Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ravi Malaviya"'
Autor:
Ravi Malaviya, Zhao Zhou, Holly Raymond, Josh Wertheimer, Brian Jones, Rachel Bunting, Patrick Wilkinson, Lohith Madireddy, LeRoy Hall, Mary Ryan, Tadimeti S. Rao
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract We conducted a systematic evaluation of lung inflammation indued by repeated intranasal exposure (for 10 consecutive days) to a human aeroallergen, house dust mite (HDM) in BALB/c mice. Peak influx of neutrophils, monocytes/lymphocytes, and
Externí odkaz:
https://doaj.org/article/a295a7bb64c046f38c109f40818b9c6f
Autor:
Songmao Zheng, Fang Shen, Brian Jones, Damien Fink, Brian Geist, Ivo Nnane, Zhao Zhou, Jeff Hall, Ravi Malaviya, Tatiana Ort, Weirong Wang
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Tumor necrosis factor (TNF) and interleukin (IL)-17A are pleiotropic cytokines implicated in the pathogenesis of several autoimmune diseases including rheumatoid arthritis (RA) and psoriatic arthritis (PsA). JNJ-61178104 is a novel human anti-TNF and
Externí odkaz:
https://doaj.org/article/14de5e65d91743cea20438bf02341a93
Autor:
Pooja Ravi Malaviya, Harsha Jariwala
This study aims to identify the determinants of financial socialization of young college going students of Gujarat state located in India. Financial socialization plays a pivotal role in developing financial attitude of the youngsters which motivates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342149d53f24b0bf8a2523ee955a0cd7
Autor:
Chunxu Gao, Shannon Hitchcock, Ravi Malaviya, Tadimeti S. Rao, Heather Deutsch, Chidozie Amuzie, Matteo Cesaroni, Debra Gardner, Davit Sargsyan, Marie-Clare Theobalds
Publikováno v:
Clin Exp Immunol
Graft versus host disease (GvHD) is a major clinical problem with a significant unmet medical need. We examined the role of cytotoxic T lymphocyte antigen-4 (CTLA-4) in a xenogenic GvHD (xeno-GvHD) model induced by injection of human peripheral monon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec5d49093f27c69c2b8b00692e2280f
https://doi.org/10.1111/cei.13659
https://doi.org/10.1111/cei.13659
Autor:
Josh Wertheimer, Mary Ryan, Patrick Wilkinson, Tadimeti S. Rao, Brian Jones, Ravi Malaviya, LeRoy Hall, Holly Raymond, Lohith Madireddy, Zhao Zhou, Rachel Bunting
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
We conducted a systematic evaluation of lung inflammation indued by repeated intranasal exposure (for 10 consecutive days) to a human aeroallergen, house dust mite (HDM) in BALB/c mice. Peak influx of neutrophils, monocytes/lymphocytes, and eosinophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f08918a5e6fde5df2902cded4b267d6
https://doaj.org/article/a295a7bb64c046f38c109f40818b9c6f
https://doaj.org/article/a295a7bb64c046f38c109f40818b9c6f
Autor:
Kristi A. Leonard, Kevin D. Kreutter, Suzie Kim, Tadimeti S. Rao, Michael C. Harris, Wenying Chai, Tatiana Koudriakova, Paul J. Krawczuk, Russell C. Smith, James P. Edwards, Mark Seierstad, Marguerite E. Johnson, Lisa Madge, Jennifer D. Venable, Gavin C. Hirst, Genesis M. Bacani, Aihua Wang, Ravi Malaviya, Mark S. Tichenor, Michele C. Rizzolio, Ashok S. Mathur
Publikováno v:
Journal of medicinal chemistry. 63(6)
To identify Janus kinase (JAK) inhibitors that selectively target gastrointestinal tissues with limited systemic exposures, a class of imidazopyrrolopyridines with a range of physical properties was prepared and evaluated. We identified compounds wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c7f6dc6bca7939f0adbd0515e0e729
https://pubmed.ncbi.nlm.nih.gov/32134643
https://pubmed.ncbi.nlm.nih.gov/32134643
Publikováno v:
Journal of visualized experiments : JoVE. (152)
Profiling molecular changes in local tissues is crucial to understand the mechanism(s) of action of therapeutic candidates in vivo. In the field of arthritis research, many studies are focused on inflamed joints that are composed of a complex mixture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98075129c1fcbd86d47194df3d532469
https://pubmed.ncbi.nlm.nih.gov/31736486
https://pubmed.ncbi.nlm.nih.gov/31736486
Autor:
A. Richard Kitching, Hendrik J. Nel, Jamie Rossjohn, Ryan Galea, Yi Tian Ting, Sara Hadjigol, Ben J. Boyd, Loui Madakamutil, Hugh H. Reid, Ranjeny Thomas, Megan Huynh, Xiao Liu, Joshua D. Ooi, Natalie Goh, Suzanne Cole, Ravi Malaviya, Kate J. Robson, Suman Yekollu, Martine Boks, Daniel Baker, Bijun Zeng, Karyn Cochlin, Brendan O'Sullivan, Meghna Talekar, Shannon Hitchcock, Helen Roberts, David Shealy
Publikováno v:
Nature reviews. RheumatologyOriginal article. 15(12)
Autoimmune diseases resulting from MHC class II–restricted autoantigen-specific T cell immunity include the systemic inflammatory autoimmune conditions rheumatoid arthritis and vasculitis. While currently treated with broad-acting immunosuppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc47b75f76cda7699c9976f3aaab335
https://pubmed.ncbi.nlm.nih.gov/31487265
https://pubmed.ncbi.nlm.nih.gov/31487265
Autor:
Matthew J. Loza, Brian Jones, Daniel Weinstock, Amy Volk, Akash H. Verma, Fang Shen, Sarah L. Gaffen, Bianca M. Coleman, Beverley A. Moore, M. Merle Elloso, Ravi Malaviya, Tatiana Ort
The cytokines TNF-α and IL-17A are elevated in a variety of autoimmune diseases, including rheumatoid arthritis. Both cytokines are targets of several biologic drugs used in the clinic, but unfortunately many patients are refractory to these therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4d14046ea45629e37459dd58141e4e
https://europepmc.org/articles/PMC6424616/
https://europepmc.org/articles/PMC6424616/
Mast cells are well known for their harmful role in IgE-mediated hypersensitivity reactions, but their physiological role remains a mystery. Several recent studies have reported that mast cells play a critical role in innate immunity in mice by relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab784d057ff53e0e22d4aae4f1a010b0
https://ora.ox.ac.uk/objects/uuid:c2af9c10-f429-46bc-b05d-e236c31339a9
https://ora.ox.ac.uk/objects/uuid:c2af9c10-f429-46bc-b05d-e236c31339a9