Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Raushan Kurmasheva"'
Autor:
Chia-Chin Wu, Licai Huang, Zhongting Zhang, Zhenlin Ju, Xingzhi Song, E. Anders Kolb, Wendong Zhang, Jonathan Gill, Min Ha, Malcolm A. Smith, Peter Houghton, Christopher L. Morton, Raushan Kurmasheva, John Maris, Yael Mosse, Yiling Lu, Richard Gorlick, P. Andrew Futreal, Hannah C. Beird
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Osteosarcoma is the most common primary bone malignancy in children and young adults, and it has few treatment options. As a result, there has been little improvement in survival outcomes in the past few decades. The need for models to test
Externí odkaz:
https://doaj.org/article/f8e627346ea440b7a5955c5d78e43866
Autor:
Cong Li, Gregory Moore, Umesh Muchhal, John Desjarlais, Matthew Bernett, Madeline Fort, Lingming Liang, Tao Osgood, Rodolfo Yabut, Sarav Kaliyaperumal, John Harrold, Jude Canon, Anna Rogojina, Raushan Kurmasheva, Peter Houghton, Olivier Nolan-Stevaux
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/9f44cfaebbde4a72a66c6cbe35d25b0b
Autor:
Paige Baldwin, Rostislav Likhotvorik, Nabeela Baig, Jodie Cropper, Ruth Carlson, Raushan Kurmasheva, Srinivas Sridhar
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The Pediatric Preclinical Testing Program previously identified the PARP inhibitor talazoparib (TLZ) as a means to potentiate temozolomide (TMZ) activity for the treatment of Ewing sarcoma. However, the combination of TLZ and TMZ has been toxic in bo
Externí odkaz:
https://doaj.org/article/a4a4ba5d5d4442e9ae412947b2b06715
Autor:
John M. Maris, Peter J. Houghton, Raushan Kurmasheva, Richard Gorlick, Brad St. Croix, Yang Feng, Steven Seaman, Yifei Wang, Samson Ghilu, Matthew Tsang, David Groff, Khushbu Patel, Kateryna Krytska, Jennifer Pogoriler, Daniel Martinez, Yael P. Mosse, Eric J. Earley, Stephen W. Erickson, Beverly A. Teicher, Malcolm A. Smith, E. Anders Kolb, Jarrett Lindsay, Nathan M. Kendsersky
Purpose:Patients with relapsed pediatric solid malignancies have few therapeutic options, and many of these patients die of their disease. B7-H3 is an immune checkpoint protein encoded by the CD276 gene that is overexpressed in many pediatric cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab5f7bd2b84ed5663da9919559459e8
https://doi.org/10.1158/1078-0432.c.6530132.v1
https://doi.org/10.1158/1078-0432.c.6530132.v1
Autor:
Douglas Harrison, Jonathan Gill, Michael Roth, Pooja Hingorani, Wendong Zhang, Beverly Teicher, Eric Earley, Stephen Erickson, Gregory Gatto, Raushan Kurmasheva, Peter Houghton, Malcolm Smith, E. Anders Kolb, Richard Gorlick
Publikováno v:
Pediatric Blood & Cancer. 70
Copanlisib is a pan-class I phosphoinositide 3-kinase (PI3K) inhibitor, with activity against all four PI3K class I isoforms (PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ). Whole-genome and RNA sequencing data have revealed several PI3K aberrations in osteosar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae86889bade1d629184b6463fcc67a7e
https://doi.org/10.1002/pbc.30017
https://doi.org/10.1002/pbc.30017
Autor:
Richard Gorlick, E. Anders Kolb, Yifei Wang, Peter Houghton, Raushan Kurmasheva, Yael Mosse, John Maris, Matthew Tsang, David Groff, Kateryna Krytska, Xiao-Nan Li, Yuchen Du, Jun Hasegawa, Nanae Izumi, Steven Neuhauser, Anuj Srivastava, Tim Stearns, Vivek Philip, Emily L. Jocoy, Jeff Chuang, Carol J. Bult, Beverly Teicher, Malcolm Smith
Publikováno v:
Cancer Research. 82:LB061-LB061
Introduction: B7-H3 (encoded by the CD276 gene) is suggested to act as an immune checkpoint molecule and is highly expressed in some pediatric solid tumors. Monoclonal antibodies targeting B7-H3 (8H9 and MGA271) are well-tolerated but have demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e43869bcd3975132ae1a20e7021c06
https://doi.org/10.1158/1538-7445.am2022-lb061
https://doi.org/10.1158/1538-7445.am2022-lb061
Autor:
Vanessa Del Pozo, Andrew J. Robles, Shaun Fontaine, Qianqian Liu, Joel E. Michalek, Peter J. Houghton, Raushan Kurmasheva
Publikováno v:
Cancer Research. 82:1086-1086
Introduction: The Ewing family of sarcomas is the fourth most common highly malignant childhood cancer. Current standard therapy is relatively ineffective for relapsed and metastatic Ewing sarcoma predominantly due to development of resistance to che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df8ba30c9b074ad31459c00a968699ff
https://doi.org/10.1158/1538-7445.am2022-1086
https://doi.org/10.1158/1538-7445.am2022-1086
Autor:
Raushan Kurmasheva, Olivier Nolan-Stevaux, John R. Desjarlais, Matthew J. Bernett, Peter J. Houghton, Rodolfo Yabut, Cong Li, Tao Osgood, Anna Rogojina, Umesh Muchhal, Madeline M. Fort, Jude Canon, Gregory T. Moore, John M. Harrold, Sarav Kaliyaperumal, Lingming Liang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Metastatic castration-resistant prostate cancer (mCRPC) and Ewing sarcoma (EWS) are diseases for which immune therapies could potentially provide benefit. STEAP1 (Six Transmembrane Epithelial Antigen of the Prostate 1) is a cell surface pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76db3a38e8fb53797b6ab1ab10f35a2
https://doaj.org/article/9f44cfaebbde4a72a66c6cbe35d25b0b
https://doaj.org/article/9f44cfaebbde4a72a66c6cbe35d25b0b
Autor:
Raushan Kurmasheva, Siyuan Zheng, Juechen Yang, Nighat Noureen, Peter J. Houghton, Yanbing Fang, Qilin Li, Xiao Jing Wang
Publikováno v:
Nucleic Acids Research
Although cancer is the leading cause of disease-related mortality in children, the relative rarity of pediatric cancers poses a significant challenge for developing novel therapeutics to further improve prognosis. Patient-derived xenograft (PDX) mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abea175c8e8c7b19bfd71d106285683
https://pubmed.ncbi.nlm.nih.gov/32810235
https://pubmed.ncbi.nlm.nih.gov/32810235
Autor:
Dauren Alimbetov, Rostislav Likhotvorik, Ruth Carlson, Raushan Kurmasheva, Jodie Cropper, Youngho Kwon
The Ewing family of sarcomas comprises the fourth most common highly aggressive bone tumor. Four of five Ewing sarcoma chemotherapeutics induce DNA damage, as does radiation therapy. At relapse, two additional DNA-damaging agents are routinely used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b65f18d00bdac53e666b1baed0a6bb5