Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Raul Ruiz Esponda"'
Autor:
Adam R. Konopka, Raul Ruiz Esponda, Matthew M. Robinson, Matthew L. Johnson, Rickey E. Carter, Michele Schiavon, Claudio Cobelli, Fredric E. Wondisford, Ian R. Lanza, K. Sreekumaran Nair
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1394-1400 (2016)
Summary: The therapeutic mechanism of metformin action remains incompletely understood. Whether metformin inhibits glucagon-stimulated endogenous glucose production (EGP), as in preclinical studies, is unclear in humans. To test this hypothesis, we s
Externí odkaz:
https://doaj.org/article/3a0445036a964a44b608147e0fc0b1cc
Autor:
David B. Savage, Antonio Vidal-Puig, Heather P. Harding, Sergio Rodriguez-Cuenca, Fiona M. Gribble, Naveed Sattar, John Tadross, Pranali Taskar, Emily L. Miedzybrodzka, Sam Virtue, Ming Yang, Y. C. Loraine Tung, Irene Cimino, Anthony P. Coll, Stephen O'Rahilly, Audrey Melvin, K. Sreekumaran Nair, Bernard B. Allan, Giles S.H. Yeo, Deborah A. Goldspink, David Ron, Jeffrey T.-J. Huang, Rute A. Tomaz, David Preiss, Satish Patel, Paul Welsh, Adam R. Konopka, Michael Chen, Frank Reimann, Ludovic Vallier, Raul Ruiz Esponda, Nicholas J. Wareham, Debra Rimmington
Publikováno v:
Nature
Metformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk1,2. More than 60% of this effect is attributable to the ability of metformin to lower body weight in a sustained manne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7e813ae9add3737a91d92d4f91fd84
https://eprints.gla.ac.uk/207415/7/207415.pdf
https://eprints.gla.ac.uk/207415/7/207415.pdf
Autor:
Matthew L. Johnson, Adam R. Konopka, Ian R. Lanza, Rickey E. Carter, Surendra Dasari, K. Sreekumaran Nair, Matthew M. Robinson, Raul Ruiz Esponda, Shankarappa Manjunatha
Publikováno v:
Cell Metabolism. 25:581-592
The molecular transducers of benefits from different exercise modalities remain incompletely defined. Here we report that 12 weeks of high-intensity aerobic interval (HIIT), resistance (RT), and combined exercise training enhanced insulin sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f28bb342c931fa5febb3a0b421d622
https://doi.org/10.1016/j.cmet.2017.02.009
https://doi.org/10.1016/j.cmet.2017.02.009
Publikováno v:
Journal of the Endocrine Society
Objective: Familial partial lipodystrophy (FPLD) syndromes are rare and characterized by variable loss of adipose tissue in some areas of the body with excess deposition of fat in other areas, and complex metabolic derangements. We present a patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e898157c2b742dd2e8a14d9edc914141
http://europepmc.org/articles/PMC6552779
http://europepmc.org/articles/PMC6552779
Autor:
Sergio Rodriguez-Cuenca, K. Sreekumaran Nair, Fiona M. Gribble, Deborah A. Goldspink, Nicholas J. Wareham, Emily L. Miedzybrodzka, Debra Rimmington, Y. C. Loraine Tung, Giles S.H. Yeo, Audrey Melvin, Bernard B. Allan, Ming Yang, John Tadross, Heather P. Harding, Ludovic Vallier, David B. Savage, David Preiss, Raul Ruiz Esponda, Anthony P. Coll, Antonio Vidal-Puig, Adam R. Konopka, Pranali Taskar, Irene Cimino, Samuel Virtue, Michael Chen, Frank Reimann, Jeffrey T.-J. Huang, Rute A. Tomaz, Satish Patel, Paul Welsh, Stephen O'Rahilly, Naveed Sattar, David Ron
Publikováno v:
Nature. 578:E24-E24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c53be780f4a38d09d66c1042c28261
https://doi.org/10.1038/s41586-020-2031-4
https://doi.org/10.1038/s41586-020-2031-4
Autor:
Ivonne Coraza, Eric Y. Yang, Catherine N. Vu, Evelyn Chang, Baiba K. Gillard, Ron C. Hoogeveen, Ashok Balasubramanyam, Henry J. Pownall, Raul Ruiz-Esponda
Publikováno v:
Metabolism. 62:1014-1020
Plasma triglycerides (TG) and HDL-C are inversely related in Metabolic Syndrome (MetS), due to exchange of VLDL-TG for HDL-cholesteryl esters catalyzed by cholesteryl ester transfer protein (CETP). We investigated the relationship of TG to HDL-C in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8ebc953fbda4149508549af2df8f78
https://doi.org/10.1016/j.metabol.2013.01.020
https://doi.org/10.1016/j.metabol.2013.01.020
Autor:
Baiba K. Gillard, Joe L. Raya, Ashok Balasubramanyam, Dinakar Iyer, Raul Ruiz-Esponda, Henry J. Pownall, Ivonne Coraza
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1714-1721
Objective— HIV patients on antiretroviral therapy (HIV/ART) exhibit a unique atherogenic dyslipidemic profile with hypertriglyceridemia (HTG) and low plasma concentrations of high-density lipoprotein (HDL) cholesterol. In the Heart Positive Study o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f7f75231e777ef014f3328fdaeeacf1
https://doi.org/10.1161/atvbaha.113.301538
https://doi.org/10.1161/atvbaha.113.301538
Autor:
Klaus Distelmaier, Antigoni Z. Lalia, John D. Port, Matthew L. Johnson, Surendra Dasari, K. Sreekumaran Nair, Matthew M. Robinson, Raul Ruiz Esponda, Ian R. Lanza, Adam R. Konopka, Maria T. Glavin
Context:Numerous factors are purported to influence insulin sensitivity including age, adiposity, mitochondrial function, and physical fitness. Univariate associations cannot address the complexity of insulin resistance or the interrelationship among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0986279c41a0d75f0c28e98d66c5d4
https://europepmc.org/articles/PMC4880121/
https://europepmc.org/articles/PMC4880121/
Autor:
Matthew M. Robinson, Claudio Cobelli, Raul Ruiz Esponda, Ian R. Lanza, Michele Schiavon, Adam R. Konopka, Matthew L. Johnson, Fredric E. Wondisford, Rickey E. Carter, K. Sreekumaran Nair
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1394-1400 (2016)
Summary: The therapeutic mechanism of metformin action remains incompletely understood. Whether metformin inhibits glucagon-stimulated endogenous glucose production (EGP), as in preclinical studies, is unclear in humans. To test this hypothesis, we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597a00214a9e36a647bc8d7f1a4a3e28
https://doi.org/10.1016/j.celrep.2018.05.027
https://doi.org/10.1016/j.celrep.2018.05.027