Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Raul O Cosentino"'
Autor:
Raul O Cosentino, Fernán Agüero
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 7, p e1777 (2012)
Trypanosoma cruzi is the causative agent of Chagas' Disease. The parasite has a complex population structure, with six major evolutionary lineages, some of which have apparently resulted from ancestral hybridization events. Because there are importan
Externí odkaz:
https://doaj.org/article/de07c1fa95f1442a91bd45a5850d0304
Publikováno v:
NAR Genomics and Bioinformatics
To date, most reference genomes represent a mosaic consensus sequence in which the homologous chromosomes are collapsed into one sequence. This approach produces sequence artefacts and impedes analyses of allele-specific mechanisms. Here, we report a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fd35af367a521551e90dd9814c9b72
https://doi.org/10.1093/nargab/lqab082
https://doi.org/10.1093/nargab/lqab082
Publikováno v:
BioRxiv
bioRxiv
bioRxiv
Many eukaryotic organisms are diploid or even polyploid, i.e. they harbour two or more independent copies of each chromosome. Yet, to date most reference genome assemblies represent a mosaic consensus sequence in which the homologous chromosomes have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5044167c9863a39599dc3a1907029687
https://doi.org/10.1101/2021.04.13.439624
https://doi.org/10.1101/2021.04.13.439624
Autor:
Raul O Cosentino, Amelie J. Kraus
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992096
Ribosomes are the machinery responsible for reading mRNAs and translating them into proteins. The ribosome profiling approach is based on high-throughput sequencing of ribosome-protected mRNAs. RNAs not harboring ribosomes are removed by nuclease dig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6406fd3837770a70816c312da704da71
https://doi.org/10.1007/978-1-4939-9210-2_5
https://doi.org/10.1007/978-1-4939-9210-2_5
Publikováno v:
Nucleic Acids Research
Despite their importance for most DNA-templated processes, the function of individual histone modifications has remained largely unknown because in vivo mutational analyses are lacking. The reason for this is that histone genes are encoded by multige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cf3da34b5d8a2b7c982db7597b6779
Autor:
Noam Kaplan, Raul O Cosentino, Jörg Vogel, Christian J. Janzen, Thomas D. Otto, Carolin Wedel, Antoine-Emmanuel Saliba, T. Nicolai Siegel, Sascha Steinbiss, Julien Guizetti, Konrad U. Förstner, Robert Sebra, Laura S. M. Müller, Panagiota Arampatzi
Publikováno v:
Nature
Nature, Epub ahead of
Nature, Epub ahead of
Many evolutionarily distant pathogenic organisms have evolved similar survival strategies to evade the immune responses of their hosts. These include antigenic variation, through which an infecting organism prevents clearance by periodically altering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155971f66995ef1052c9c5fd521b60a9
https://hdl.handle.net/10033/621576
https://hdl.handle.net/10033/621576
Autor:
Raul O Cosentino, Fernán Agüero
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96762 (2014)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
In Trypanosoma cruzi the isoprenoid and sterol biosynthesis pathways are validated targets for chemotherapeutic intervention. In this work we present a study of the genetic diversity observed in genes from these pathways. Using a number of bioinforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1924ca0046fdb6e90ea306de41eb352
http://europepmc.org/articles/PMC4020770?pdf=render
http://europepmc.org/articles/PMC4020770?pdf=render
Background. Sterols such as cholesterol, are important components of cellular membranes. But unlike mammalian cells, the main sterols found in the membranes of trypanosomes and fungi are ergosterol, and other 24-methyl sterols, which are required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96950ef33a41e78fb73b215fe62e762c
https://doi.org/10.7287/peerj.preprints.44v1
https://doi.org/10.7287/peerj.preprints.44v1
Autor:
Fernán Agüero, Leonardo Gabriel Panunzi, Daniel O. Sánchez, Raul O Cosentino, Alejandro A. Ackermann
Publikováno v:
BMC Genomics
BMC Genomics, Vol 13, Iss 1, p 736 (2012)
BMC Genomics, Vol 13, Iss 1, p 736 (2012)
Background Trypanosoma cruzi, the causal agent of Chagas Disease, affects more than 16 million people in Latin America. The clinical outcome of the disease results from a complex interplay between environmental factors and the genetic background of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f55c24b823b341b3f7b863b760a083