Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Raul E. Salinas"'
Autor:
Hashim M. Al-Hashimi, Maria A. Schumacher, Allison L. Stelling, Amy Y. Liu, Wenjie Zeng, Raul E. Salinas
Publikováno v:
Angewandte Chemie International Edition. 58:12010-12013
Hoogsteen DNA base pairs (bps) are an alternative base pairing to canonical Watson-Crick bps and are thought to play important biochemical roles. Hoogsteen bps have been reported in a handful of X-ray structures of protein-DNA complexes. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866360c72c6761208a3b7ed1aa9e400f
https://doi.org/10.1002/anie.201902693
https://doi.org/10.1002/anie.201902693
Autor:
Patrick C. Seed, Ahreen Allana, Cristina A Salinas, Mehreen Arshad, Asia Khan, Shahida Qureshi, Lauren Hale, Najeeb Rahman, Raul E. Salinas, Aneeta Hotwani, Alondra Diaz, Anita Kaniz Mehdi Zaidi, Ali Faisal Saleem
Publikováno v:
Antibiotics
Volume 9
Issue 6
Antibiotics, Vol 9, Iss 286, p 286 (2020)
Volume 9
Issue 6
Antibiotics, Vol 9, Iss 286, p 286 (2020)
The recent rapid rise of multi-drug resistant Enterobacteriaceae (MDR-E) is threatening the treatment of common infectious diseases. Infections with such strains lead to increased mortality and morbidity. Using a cross-sectional study, we aimed to es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6770a6c4635506aa2a2ca64d299a459c
Autor:
Raul E. Salinas, Gregory M.K. Poon, Mimi Fang, Zachery Mielko, Suela Xhani, Alon Senitzki, Hashim M. Al-Hashimi, Maria A. Schumacher, Miles A. Pufall, Atul Rangadurai, Tali E. Haran, Honglue Shi, Raluca Gordân, Harshit Sahay, Ariel Afek
Publikováno v:
Nature
Transcription factors recognize specific genomic sequences to regulate complex gene-expression programs. Although it is well-established that transcription factors bind to specific DNA sequences using a combination of base readout and shape recogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1e7de883a8dab8a462a4549cee163b
https://pubmed.ncbi.nlm.nih.gov/33087865
https://pubmed.ncbi.nlm.nih.gov/33087865
Autor:
Stacy M. Horner, Jeffrey R. Barker, Soo Chan Lee, Robert J. Carroll, Mark R. DeLong, Joseph Heitman, Liuyang Wang, Kelly J. Pittman, Joshua C. Denny, Kyle D. Gibbs, Graham D. Williams, Tom Balmat, Anusha M. Gopalakrishnan, Andy Ingham, Alejandro L. Antonia, Dennis C. Ko, Raphael H. Valdivia, Ian B. Stanaway, David R. Crosslin, Gail P. Jarvik, Raul E. Salinas
Pathogens have been a strong driving force for natural selection. Therefore, understanding how human genetic differences impact infection-related cellular traits can mechanistically link genetic variation to disease susceptibility. Here we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a49984067e0e672b643409f84b457bc
https://europepmc.org/articles/PMC6093297/
https://europepmc.org/articles/PMC6093297/
Autor:
Thomas N. Williams, Raul E. Salinas, Patricia Njuguna, J. W. Thompson, Neema Mturi, Christopher W. Woods, Emily R Ko, James J. Gilchrist, M.A. Moseley, Kelly J. Pittman, Dennis C. Ko, Matti Pirinen, Geoffrey S. Ginsburg, Douglas C. Rouse, Hill Avs., Liuyang Wang, Ephraim L. Tsalik, Laura G. Dubois, Raymond J. Langley, Sarah L. Jaslow, Salim Mwarumba, Anna Rautanen, Scott Jag.
Publikováno v:
Science Advances
The substrate of the methionine salvage pathway, methylthioadenosine, is a predictor of death in sepsis patients.
Sepsis is a deleterious inflammatory response to infection with high mortality. Reliable sepsis biomarkers could improve diagnosis,
Sepsis is a deleterious inflammatory response to infection with high mortality. Reliable sepsis biomarkers could improve diagnosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3a44673bec4edae1f3ffeaddabe4d0
https://researchonline.lshtm.ac.uk/id/eprint/3716685/1/1602096.PMC5342653.pdf
https://researchonline.lshtm.ac.uk/id/eprint/3716685/1/1602096.PMC5342653.pdf
Autor:
Monica I. Thomas, Raul E. Salinas, Dennis C. Ko, Kajal P. Shukla, Cassandra Ogohara, Samuel I. Miller
Publikováno v:
Molecular Biology of the Cell. 25:76-86
Pyroptosis is proinflammatory cell death that occurs in response to certain microbes. Activation of the protease caspase-1 by molecular platforms called inflammasomes is required for pyroptosis. We performed a cellular genome-wide association study (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58345c3383aaea1fa4f6805f5671bc10
https://doi.org/10.1091/mbc.e13-06-0294
https://doi.org/10.1091/mbc.e13-06-0294
Autor:
Mariano A. Garcia-Blanco, Timothy J. Robinson, Micah A. Luftig, Raul E. Salinas, Eleonora Forte, Nicholas J. Homa
Publikováno v:
Journal of Virology. 87:12291-12301
Oncogenic viruses promote cell proliferation through the dramatic reorganization of host transcriptomes. In addition to regulating mRNA abundance, changes in mRNA isoform usage can have a profound impact on the protein output of the transcriptome. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ff9f632d14042f65907744fcdfb94a
https://doi.org/10.1128/jvi.02464-13
https://doi.org/10.1128/jvi.02464-13
Autor:
Raul E. Salinas, Jason P. Tourigny, Alexander M. Price, Sandeep S. Dave, Eleonora Forte, Micah A. Luftig
Publikováno v:
Journal of Virology. 86:11096-11106
Epstein-Barr virus (EBV) is an oncogenic human herpesvirus that dramatically reorganizes host gene expression to immortalize primary B cells. In this study, we analyzed EBV-regulated host gene expression changes following primary B-cell infection, bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51fb0abdb140d8c705eca1f30fb52af
https://doi.org/10.1128/jvi.01069-12
https://doi.org/10.1128/jvi.01069-12
Autor:
Shaan Puri, Timothy J. Robinson, Micah A. Luftig, Eleonora Forte, Raul E. Salinas, Mariano A. Garcia-Blanco, Matthew S. Marengo
Publikováno v:
RNA. 18:1435-1445
The key postulate that one gene encodes one protein has been overhauled with the discovery that one gene can generate multiple RNA transcripts through alternative mRNA processing. In this study, we describe SplicerEX, a novel and uniquely motivated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a1d8629316f3542a402d42d802eec8
https://doi.org/10.1261/rna.033621.112
https://doi.org/10.1261/rna.033621.112
Autor:
Sarah D. Linnstaedt, Raul E. Salinas, Christina Chang, Micah A. Luftig, Eleonora Forte, Ting Zhou, Sandeep S. Dave, Dereje D. Jima, Eva Gottwein, Qi-Jing Li, Cassandra L. Jacobs
Epstein-Barr virus (EBV) infection of primary human B cells drives their indefinite proliferation into lymphoblastoid cell lines (LCLs). B cell immortalization depends on expression of viral latency genes, as well as the regulation of host genes. Giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff9087c44575fc067cc208d3699cec9
https://europepmc.org/articles/PMC3393554/
https://europepmc.org/articles/PMC3393554/