Endothelial dysfunction and persistent inflammation in severe post-COVID-19 patients: implications for gas exchange

Autor: Enrique Alfaro, Elena Díaz-García, Sara García-Tovar, Raúl Galera, Raquel Casitas, María Torres-Vargas, Cristina López-Fernández, José M. Añón, Francisco García-Río, Carolina Cubillos-Zapata

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)

Abstract Background Understanding the enduring respiratory consequences of severe COVID-19 is crucial for comprehensive patient care. This study aims to evaluate the impact of post-COVID conditions on respiratory sequelae of severe acute respiratory

Externí odkaz: https://doaj.org/article/0736934691d14c11a0a766f34ea505bc

Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score

Autor: Juan Salillas, Miguel Fernández Huerta, Patricio González-Pizarro, Francisco Javier Membrillo, Raul Galera, Jesús Rodríguez-Baño, Lydia Galvez, Juan Cuadros-González, Aina Gabarrell-Pascuet, Jorge Diaz-Garzon, INMA JARRIN, Claudia González-Rico, Alicia Rico Nieto, Cristina Cervera, Carlos Bea Serrano, Alberto Ouro Villasante, Guillermo Ruiz-Carrascoso, Beatriz Díaz-Pollán, María del mar Arcos Rueda, Julio Garcia-Rodriguez, BELEN GUTIÉRREZ-GUTIÉRREZ, MARCO ANTONIO SEMPERE ALCOCER, Cristina Verdú Sánchez, Lucía Hernández-Rivas, Guillermo Cuervo, Alejandro Smithson, Miguel Torralba, Iván Bloise, Alexander Rombauts, Carlos Toro, Lucio Jesus García-Fraile Fraile, Alejandro García-Ruiz de Morales, Cecilia Tortajada, KAPIL LAXMAN NANWANI NANWANI, Lorena De la Mora Cañizo, Laia Lorenzo-Esteller, Jorge Álvarez Troncoso, Cristina Roca Oporto, Alejandro Martin-Quiros, José A. Oteo, Eduardo Malmierca Corral, Stefan Stewart, Jerónimo Pachón, Almudena Gutiérrez-Arroyo, Moreno-Cuerda Victor, Carlos Carpio, Emilio Cendejas-Bueno, Pilar Fernandez-Calle, Antonio Javier Carcas Sansuán, Alexy Inciarte, Pablo Ryan, Luis Puente-Maestu, Jesús Troya García, Francisco de Asís Alcántara Nicolás, Gabriela Abelenda-Alonso, Natividad Benito, Daniel Prieto Arribas, Jesus Mingorance, Jose L Del Pozo, Jordi Carratala, Cristina Marcelo, Marta Ruiz-Algueró, Sarah CARO BRAGADO, Juan Berenguer, Vicens Diaz-Brito, Víctor Hontañón Antoñana, Julen Cadiñanos, Jose Arribas, María Jesús Jaras Hernández, Henar Calvo Sánchez, Elisa Cordero

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Thorax
Thorax 2021;76:920-929
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Biblos-e Archivo. Repositorio Institucional de la UAM

COVID-19@Spain and COVID@HULP Study.
[Objective] To develop and validate a prediction model of mortality in patients with COVID-19 attending hospital emergency rooms.
[Design] Multivariable prognostic prediction model.
[Setting] 127 Sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b1e8aca9095ee98bad2ef70a3fceb5
http://hdl.handle.net/20.500.12105/14214

Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity

Autor: Enrique Alfaro, Elena Díaz-García, Sara García-Tovar, Ester Zamarrón, Alberto Mangas, Raúl Galera, Kapil Nanwani-Nanwani, Rebeca Pérez-de-Diego, Eduardo López-Collazo, Francisco García-Río, Carolina Cubillos-Zapata

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

COVID-19 has emerged as a devastating disease in the last 2 years. Many authors appointed to the importance of kallikrein-kinin system (KKS) in COVID-19 pathophysiology as it is involved in inflammation, vascular homeostasis, and coagulation. We aim

Externí odkaz: https://doaj.org/article/03e935ec7f02480b8737ada3d7a80cd8

Upregulated Proteasome Subunits in COVID-19 Patients: A Link with Hypoxemia, Lymphopenia and Inflammation

Autor: Enrique Alfaro, Elena Díaz-García, Sara García-Tovar, Ester Zamarrón, Alberto Mangas, Raúl Galera, Eduardo López-Collazo, Francisco García-Rio, Carolina Cubillos-Zapata

Publikováno v: Biomolecules, Vol 12, Iss 3, p 442 (2022)

Severe COVID-19 disease leads to hypoxemia, inflammation and lymphopenia. Viral infection induces cellular stress and causes the activation of the innate immune response. The ubiquitin-proteasome system (UPS) is highly implicated in viral immune resp

Externí odkaz: https://doaj.org/article/d0147468885242f6b839c4075dba9285

Prognostic Value of the Six-Second Spirometry in Patients with Chronic Obstructive Pulmonary Disease: A Cohort Study.

Autor: Eva Prats, Elena Tejero, Paloma Pardo, Adelaida Gavilán, Raúl Galera, José Ramón Donado, Miguel Ángel Racionero, Raquel Casitas, Antonio Zapatero, Francisco García-Río

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0140855 (2015)

The six-second spirometry has been proposed as an alternative to diagnose airflow limitation, although its prognostic value in patients with chronic obstructive pulmonary disease (COPD) remains unknown. The purpose of this study was to determine the

Externí odkaz: https://doaj.org/article/1f00aec238bd4b1ba64852a4413f33be