The Epigenetic Regulation in Plant Specialized Metabolism: DNA Methylation Limits Paclitaxel in vitro Biotechnological Production

Autor: Ainoa Escrich, Rosa M. Cusido, Mercedes Bonfill, Javier Palazon, Raul Sanchez-Muñoz, Elisabeth Moyano

Publikováno v: Frontiers in Plant Science, Vol 13 (2022)

Environmental conditions are key factors in the modulation of the epigenetic mechanisms regulating gene expression in plants. Specifically, the maintenance of cell cultures in optimal in vitro conditions alters methylation patterns and, consequently,

Externí odkaz: https://doaj.org/article/a563a004cd504128aa2bb65e86e109ec

Effect of Polyploidy Induction on Natural Metabolite Production in Medicinal Plants

Autor: Hadi Madani, Ainoa Escrich, Bahman Hosseini, Raul Sanchez-Muñoz, Abbas Khojasteh, Javier Palazon

Publikováno v: Biomolecules, Vol 11, Iss 6, p 899 (2021)

Polyploidy plays an important role in plant diversification and speciation. The ploidy level of plants is associated with morphological and biochemical characteristics, and its modification has been used as a strategy to alter the quantitative and qu

Externí odkaz: https://doaj.org/article/b857897307f749788007ec9359065942

Efficient cut and paste: Directional oligodeoxynucleotide-based targeted insertion (DOTI) as a precise genome editing method

Autor: Raul Sanchez-Muñoz

Publikováno v: The Plant Cell.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::755c8ee300274475cf899d2541a9d1dc
https://doi.org/10.1093/plcell/koad145

Stimulation of defense reactions in potato against Pectobacterium sp

Autor: Rachida Yahaoui Zaidi, Javier Palazon, Rosa M. Cusidó, Said Hachoud, Raul Sanchez-Muñoz, Farid Zaidi

Publikováno v: Journal of General Plant Pathology. 85:257-272

The pesticides used to tackle potato pathogens, including bacteria, are environmentally damaging, so more sustainable treatments are needed. Because plant defense-related hormones such as methyl jasmonate and salicylic acid and the elicitor chitosan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16c73534a048b54debd5525237bd4594
https://doi.org/10.1007/s10327-019-00843-z

A Novel Hydroxylation Step in the Taxane Biosynthetic Pathway: A New Approach to Paclitaxel Production by Synthetic Biology

Autor: Rosa M. Cusidó, Mercedes Bonfill, Raul Sanchez-Muñoz, Elisabeth Moyano, Javier Palazon, Lorena Almagro, Edgar Perez-Mata

Publikováno v: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology

Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa666fcafa12ca7437708d8e640dd93
https://pubmed.ncbi.nlm.nih.gov/32528936