CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway

Autor: Deleye, Y. (Yann), Karen Cotte, A. (Alexia), Hannou, S. (Sarah), Hennuyer, N. (Nathalie), Bernard, L. (Lucie), Derudas, B. (Bruno), Caron, S. (Sandrine), Legry, V. (Vanessa), Vallez, E. (Emmanuelle), Dorchies, E. (Emilie), Martin, N. (Nathalie), Lancel, S. (Steve), Annicotte, J. (Jean), Bantubungi, K. (Kadiombo), Pourtier, A. (Albin), Raverdy, V. (Violeta), Pattou, F. (François), Lefebvre, P. (Philippe), Abbadie, C. (Corinne), Staels, B. (Bart), Haas, J. (Joel), Paumelle, R. (Réjane)

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 295 (50), pp.17310-17322. ⟨10.1074/jbc.RA120.012543⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295, pp.17310-17322. ⟨10.1074/jbc.RA120.012543⟩
Journal of Biological Chemistry, 2021, 295 (50), pp.17310-17322. ⟨10.1074/jbc.RA120.012543⟩
J Biol Chem

International audience; In addition to their well-known role in the control of cellular proliferation and cancer, cell cycle regulators are increasingly identified as important metabolic modulators. Several GWAS have identified SNPs near CDKN2A, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cfbc22f71317db0690865ca85cfde0cd
https://www.hal.inserm.fr/inserm-03019831v2/document