Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Raul M Torres"'
Autor:
Sophie Hillion, Anjelica Miranda, Christelle Le Dantec, Marina Boudigou, Laëtitia Le Pottier, Divi Cornec, Raul M. Torres, Roberta Pelanda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Precise regulation of B cell differentiation is essential for an effective adaptive immune response. Here, we show that B cell development in mice with B cell-specific Maf deletion is unaffected, but marginal zone B cells, germinal centre B
Externí odkaz:
https://doaj.org/article/60cfe228c0f8482f9434fff8a01bcaba
Autor:
Christopher S Malarkey, Claire E Gustafson, Jessica F Saifee, Raul M Torres, Mair E A Churchill, Edward N Janoff
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157157 (2016)
Mitochondrial transcription factor A (TFAM) had previously been shown to act as a damage associated molecular pattern with the ability to enhance CpG-A phosphorothioate oligodeoxynucleotide (ODN)-mediated stimulation of IFNα production from human pl
Externí odkaz:
https://doaj.org/article/a988412491364942ba84cc96a8b56d56
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114283- (2024)
Summary: Resolving the molecular mechanisms of central B cell tolerance might unveil strategies that prevent autoimmunity. Here, using a mouse model of central B cell tolerance in which Forkhead box protein O1 (Foxo1) is either deleted or over-expres
Externí odkaz:
https://doaj.org/article/1651e06ccab54ede8686c00898c8691d
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Exposure to second hand tobacco smoke is associated with the development and/or exacerbation of several different pulmonary diseases in humans. To better understand the possible effects of second hand smoke exposure in humans, we sub-chronically (4 w
Externí odkaz:
https://doaj.org/article/2bcdddf4ee5548b5918421eba91bd107
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31632 (2012)
The Glucocorticoid-Induced Tumor necrosis factor Receptor GITR, a member of the tumor necrosis factor receptor superfamily, has been shown to be important in modulating immune responses in the context of T cell immunity. B lymphocytes also express GI
Externí odkaz:
https://doaj.org/article/4b1d5d5c638d4db8a8309e0c39fcc9ca
Autor:
Jacqueline A. Turner, Malia A. Fredrickson, Marc D’Antonio, Elizabeth Katsnelson, Morgan MacBeth, Robert Van Gulick, Tugs-Saikhan Chimed, Martin McCarter, Angelo D’Alessandro, William A. Robinson, Kasey L. Couts, Roberta Pelanda, Jared Klarquist, Richard P. Tobin, Raul M. Torres
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Lysophosphatidic acid (LPA) is a bioactive lipid which increases in concentration locally and systemically across different cancer types. Yet, the exact mechanism(s) of how LPA affects CD8 T cell immunosurveillance during tumor progression r
Externí odkaz:
https://doaj.org/article/9dfc6ffa89df499aaa7f4fbb3ebcf2ec
Autor:
Jacqueline A. Turner, Ali Hakimi, Hannah Lee, Jeffrey T. Schowinsky, Jeffrey M. Sippel, Bradford J. Siegele, Raul M. Torres, William A. Robinson
Publikováno v:
Case Reports in Immunology, Vol 2024 (2024)
The Castleman triad has been described in a select few patients presenting with a retroperitoneal mass, mucocutaneous pemphigus vulgaris, and bronchiolitis obliterans. Here, we describe the Castleman triad in a 19-year-old male with unicentric hyalin
Externí odkaz:
https://doaj.org/article/1e69e9c95320442ea9383cccec73152c
Autor:
Moriah J. Castleman, Adriana Luna Santos, Kelsey E. Lesteberg, James P. Maloney, William J. Janssen, Kara J. Mould, J. David Beckham, Roberta Pelanda, Raul M. Torres
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Memory B cells are comprised of unswitched (CD27+IgD+) and switched (CD27+IgD-) subsets. The origin and function of unswitched human memory B cells are debated in the literature, whereas switched memory B cells are primed to respond to recurrent infe
Externí odkaz:
https://doaj.org/article/3fcc280c7b4545769308a4722574f5b1
Autor:
Yuki Fujiwara, Robert J. Torphy, Yi Sun, Emily N. Miller, Felix Ho, Nicholas Borcherding, Tuoqi Wu, Raul M. Torres, Weizhou Zhang, Richard D. Schulick, Yuwen Zhu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Proliferative and effector functions of T cells are determined by T cell receptor signalling and modulated by activator and inhibitory co-receptors. Authors report here that the G-protein-coupled receptor GPR171 functions as a co-inhibitor of T cell
Externí odkaz:
https://doaj.org/article/4515b28636ca4c3b83d2b6c3169e1d1a
Autor:
Moriah J. Castleman, Megan M. Stumpf, Nicholas R. Therrien, Mia J. Smith, Kelsey E. Lesteberg, Brent E. Palmer, James P. Maloney, William J. Janssen, Kara J. Mould, J. David Beckham, Roberta Pelanda, Raul M. Torres
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Double negative (DN) B cells (CD27-IgD-) comprise a heterogenous population of DN1, DN2, and the recently described DN3 and DN4 subsets. In autoimmune disease, DN2 cells are reported to be precursors to autoreactive antibody secreting cells and expan
Externí odkaz:
https://doaj.org/article/8100c6e2e03b46248febc8c0f54fdcb3