NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia

Autor: Carolina Hassibe Thomé, Germano Aguiar Ferreira, Diego Antonio Pereira-Martins, Guilherme Augusto dos Santos, César Alexander Ortiz, Lucas Eduardo Botelho de Souza, Lays Martins Sobral, Cleide Lúcia Araújo Silva, Priscila Santos Scheucher, Cristiane Damas Gil, Andréia Machado Leopoldino, Douglas R. A. Silveira, Juan L. Coelho-Silva, Fabíola Traina, Luisa C. Koury, Raul A. M. Melo, Rosane Bittencourt, Katia Pagnano, Ricardo Pasquini, Elenaide C. Nunes, Evandro M. Fagundes, Ana Beatriz F. Gloria, Fábio Rodrigues Kerbauy, Maria de Lourdes Chauffaille, Armand Keating, Martin S. Tallman, Raul C. Ribeiro, Richard Dillon, Arnold Ganser, Bob Löwenberg, Peter Valk, Francesco Lo-Coco, Miguel A. Sanz, Nancy Berliner, Vitor Marcel Faça, Eduardo M. Rego

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)

Abstract Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute promyelocytic leukemia (APL), NTAL depletion from lipid rafts decreases cell viability throu

Externí odkaz: https://doaj.org/article/1687378c1dd345e09a5c08f24c483459

Freqüência do fator V Leiden em indivíduos sob investigação de trombofilia, Recife, Pernambuco, Brasil Frequency of factor V Leiden in individuals under thrombophilia investigation, Recife, Pernambuco, Brazil

Autor: Catarina P. S. Ramos, Júlia F. Campos, Fárida C. B. C. Melo, Washington B. das Neves, Maria E. dos Santos, Fátima A. Araújo, Raul A. M. Melo

Publikováno v: Revista Brasileira de Hematologia e Hemoterapia, Vol 28, Iss 2, Pp 131-134 (2006)

As tromboses são eventos de etiopatogênese multifatorial resultantes da interação de fatores genéticos e ambientais, constituindo na atualidade uma das causas mais comuns de morbimortalidade. Uma mutação de ponto no fator V da coagulação, o

Externí odkaz: https://doaj.org/article/c00d9a984a374574b80355d0923ab36a

The experience of the International Consortium on Acute Promyelocytic Leukemia in monitoring minimal residual disease in acute promyelocytic leukaemia

Autor: David Grimwade, Antonio R. Lucena-Araujo, Katia B Pagnano, Rosane Bittencourt, Eduardo Magalhães Rego, Francesco Lo-Coco, Ana Paula Alencar de Lima Lange, Miguel A. Sanz, Evandro M. Fagundes, Ana Carolina Stocco de Lima, Rafael H. Jacomo, Maria de Lourdes Lopes Ferrari Chauffaille, Raul A. M. Melo, Ricardo Pasquini, Carlos S. Chiattone

Publikováno v: BRITISH JOURNAL OF HAEMATOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b0daa37c6073ef52edf5fc348969f4
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7847

Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia

Autor: Raul A. M. Melo, Pedro L Franca-Neto, Arnold Ganser, Raul C. Ribeiro, Martin S. Tallman, Eduardo Magalhães Rego, Maria de Lourdes Lopes Ferrari Chauffaille, Miguel A. Sanz, Diego A Pereira-Martins, Luisa C A Koury, David Grimwade, Rosane Bittencourt, Virginia Mara De Deus Wagatsuma, Ricardo Pasquini, Nancy Berliner, Stanley L. Schrier, Katia B Pagnano, Antonio R. Lucena-Araujo, Carlos S. Chiattone, Bob Löwenberg, Evandro M. Fagundes, Juan L Coelho-Silva, Francesco Lo-Coco

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Although overexpression of the brain and acute leukemia, cytoplasmic (BAALC) gene is associated with primary resistant disease and shorter relapse-free, disease-free, and overall survival in different subsets of acute myeloid leukemia (AML), little i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9de5a2424bb8b3bfbc85eb21f85d4a8

All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies

Autor: Miguel A, Sanz, Pau, Montesinos, Haesook T, Kim, Guillermo J, Ruiz-Argüelles, María S, Undurraga, María R, Uriarte, Lem, Martínez, Rafael H, Jacomo, Homero, Gutiérrez-Aguirre, Raul A M, Melo, Rosane, Bittencourt, Ricardo, Pasquini, Katia, Pagnano, Evandro M, Fagundes, Edo, Vellenga, Alexandra, Holowiecka, Ana J, González-Huerta, Pascual, Fernández, Javier, De la Serna, Salut, Brunet, Elena, De Lisa, José, González-Campos, José M, Ribera, Isabel, Krsnik, Arnold, Ganser, Nancy, Berliner, Raul C, Ribeiro, Francesco, Lo-Coco, Bob, Löwenberg, Eduardo M, Rego, E, de Lisa

Publikováno v: ANNALS OF HEMATOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Annals of Hematology, 94(8), 1347-1356. SPRINGER
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Annals of Hematology, 94(8), 1347-1356. Springer-Verlag

Front-line treatment of acute promyelocytic leukaemia (APL) consists of all-trans retinoic acid (ATRA) and anthracycline-based chemotherapy. In this setting, a comparison of idarubicin and daunorubicin has never been carried out. Two similar clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5f141531b801e602097a47d685fe7c
https://pubmed.ncbi.nlm.nih.gov/25975975