
Publikováno v:
Virology. 521:44-50
HIV-1 Maturation inhibitors (MIs) bind to the C-terminal domain of capsid protein (CA-CTD) and spacer peptide 1 (SP1) in HIV-1 Gag and inhibit the CA-SP1 cleavage by stabilizing the immature Gag. The β-turn motif, GVGGP in the HIV CA-CTD (residues 2
Publikováno v:
Biochemical and Biophysical Research Communications. 482:713-719
Mitochondrial Dysfunction has been implicated in multiple human diseases, including cancer. Among all cancer, lung cancer is the most common type of cancer worldwide with low survival rates. Mammals possess multiple subunits of the mitochondrial enzy
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
The high genetic diversity of Human Immunodeficiency virus (HIV), has hindered the development of effective vaccines or antiviral drugs against it. Hence, there is a continuous need for identification of new antiviral targets. HIV exploits specific h