Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ratnam Boopathy"'
Autor:
Chitrambalam Palaniappan, Yarlagadda Udaya Bhaskara Rao, Ratnam Boopathy, Lakshman Narasingha Rao Bhau, Bheeman Sundaran
Publikováno v:
Journal of Bioscience and Bioengineering. 94:93-98
The commercial preparation of purified diphtheria toxoid primarily depends on the effective separation of the toxin from a large culture volume of Corynebacterium diphtheriae vaccine strain. Tangential flow or cross-flow filtration is gaining momentu
Publikováno v:
Journal of Bioscience and Bioengineering. 91:123-128
When stationary culture was replaced by submerged cultivation in a fermentor, a significant increase in the yield of diphtheria toxin in a short cultivation time (less than 48 h as against 7-8 d) was noted. It was found that under optimal conditions