In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary Investigation

Autor: Waryah, C.B., Wells, K., Ulluwishewa, D., Chen-Tan, N., Gogoi-Tiwari, J., Ravensdale, J., Costantino, P., Gokcen, A., Vilcinskas, A., Wiesner, J., Mukkur, T.

Staphylococcus aureus in biofilms is highly resistant to the treatment with antibiotics, to which the planktonic cells are susceptible. This is likely to be due to the biofilm creating a protective barrier that prevents antibiotics from accessing the

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https://publica.fraunhofer.de/handle/publica/251876

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In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary Investigation.

Autor: Waryah CB; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia.; 2 Department of Medicine, Albert Einstein College of Medicine , Bronx, New York.; 3 Department of Cell Biology, Albert Einstein College of Medicine , Bronx, New York., Wells K; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia., Ulluwishewa D; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia., Chen-Tan N; 4 Curtin Electron Microscope Facility, John de Laeter Centre, Faculty of Science and Engineering, Curtin University , Perth, Western Australia., Gogoi-Tiwari J; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia., Ravensdale J; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia., Costantino P; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia., Gökçen A; 5 Department of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology , Gießen, Germany ., Vilcinskas A; 5 Department of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology , Gießen, Germany ., Wiesner J; 5 Department of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology , Gießen, Germany ., Mukkur T; 1 School of Biomedical Sciences, Faculty of Health Science, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia.

Publikováno v: Microbial drug resistance (Larchmont, N.Y.) [Microb Drug Resist] 2017 Apr; Vol. 23 (3), pp. 384-390. Date of Electronic Publication: 2016 Oct 18.