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MicroRNA-200c Attenuates the Tumor-Infiltrating Capacity of Macrophages

Autor: Raue, Rebecca, Frank, Ann Christin, Fuhrmann, Dominik C., Cruz Ojeda, Patricia de la, Rösser, Silvia, Bauer, Rebekka, Brüne, Bernhard

Macrophages constitute a major part of the tumor-infiltrating immune cells. Within the tumor microenvironment, they acquire an alternatively activated, tumor-supporting phenotype. Factors released by tumor cells are crucial for the recruitment of tum

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MicroRNA - a tumor trojan horse for tumor-associated macrophages

Autor: Syed, Shahzad Nawaz, Frank, Ann-Christin, Raue, Rebecca, Brüne, Bernhard

MicroRNAs (miRs) significantly contribute to the regulation of gene expression, by virtue of their ability to interact with a broad, yet specific set of target genes. MiRs are produced and released by almost every cell type and play an important role

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http://publikationen.ub.uni-frankfurt.de/files/51650/cells-08-01482-v2.pdf

MicroRNA-200c Attenuates the Tumor-Infiltrating Capacity of Macrophages.

Autor: Raue R; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Frank AC; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Fuhrmann DC; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., de la Cruz-Ojeda P; Institute of Biomedicine of Seville (IBiS), Hospital University 'Virgen del Rocío'/CSIC/University of Seville, 41013 Seville, Spain., Rösser S; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Bauer R; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Cardamone G; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Weigert A; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt, 60590 Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe-University Frankfurt, 60596 Frankfurt, Germany., Syed SN; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Schmid T; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany., Brüne B; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt, 60590 Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe-University Frankfurt, 60596 Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology, 60596 Frankfurt, Germany.

Publikováno v: Biology [Biology (Basel)] 2022 Feb 22; Vol. 11 (3). Date of Electronic Publication: 2022 Feb 22.