Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Raul Y. Dagda"'
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 690
Parkinson’s Disease (PD) is a brain-degenerative disorder characterized by a progressive loss of midbrain dopamine neurons. Current standard-of-care includes oral administration of Levodopa to address motor symptoms, but this treatment is not disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9c62ac31e084808e69fb19e873f436
Publikováno v:
J Neurosci Res
Mutations in PTEN-induced kinase 1 (PINK1) lead to early onset autosomal recessive Parkinson's disease in humans. In healthy neurons, full-length PINK1 (fPINK1) is post-translationally cleaved into different lower molecular weight forms, and cleaved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0c83ca1f8180283d4ae1820ca2457e
https://doi.org/10.1002/jnr.24854
https://doi.org/10.1002/jnr.24854
PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA
Autor:
Charleen T. Chu, Raul Y. Dagda, Tania Das Banerjee, Emmanuel Vázquez-Mayorga, Monica Rice, Marisela Dagda, Ruben K. Dagda
Publikováno v:
Journal of Neurochemistry. 142:545-559
Mitochondrial Protein Kinase A (PKA) and PTEN-induced kinase 1 (PINK1), which is linked to Parkinson's disease, are two neuroprotective serine/threonine kinases that regulate dendrite remodeling, and mitochondrial function. We have previously shown t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759c6b6fe612a92fa5c2219ced2f620d
https://doi.org/10.1111/jnc.14083
https://doi.org/10.1111/jnc.14083
Autor:
Juliana L. Sacoman, Amanda R. Burnham-Marusich, Patricia M. Berninsone, Ruben K. Dagda, Raul Y. Dagda
Publikováno v:
Journal of Biological Chemistry. 292:4499-4518
O-Linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAcylation of target proteins and regulates numerous biological processes. OGT is encoded by a single gene that yields nucleocytosolic and mitochondrial isoforms. To date, the role of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8bca6ac5e1b98373750824116388a0
https://doi.org/10.1074/jbc.m116.726752
https://doi.org/10.1074/jbc.m116.726752
Publikováno v:
Mol Neurobiol
Psychological distress is a public health issue as it contributes to the development of human diseases including neuropathologies. Parkinson's disease (PD), a chronic, progressive neurodegenerative disorder, is caused by multiple factors including ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9043cf0fc77905a74751281eb1b59d
https://pubmed.ncbi.nlm.nih.gov/31836946
https://pubmed.ncbi.nlm.nih.gov/31836946
Publikováno v:
The Journal of Immunology. 202:126.39-126.39
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease characterized by profound fatigue, flu-like symptoms, trouble concentrating, and autonomic problems, all of which worsen after exertion. ME/CFS patients have impaired natural ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fb3bf662f85d0c2cc9faad7d570e37
https://doi.org/10.4049/jimmunol.202.supp.126.39
https://doi.org/10.4049/jimmunol.202.supp.126.39
Autor:
Jason Callio, Ruben K. Dagda, Charleen T. Chu, Tania Das Banerjee, Irene Pien, Raul Y. Dagda, Ruth Wang, Kent Z.Q. Wang, Jianhui Zhu
Publikováno v:
Journal of Neurochemistry. 128:864-877
The subcellular compartmentalization of kinase activity allows for regulation of distinct cellular processes involved in cell differentiation or survival. The PTEN-induced kinase 1 (PINK1), which is linked to Parkinson's disease, is a neuroprotective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b544d1e5373584c5352da5d93a5135
https://doi.org/10.1111/jnc.12494
https://doi.org/10.1111/jnc.12494
Autor:
Ruin Moaddel, Marisela Dagda, Aveline Hewetson, Susan E. Bergeson, George I. Henderson, Mitesh Sanghvi, Inna I. Kruman, Anna Kate Fowler, Yukun Chen, Rajiv G. Agrawal, Silvia Balbo, Raul Y. Dagda, Ryan J. Hogue
Publikováno v:
Journal of Biological Chemistry. 287:43533-43542
The brain is one of the major targets of chronic alcohol abuse. Yet the fundamental mechanisms underlying alcohol-mediated brain damage remain unclear. The products of alcohol metabolism cause DNA damage, which in conditions of DNA repair dysfunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d42746abfad40f9c8100ee7959c397
https://doi.org/10.1074/jbc.m112.401497
https://doi.org/10.1074/jbc.m112.401497
Autor:
Alejandro Martínez-Martínez, Raul Y. Dagda, Cynthia K. Coronado-Ramírez, Carlos A. Domínguez-Solís, Ruben K. Dagda, Emmanuel Vázquez-Mayorga, Ángel G. Díaz-Sánchez
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 8, p 1346 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 8; Pages: 1346
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 8; Pages: 1346
International Journal of Molecular Sciences
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson’s disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af03698a60cd204cc6e966014f925f31
http://www.mdpi.com/1422-0067/17/8/1346
http://www.mdpi.com/1422-0067/17/8/1346
Autor:
Ming-Chien Chyu, Jia-Sheng Wang, Raul Y. Dagda, Chwan-Li Shen, Chuanwen Lu, James K. Yeh, Jay J. Cao, Samuel Chanjaplammootil, Weimin Gao
Publikováno v:
Nutrition Research. 32:448-457
This study investigates the effects of green tea polyphenols (GTPs) on body composition and bone properties along with mechanisms in obese female rats. Thirty-six 3-month-old Sprague Dawley female rats were fed either a low-fat (LF) or a high-fat (HF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3814f12bf7a7dec9470ffa02882cfd95
https://doi.org/10.1016/j.nutres.2012.05.001
https://doi.org/10.1016/j.nutres.2012.05.001