Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Raul Chavez-Valdez"'
Autor:
Pritika Parmar, Harisa Spahic, Charles Lechner, Mark St. Pierre, Katherine Carlin, Michael Nugent, Raul Chavez-Valdez
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106722- (2024)
Postnatal critical periods of synaptic plasticity (CPsp) are characterized by profound neural network refinement, which is shaped by synaptic activity and sculpted by maturation of the GABAergic network. Even after therapeutic hypothermia (TH), neona
Externí odkaz:
https://doaj.org/article/f6acbf7da1034ad2b81343d74d05e786
Autor:
Leslie Doucette, Victoria Turnbill, Katherine Carlin, Andrew Cavanagh, Benjamin Sollinger, Nazli Kuter, Debra L. Flock, Shenandoah Robinson, Raul Chavez-Valdez, Lauren Jantzie, Lee J. Martin, Frances J. Northington
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106629- (2024)
Hypoxic-ischemic encephalopathy (HIE) in neonates causes mortality and neurologic morbidity, including poor cognition with a complex neuropathology. Injury to the cholinergic basal forebrain and its rich innervation of cerebral cortex may also drive
Externí odkaz:
https://doaj.org/article/035c2c747a734edb8ecad5c525f26ffc
Autor:
Kengo Onda, Eva Catenaccio, Jill Chotiyanonta, Raul Chavez-Valdez, Avner Meoded, Bruno P. Soares, Aylin Tekes, Harisa Spahic, Sarah C. Miller, Sarah-Jane Parker, Charlamaine Parkinson, Dhananjay M. Vaidya, Ernest M. Graham, Carl E. Stafstrom, Allen D. Everett, Frances J. Northington, Kenichi Oishi
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Hypoxic–ischemic encephalopathy (HIE) is the most common cause of neonatal acquired brain injury. Although conventional MRI may predict neurodevelopmental outcomes, accurate prognostication remains difficult. As diffusion tensor imaging (DTI) may p
Externí odkaz:
https://doaj.org/article/bfc3571b19134a858756427593fb1b46
Autor:
Mark St. Pierre, Sarah Ann Duck, Michelle Nazareth, Camille Fung, Lauren L. Jantzie, Raul Chavez-Valdez
Publikováno v:
Life, Vol 13, Iss 4, p 899 (2023)
Microglia morphological studies have been limited to the process of reviewing the most common characteristics of a group of cells to conclude the likelihood of a “pathological” milieu. We have developed an Imaris-software-based analytical pipelin
Externí odkaz:
https://doaj.org/article/93765f50d5944b3dabe9dbb2c86d925f
Autor:
Raul Chavez-Valdez, Sarah Miller, Harisa Spahic, Dhananjay Vaidya, Charlamaine Parkinson, Barbara Dietrick, Sandra Brooks, Gwendolyn J. Gerner, Aylin Tekes, Ernest M. Graham, Frances J. Northington, Allen D. Everett
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: To determine the changes due to therapeutic hypothermia (TH) exposure in the strength of association between traditional clinical and biochemical indicators of severity of neonatal hypoxic-ischemic encephalopathy (HIE) and serum biomarkers
Externí odkaz:
https://doaj.org/article/eba8d14dd5b8404081ffe7d7dac261bf
Autor:
Xiuyun Liu, Aylin Tekes, Jamie Perin, May W. Chen, Bruno P. Soares, An N. Massaro, Rathinaswamy B. Govindan, Charlamaine Parkinson, Raul Chavez-Valdez, Frances J. Northington, Ken M. Brady, Jennifer K. Lee
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Dysfunctional cerebrovascular autoregulation may contribute to neurologic injury in neonatal hypoxic-ischemic encephalopathy (HIE). Identifying the optimal mean arterial blood pressure (MAPopt) that best supports autoregulation could help identify he
Externí odkaz:
https://doaj.org/article/e46c6c4ccfe441e8b143e2895d312da2
Autor:
Charles R. Lechner, Melanie A. McNally, Mark St. Pierre, Ryan J. Felling, Frances J. Northington, Carl E. Stafstrom, Raul Chavez-Valdez
Publikováno v:
Neurobiology of Disease, Vol 148, Iss , Pp 105222- (2021)
Since neonatal hypoxia-ischemia (HI) disrupts the hippocampal (Hp) GABAergic network in the mouse and Hp injury in this model correlates with flurothyl seizure susceptibility only in male mice, we hypothesized that GABAergic disruption correlates wit
Externí odkaz:
https://doaj.org/article/d9af2674c27c4db193326fb607f148ea
Autor:
Raul Chavez-Valdez, Amin Mottahedin, Linnea Stridh, Tracylyn R. Yellowhair, Lauren L. Jantzie, Frances J. Northington, Carina Mallard
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Toll-like receptor (TLR)3 activation during the neonatal period produces responses linked to the origins of neuropsychiatric disorders. Although there is sexual dimorphism in neuropsychiatric disorders, it is unknown if brain responses to TLR3 activa
Externí odkaz:
https://doaj.org/article/cb6ccd6aaa3044deb45f2e4cd322c615
Autor:
Jennifer C Burnsed, Raul Chavez-Valdez, Mir Shanaz Hossain, Kalpashri Kesavan, Lee J Martin, Jiangyang Zhang, Frances J Northington
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118889 (2015)
Externí odkaz:
https://doaj.org/article/c6a258d803b543439ba903408c78d8e3
Publikováno v:
Neurology Research International, Vol 2012 (2012)
Despite the introduction of therapeutic hypothermia, neonatal hypoxic ischemic (HI) brain injury remains a common cause of developmental disability. Development of rational adjuvant therapies to hypothermia requires understanding of the pathways of c
Externí odkaz:
https://doaj.org/article/12c53e784f354f7bb5d142ea7d372138