Chronic administration of recombinant IL-6 upregulates lipogenic enzyme expression and aggravates high-fat-diet-induced steatosis in IL-6-deficient mice

Autor: Juan Suárez, Ana Luisa Gavito, Miguel Romero-Cuevas, Sergio Arrabal, Francisco Javier Pavón, Dolores Bautista, Elena Baixeras, Antonia Serrano, Juan Decara, Margarita Vida, Fernando Rodríguez de Fonseca

Publikováno v: Disease Models & Mechanisms, Vol 8, Iss 7, Pp 721-731 (2015)
Disease Models & Mechanisms

Interleukin-6 (IL-6) has emerged as an important mediator of fatty acid metabolism with paradoxical effects in the liver. Administration of IL-6 has been reported to confer protection against steatosis, but plasma and tissue IL-6 concentrations are e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311b02778dd0d4a225edf8548a97b7f6
http://dmm.biologists.org/content/8/7/721

PARP inhibition attenuates histopathological lesion in ischemia/reperfusion renal mouse model after cold prolonged ischemia

Autor: T. Caballero, Mª Dolores Rodríguez-Martínez, F. Javier Oliver, Andreína Peralta, Raimundo M. G. del Moral, Antonio Osuna, Mercedes Caba-Molina, Francisco O'Valle, Pedro Hernández-Cortés, D. Aguilar, José Aneiros-Fernández, Raimundo G. del Moral, Mercedes Gómez-Morales, Pablo Galindo-Moreno

Publikováno v: The Scientific World Journal
Digibug. Repositorio Institucional de la Universidad de Granada
instname
The Scientific World Journal, Vol 2013 (2013)

We test the hypothesis that PARP inhibition can decrease acute tubular necrosis (ATN) and other renal lesions related to prolonged cold ischemia/reperfusion (IR) in kidneys preserved at 4°C in University of Wisconsin (UW) solution. Material and Meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e776376589d04a1ed06cbf7fcf86379
https://pubmed.ncbi.nlm.nih.gov/24319370

Human MAMLD1 gene variations seem not sufficient to explain a 46,XY DSD phenotype

Autor: Camats Tarruella, Núria, Fernández Cancio, Mónica, Audí, Laura, Mullis, Primus E., Moreno, Francisca, González Casado, Isabel, López-Siguero, Juan Pedro, Corripio, Raquel, Bermúdez de la Vega, José Antonio, Blanco, José Antonio, Flück, Christa E., Universitat Autònoma de Barcelona

Publikováno v: PLoS One
PLoS ONE
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Camats Tarruella, Núria; Fernández-Cancio, Mónica; Audí, Laura; Mullis, Primus-Eugen; Moreno, Francisca; González Casado, Isabel; López-Siguero, Juan Pedro; Corripio, Raquel; Bermúdez de la Vega, José Antonio; Blanco, José Antonio; Flück, Christa Emma (2015). Human MAMLD1 Gene Variations Seem Not Sufficient to Explain a 46,XY DSD Phenotype. PLoS ONE, 10(11), e0142831. Public Library of Science 10.1371/journal.pone.0142831
PLoS ONE, Vol 10, Iss 11, p e0142831 (2015)

Ajuts: Swiss National Science Foundation (320030-146127), the Instituto de Salud Carlos III CIBERER U-712, i the University and Research Management and Evaluation Agency (2009SGR31) MAMLD1 is thought to cause disordered sex development in 46,XY patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b69ae641bdf12c1daf404bc12df341
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142831