Zobrazeno 1 - 2
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pro vyhledávání: '"Ravendra Dhanraj"'
Background Ibrutinib, a Bruton Tyrosine Kinase inhibitor (iBTK), binds with target protein to arrest B-cell development and decrease microglia activation. Considering the emerging role of B and microglial cells in multiple sclerosis (MS) pathology, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c6f0543256ffd93089f48f07e01f3f3
https://doi.org/10.21203/rs.3.rs-2090036/v1
https://doi.org/10.21203/rs.3.rs-2090036/v1
Autor:
Deepa P. Ramasamy, Gisbert Weckbecker, Marilena Preda, Serena Liang, Ravendra Dhanraj, Michele Sveinsson, Michael G. Dwyer, Suyog Pol, Robert Zivadinov, Anna Schubart, Ferdinand Schweser
Publikováno v:
Experimental Neurology. 335:113488
Background The human myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (huMOG-EAE) model, generates B-cell driven demyelination in mice, making it a suitable multiple sclerosis model to study B cell depletion. Obje