Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Ratnesh, Lal"'
Autor:
Abhijith G. Karkisaval, Rowan Hassan, Andrew Nguyen, Benjamin Balster, Faisal Abedin, Ratnesh Lal, Suren A. Tatulian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Amyloid β (Aβ) ion channels destabilize cellular ionic homeostasis, which contributes to neurotoxicity in Alzheimer’s disease. The relative roles of various Aβ isoforms are poorly understood. We use bilayer electrophysiology, AFM imagin
Externí odkaz:
https://doaj.org/article/34b1fdc52ba14d6ab28ab5b80004d6f0
Autor:
Munis Dündar, Adam Mechler, Jean-pierre Alcaraz, Gary Henehan, Satya Prakash, Ratnesh Lal, Donald Martin
Publikováno v:
Erciyes Medical Journal, Vol 42, Iss 4, Pp 370-379 (2020)
Nanomedicine technologies seem to play an increasing role in modern medicine. Although there are many challenges, it is important to consider emerging technologies that may impact nanomedicine. To establish a rational basis for such consideration in
Externí odkaz:
https://doaj.org/article/41f309ef1bdf4f1881c28ba202704aeb
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272329 (2022)
Colloidal particles constitute a substantial fraction of organic matter in the global ocean and an abundant component of the organic matter interacting with bacterial surfaces. Using E. coli ribosomes as model colloidal particles, we applied high-res
Externí odkaz:
https://doaj.org/article/354aad6aa6c942c8bad8936606035a95
Autor:
Sindhushree Raghunandan, Srinivasan Ramachandran, Eugene Ke, Yifei Miao, Ratnesh Lal, Zhen Bouman Chen, Shankar Subramaniam
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Endothelial cells (ECs) form the inner lining of blood vessels and are central to sensing chemical perturbations that can lead to oxidative stress. The degree of stress is correlated with divergent phenotypes such as quiescence, cell death, or senesc
Externí odkaz:
https://doaj.org/article/b3b37d0613034721880255336934864e
Autor:
Donald K. Martin, Oscar Vicente, Tommaso Beccari, Miklós Kellermayer, Martin Koller, Ratnesh Lal, Robert S. Marks, Ivana Marova, Adam Mechler, Dana Tapaloaga, Polona Žnidaršič-Plazl, Munis Dundar
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 35, Iss S1, Pp S5-S14 (2021)
Biotechnology is an innovative, interdisciplinary field that impacts many different sectors, including agriculture, veterinary, medicine, pharmaceutical and fine chemicals production. It is emerging as one of the leading technologies for the transiti
Externí odkaz:
https://doaj.org/article/1059d1bd2a624fe49ca7d65ea916ef2e
Autor:
Ana Martinez Hernandez, Hendrik Urbanke, Alan L Gillman, Joon Lee, Sergey Ryazanov, Hope Y Agbemenyah, Eva Benito, Gaurav Jain, Lalit Kaurani, Gayane Grigorian, Andrei Leonov, Nasrollah Rezaei‐Ghaleh, Petra Wilken, Fernando Teran Arce, Jens Wagner, Martin Fuhrmann, Mario Caruana, Angelique Camilleri, Neville Vassallo, Markus Zweckstetter, Roland Benz, Armin Giese, Anja Schneider, Martin Korte, Ratnesh Lal, Christian Griesinger, Gregor Eichele, Andre Fischer
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 32-47 (2017)
Abstract Alzheimer's disease is a devastating neurodegenerative disease eventually leading to dementia. An effective treatment does not yet exist. Here we show that oral application of the compound anle138b restores hippocampal synaptic and transcrip
Externí odkaz:
https://doaj.org/article/c508142ad7ed44dda436f67105c1fa85
Autor:
Mengmeng Liu, Qian Li, Le Liang, Jiang Li, Kun Wang, Jiajun Li, Min Lv, Nan Chen, Haiyun Song, Joon Lee, Jiye Shi, Lihua Wang, Ratnesh Lal, Chunhai Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The interaction of nanoparticles intracellularly has been investigated widely but the mechanisms of such interactions are not fully understood. Here, the authors utilize a semi-quantitative technique to assess the intracellular transportation and clu
Externí odkaz:
https://doaj.org/article/5a4addc3b27d4845b8122eee48f284ad
Autor:
Shyam S. Mohapatra, Robert D. Frisina, Subhra Mohapatra, Kevin B. Sneed, Eleni Markoutsa, Tao Wang, Rinku Dutta, Ratka Damnjanovic, Manh-Huong Phan, Daniel J. Denmark, Manas R. Biswal, Andrew R. McGill, Ryan Green, Mark Howell, Payal Ghosh, Alejandro Gonzalez, Nadia Tasnim Ahmed, Brittney Borresen, Mitchell Farmer, Melissa Gaeta, Krishna Sharma, Christen Bouchard, Danielle Gamboni, Jamie Martin, Bianca Tolve, Mandip Singh, Jack W. Judy, Chenzhong Li, Swadeshmukul Santra, Sylvia Daunert, Elnaz Zeynaloo, Ryan M. Gelfand, Steven Lenhert, Eric S. McLamore, Dong Xiang, Victoria Morgan, Lisa E. Friedersdorf, Ratnesh Lal, Thomas J. Webster, David P. Hoogerheide, Thanh Duc Nguyen, Martin J. D'Souza, Mustafa Çulha, Pierre P. D. Kondiah, Donald K. Martin
Publikováno v:
Applied Sciences, Vol 10, Iss 14, p 4881 (2020)
The burgeoning field of nanotechnology aims to create and deploy nanoscale structures, devices, and systems with novel, size-dependent properties and functions. The nanotechnology revolution has sparked radically new technologies and strategies acros
Externí odkaz:
https://doaj.org/article/49c2ddedbd774f1f99469123e767f109
Publikováno v:
Biophysical journal, vol 120, iss 16
Amyloid-β (Aβ) oligomers are toxic species implicated in Alzheimer's disease (AD). The prevailing hypothesis implicates a major role of membrane-associated amyloid oligomers in AD pathology. Our silica nanobowls (NB) coated with lipid-polymer have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a7f387d4bc181a69bb9d4e3c6b84b1
https://doi.org/10.1016/j.bpj.2021.07.002
https://doi.org/10.1016/j.bpj.2021.07.002
Autor:
Deependra Kumar Ban, Tyler Bodily, Abhijith G. Karkisaval, Yongliang Dong, Shreyam Natani, Anirudh Ramanathan, Armando Ramil, Sunil Srivastava, Prab Bandaru, Gennadi Glinsky, Ratnesh Lal
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 28
We have developed a DNA aptamer-conjugated graphene field-effect transistor (GFET) biosensor platform to detect receptor-binding domain (RBD), nucleocapsid (N), and spike (S) proteins, as well as viral particles of original Severe acute respiratory s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa46e8681a287536e346bf33571593f
https://escholarship.org/uc/item/3z17b51n
https://escholarship.org/uc/item/3z17b51n
