Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rauf Ahmad Najar"'
Autor:
Zahra Mahamed, Mohammad Shadab, Rauf Ahmad Najar, Michelle Warren Millar, Jashandeep Bal, Traci Pressley, Fabeha Fazal
Publikováno v:
Cells, Vol 13, Iss 1, p 5 (2023)
Earlier studies from our lab identified endoplasmic reticulum (ER) chaperone BiP/GRP78, an important component of MAM, to be a novel determinant of endothelial cell (EC) dysfunction associated with acute lung injury (ALI). Sigma1R (Sig1R) is another
Externí odkaz:
https://doaj.org/article/5eea64e8ec274c6799b5505a1a377922
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer and Neurodegenerative diseases are one of the most dreadful diseases to cure and chemotherapy has found a prime place in cancerous treatments while as different strategies have been tested in neurodegenerative diseases as well. However, due to
Externí odkaz:
https://doaj.org/article/b602efa361b34921afdc30ddc90d29af
Autor:
Aveksha Sharma, Shani Mistriel-Zerbib, Rauf Ahmad Najar, Eden Engal, Mercedes Bentata, Nadeen Taqatqa, Sara Dahan, Klil Cohen, Shiri Jaffe-Herman, Ophir Geminder, Mai Baker, Yuval Nevo, Inbar Plaschkes, Gillian Kay, Yotam Drier, Michael Berger, Maayan Salton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a93ecf1d37ae7a8ebb3bd283b69197
https://doi.org/10.15252/rc.2023611290
https://doi.org/10.15252/rc.2023611290
Autor:
Aveksha Sharma, Shani Mistriel-Zerbib, Rauf Ahmad Najar, Eden Engal, Mercedes Bentata, Nadeen Taqatqa, Sara Dahan, Klil Cohen, Shiri Jaffe-Herman, Ophir Geminder, Mai Baker, Yuval Nevo, Inbar Plaschkes, Gillian Kay, Yotam Drier, Michael Berger, Maayan Salton
T-cell acute lymphoblastic leukemia (T-ALL) protein 1 (TAL1) is a central transcription factor in hematopoiesis. The timing and level of TAL1 expression orchestrate the differentiation to specialized blood cells and its overexpression is a common cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f596b0a348323cff93979f16fae4d754
https://doi.org/10.1101/2022.11.30.518304
https://doi.org/10.1101/2022.11.30.518304
Autor:
Simmi Sharma, Abid Hamid, Neena Capalash, Bhahwal Ali Shah, Mudassier Ahmad, Mohammad Imran Khan, Nawab John Dar, Dilip M. Mondhe, Javeed Ahmad Bhat, Mubashir Javed Mintoo, Rauf Ahmad Najar
Background: Acute promyelocytic leukemia (APL) and acute lymphoblastic leukaemia (ALL) are often presented with loss of H4K16 monoacetylation (ac) and H4K20 trimethylation (3Me) due to increased activity of Class I HDAC’s. In the current study we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1032a310cb6739adb43ecaf0904d01e3
https://doi.org/10.21203/rs.3.rs-56819/v1
https://doi.org/10.21203/rs.3.rs-56819/v1
Autor:
Beenish Rahat, Jyotdeep Kaur, Javeed Ahmad Bhat, Jaspreet Kaur, Ajai Prakash Gupta, Abid Hamid, Nawab John Dar, Nissar Ahmad Wani, Rauf Ahmad Najar
Publikováno v:
The Journal of Nutritional Biochemistry. 53:121-132
The present study has been designed to determine the effect of folate modulation (deficiency/supplementation) with aging on the promoter methylation of tumor suppressor and proto-oncogenes to understand the underlying mechanism of epigenetic alterati
Publikováno v:
Prenatal Diagnosis. 37:133-143
Objectives The objective of the study is to investigate the role of methylation levels at promoter regions of placental vascularization genes (VEGF, EGFR, and c-jun) in pathogenesis and diagnosis of placental disorders. Methods We analyzed DNA and hi
Autor:
Gillian Kay, Mai Baker, Klil Cohen, Sarah Araten, Sara Dahan, Alona Rabner, Ahmad Siam, Yael Mandel-Gutfreund, Maayan Salton, Gal Regev, Yuval Nevo, Leah Amit, Mercedes Bentata, Rauf Ahmad Najar
Publikováno v:
RNA
Splicing of precursor mRNA (pre-mRNA) is an important regulatory step in gene expression. Recent evidence points to a regulatory role of chromatin-related proteins in alternative splicing regulation. Using an unbiased approach, we have identified the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05214e8a94b18c7645ec53016bf6e9e1
https://europepmc.org/articles/PMC6573785/
https://europepmc.org/articles/PMC6573785/
Autor:
Aashiq Hussain, Abid Hamid, Jyotdeep Kaur, Rauf Ahmad Najar, Shilpa Thakur, Jaspreet Kaur, Beenish Rahat
Publikováno v:
Molecular Nutrition & Food Research. 60:1501-1513
Scope The present study was designed to identify the molecular mechanism of folate modulation and aging on aberrant liver folate transporter system. Methods and results An in vivo rat model was used, in which weanling, young and adult rats were given
Publikováno v:
The Journal of Nutritional Biochemistry. 26:1084-1094
Folic acid is an essential micronutrient, deficiency of which can lead to disturbance in various metabolic processes of cell. Folate transport across intestine occurs via the involvement of specialized folate transporters viz. proton coupled folate t