Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ratna Kancana Wolfram"'
Publikováno v:
Medicinal Chemistry Research. 29:926-933
The coupling of acetylated piperazinylamide spacered triterpenoic oleanolic acid and ursolic acid withmetaorparasubstituted carboxylated malachite green analogs gave conjugates10,11,15, and16that were cytotoxic for several human tumor cell lines. Esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b2decd39b6a89f385e1a9b4816330e9
https://doi.org/10.1007/s00044-020-02536-1
https://doi.org/10.1007/s00044-020-02536-1
Autor:
Björn Weber, Lucie Fischer, Ahmed Al-Harrasi, Sophie Hoenke, Ratna Kancana Wolfram, René Csuk
Publikováno v:
Mediterranean Journal of Chemistry, Vol 9, Iss 1, Pp 45-51 (2019)
A small series of substituted cinnamic acid amides was prepared and screened for their cytotoxic activity. As a rather astonishing and unprecedented result, compound 5 holding a triisopropylsilyl (TIPS) protecting group at position 4 of the aromatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda29c8fce17262310332b98dc11e8f4
https://doi.org/10.13171/mjc91190820520rc
https://doi.org/10.13171/mjc91190820520rc
Publikováno v:
Mediterranean Journal of Chemistry. 7:286-293
Oxidation of 2,3-dehydro-11-keto--boswellic acid gave derivatives holding extra hydroxyl groups at positions C-1, C-2 or C-1 and C-9, respectively. The synthesis of 2,3-dehydro-1,9-dihydroxy-11-keto--boswellic acid represents the first partial-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91656c6bcb6b01e7d310e7e4aae595ac
https://doi.org/10.13171/mjc74181121-csuk
https://doi.org/10.13171/mjc74181121-csuk
Targeting mitochondria: Esters of rhodamine B with triterpenoids are mitocanic triggers of apoptosis
Publikováno v:
European Journal of Medicinal Chemistry. 152:21-30
Triterpenoic acids, ursolic acid (1), oleanolic acid (2), glycyrrhetinic acid (3) and betulinic acid (4) were converted into their corresponding methyl 5-8 and benzyl esters 9-12 or benzyl amides 21-24. These derivatives served as starting materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2a373b0453cb014ec57b9975f1bb9a
https://doi.org/10.1016/j.ejmech.2018.04.031
https://doi.org/10.1016/j.ejmech.2018.04.031
Autor:
Ratna Kancana Wolfram, Anja Barthel-Niesen, René Csuk, Ahmed Al-Harrasi, Lucie Heller, Renate Schäfer
Publikováno v:
Mediterranean Journal of Chemistry, Vol 6, Iss 5, Pp 180-190 (2017)
The aim of this study was to prepare 11-keto-b-boswellic acid derivatives modified at C-24 and to evaluate their in vitro cytotoxicity. Acetyl-11-keto-b-boswellic acid (AKBA) was isolated from frankincense and transformed into 11-keto-b-boswellic aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b71333001e009fab0e583849161678
http://medjchem.com/index.php/medjchem/article/view/626
http://medjchem.com/index.php/medjchem/article/view/626
Autor:
Ratna Kancana Wolfram, Anja Barthel-Niesen, René Csuk, Lucie Heller, Ahmed Al-Harrasi, Renate Schäfer
Publikováno v:
Mediterranean Journal of Chemistry, Vol 6, Iss 4, Pp 142-164 (2017)
Beta-boswellic acids are triterpenoids being generic to the plants of genus boswellia. Although they were shown to exhibit different biological activities, the cytotoxic potential of b-boswellic acid derivatives remained by and large unexploited. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc581f07ffadd6f6fe6e1c087411b2e
https://doi.org/10.13171/mjc64/01707151548-csuk
https://doi.org/10.13171/mjc64/01707151548-csuk