Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Raul Martínez-Zaguilán"'
Autor:
Dalia Martinez-Marin, Rebecca A Helmer, Gurvinder Kaur, Rachel L Washburn, Raul Martinez-Zaguilan, Souad R Sennone, Jannette M Dufour, Beverly S Chilton
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291023 (2023)
Helicase-like transcription factor (HLTF) also known as SMARCA3, protects genome integrity. A tumor suppressor, HLTF is expressed in tumor cells but not in the tumor microenvironment (TME) in early-stage colorectal cancer (CRC). With disease progress
Externí odkaz:
https://doaj.org/article/512da3d99a5b422e82ecd16ec3246e4a
Autor:
Gurvinder Kaur, Rebecca A Helmer, Dalia Martinez-Marin, Souad R Sennoune, Rachel L Washburn, Raul Martinez-Zaguilan, Jannette M Dufour, Beverly S Chilton
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0286109 (2023)
Epigenetic mechanisms are integral to pancreatic β cell function. Promoter hypermethylation of the helicase like-transcription factor (HLTF) gene-a component of the cellular DNA damage response that contributes to genome stability-has been implicate
Externí odkaz:
https://doaj.org/article/c2e548e68462440ca1db025060961407
Autor:
Rebecca A Helmer, Raul Martinez-Zaguilan, Gurvinder Kaur, Lisa A Smith, Jannette M Dufour, Beverly S Chilton
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251132 (2021)
Methylation of the HLTF gene in colorectal cancer (CRC) cells occurs more frequently in men than women. Progressive epigenetic silencing of HLTF in tumor cells is accompanied by negligible expression in the tumor microenvironment (TME). Cell line-der
Externí odkaz:
https://doaj.org/article/8ecbe03233c9424b873ff31a5f9221a6
Autor:
Rebecca A Helmer, Raul Martínez-Zaguilán, Janet S Dertien, Candra Fulford, Oded Foreman, Vasum Peiris, Beverly S Chilton
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80461 (2013)
HLTF/Hltf regulates transcription, remodels chromatin, and coordinates DNA damage repair. Hltf is expressed in mouse brain and heart during embryonic and postnatal development. Silencing Hltf is semilethal. Seventy-four percent of congenic C57BL/6J H
Externí odkaz:
https://doaj.org/article/0c1e717c2a1a428192cd73e6e20cc255
Autor:
Jose D, Rojas, Souad R, Sennoune, Gloria M, Martinez, Karina, Bakunts, Cynthia J, Meininger, Guoyao, Wu, Donald E, Wesson, Elisabeth A, Seftor, Mary J C, Hendrix, Raul, Martínez-Zaguilán
Publikováno v:
Journal of cellular physiology. 201(2)
Angiogenesis requires invasion of extracellular matrix (ECM) proteins by endothelial cells and occurs in hypoxic and acidic environments that are not conducive for cell growth and survival. We hypothesize that angiogenic cells must exhibit a unique s
Publikováno v:
Cell biochemistry and biophysics. 40(2)
Vacuolar-type H+-adenosine triphosphatase (V-ATPase) is one of the most fundamental enzymes in nature. V-ATPases are responsible for the regulation of proton concentration in the intracellular acidic compartments. It has similar structure with the mi
Publikováno v:
Cell Biochemistry & Biophysics; Apr2004, Vol. 40 Issue 2, p185-206, 22p
Autor:
Gurvinder Kaur, Rebecca A Helmer, Lisa A Smith, Raul Martinez-Zaguilan, Jannette M Dufour, Beverly S Chilton
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200211 (2018)
Hltf is regulated by intron retention, and global Hltf-deletion causes perinatal lethality from hypoglycemia. In heart, full-length Hltf is a transcriptional regulator of Hif-1α that controls transport systems. Thus, we tested the hypothesis that Hl
Externí odkaz:
https://doaj.org/article/485b39849fc04804b69131ee5a7e66c7
Conference
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Conference
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