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Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells

Autor: Knowles, Hj, Raval, Rr, Adrian Harris, Ratcliffe, Pj

Publikováno v: Scopus-Elsevier
Web of Science

Hypoxia-inducible factor (HIF) plays an important role in determining patterns of gene expression in cancer. HIF is down-regulated in oxygenated cells by a series of Fe (II) and 2-oxoglutarate dependent dioxygenases that hydroxylate specific residues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0059b42980ef86c7c2e85908eec2f944
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037446983&partnerID=MN8TOARS

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Akademický článek

"Intrasellar tumor-to-tumor metastasis: A single center experience with a systematic review".

Autor: Mansur G; Department of Neurological Surgery, Wexner Medical Center at The Ohio State University, Doan Hall N 1049, 460 W 10th Ave., Columbus, OH, 43210, USA., Alsavaf MB; Department of Neurological Surgery, Wexner Medical Center at The Ohio State University, Doan Hall N 1049, 460 W 10th Ave., Columbus, OH, 43210, USA.; Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center at The Ohio State University, Columbus, OH, USA., Pasquini L; Department of Neurological Surgery, Wexner Medical Center at The Ohio State University, Doan Hall N 1049, 460 W 10th Ave., Columbus, OH, 43210, USA., Abouammo MD; Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center at The Ohio State University, Columbus, OH, USA.; Department of Otorhinolaryngology-Head and Neck Surgery, Tanta University, Tanta, Egypt., Biswas C; Department of Neurological Surgery, Wexner Medical Center at The Ohio State University, Doan Hall N 1049, 460 W 10th Ave., Columbus, OH, 43210, USA., Kumar P; Department of Radiation Oncology, Wexner Medical Center at The Ohio State University, Columbus, OH, USA., Raval RR; Department of Radiation Oncology, Wexner Medical Center at The Ohio State University, Columbus, OH, USA., Kobalka P; Department of Pathology, Wexner Medical Center at The Ohio State University, Columbus, OH, USA., Carrau RL; Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center at The Ohio State University, Columbus, OH, USA., Prevedello DM; Department of Neurological Surgery, Wexner Medical Center at The Ohio State University, Doan Hall N 1049, 460 W 10th Ave., Columbus, OH, 43210, USA. daniel.prevedello@osumc.edu.

Publikováno v: Pituitary [Pituitary] 2024 Oct; Vol. 27 (5), pp. 455-467. Date of Electronic Publication: 2024 Aug 14.

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NRG-BN002: Phase I study of ipilimumab, nivolumab, and the combination in patients with newly diagnosed glioblastoma.

Autor: Sloan AE; Piedmont Healthcare, Atlanta, Georgia, USA.; Case Western Reserve University & Case Comprehensive Cancer Center, Cleveland, Ohio, USA., Winter K; NRG Oncology Statistics and Data Management Center/ACR, Philadelphia, Pennsylvania, USA.; American College of Radiology, Philadelphia, Pennsylvania, USA., Gilbert MR; Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA., Aldape K; Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA., Choi S; Case Western Reserve University & Case Comprehensive Cancer Center, Cleveland, Ohio, USA., Wen PY; Dana-Farber/Harvard Cancer Center, Boston, Massachusetts, USA., Butowski N; UCSF Medical Center-Mount Zion, San Francisco, California, USA., Iwamoto FM; Columbia University Minority Underserved NCORP, New York, New York, USA., Raval RR; Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA., Voloschin AD; Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, USA., Kamiya-Matsuoka C; MD Anderson Cancer Center, Houston, Texas, USA., Won M; NRG Oncology Statistics and Data Management Center/ACR, Philadelphia, Pennsylvania, USA.; Case Western Reserve University & Case Comprehensive Cancer Center, Cleveland, Ohio, USA., Mehta MP; Miami Cancer Institute, Miami, Florida, USA.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Sep 05; Vol. 26 (9), pp. 1628-1637.

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Disease Control and Toxicity Outcomes after Stereotactic Ablative Radiation Therapy for Recurrent and/or Metastatic Cancers in Young-Adult and Pediatric Patients.

Autor: Upadhyay R; Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Klamer B; Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Matsui J; Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Chakravarthy VB; Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Scharschmidt T; Department of Orthopedic Surgery, Nationwide Children's Hospital, Columbus, OH 43215, USA., Yeager N; Department of Pediatric Oncology, Nationwide Children's Hospital, Columbus, OH 43205, USA., Setty BA; Department of Pediatric Oncology, Nationwide Children's Hospital, Columbus, OH 43205, USA., Cripe TP; Department of Pediatric Oncology, Nationwide Children's Hospital, Columbus, OH 43205, USA., Roberts RD; Department of Pediatric Oncology, Nationwide Children's Hospital, Columbus, OH 43205, USA., Aldrink JH; Division of Pediatric Surgery, Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH 43205, USA., Singh R; Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Raval RR; Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Palmer JD; Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA., Baliga S; Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

Publikováno v: Cancers [Cancers (Basel)] 2024 May 30; Vol. 16 (11). Date of Electronic Publication: 2024 May 30.

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Safety and Feasibility of Stereotactic Radiosurgery for Patients with 15 or more Brain Metastases.

Autor: Upadhyay R; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Palmer JD; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Klamer BG; Center for Biostatistics, The Ohio State University, Columbus, Ohio., Perlow HK; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Schoenhals JE; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Ghose J; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Rajappa P; Department of Pediatrics and Neurological Surgery, The Ohio State University James Cancer Center, Columbus, OH and Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio., Blakaj DM; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Beyer S; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Grecula JC; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Sim AJ; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Lu L; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Zoller W; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Elder JB; Department of Neurological Surgery, The Ohio State University James Cancer Center, Columbus, Ohio., Chakravarti A; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Thomas E; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio., Raval RR; Department of Radiation Oncology, The Ohio State University James Cancer Center, Columbus, Ohio.

Publikováno v: Advances in radiation oncology [Adv Radiat Oncol] 2024 Apr 16; Vol. 9 (7), pp. 101509. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).

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