Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rauan Sagit"'
Publikováno v:
Journal of Structural Biology; Vol 179
Particularly in higher eukaryotes, some protein domains are found in tandem repeats, performing broad functions often related to cellular organization. For instance, the eukaryotic protein filamin interacts with many proteins and is crucial for the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1857463b465b60c2b382ee176f3b21a
Publikováno v:
Journal of Molecular Biology. 402:38-51
Protein domain repeats are common in proteins that are central to the organization of a cell, in particular in eukaryotes. They are known to evolve through internal tandem duplications. However, the understanding of the underlying mechanisms is incom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79041b39514a29482bbbe91eead47738
https://doi.org/10.1016/j.jmb.2010.07.011
https://doi.org/10.1016/j.jmb.2010.07.011
Publikováno v:
Molecular Biology and Evolution; Vol 30
Proteins evolve not only through point mutations but also by insertion and deletion events, which affect the length of the protein. It is well known that such indel events most frequently occur in surface-exposed loops. However, detailed analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c25a9b275ad8be0e413f1c0b2ac4482
https://pubmed.ncbi.nlm.nih.gov/24037790
https://pubmed.ncbi.nlm.nih.gov/24037790
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics; Vol 1834
Proteins evolve through point mutations as well as by insertions and deletions (indels). During the last decade it has become apparent that protein regions that do not fold into three-dimensional structures, i.e. intrinsically disordered regions, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720f4ce4d76528bf357bd9157ae6e967
https://pubmed.ncbi.nlm.nih.gov/23333420
https://pubmed.ncbi.nlm.nih.gov/23333420