Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Ratna B Ray"'
Autor:
Tapas Patra, Keith Meyer, Lizzie Geerling, T Scott Isbell, Daniel F Hoft, James Brien, Amelia K Pinto, Ratna B Ray, Ranjit Ray
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009128 (2020)
Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2 infection, although the mechanism for initiation of a hyper-inflammatory response, and multi-organ damage from viral infection is poorly understood. In this vi
Externí odkaz:
https://doaj.org/article/3a8082e06d9942d88e7c2e4965d699ec
Autor:
Ananthi Rajamoorthi, Shubham Shrivastava, Robert Steele, Pratibha Nerurkar, Juan G Gonzalez, Susan Crawford, Mark Varvares, Ratna B Ray
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78006 (2013)
Head and neck squamous cell carcinoma (HNSCC) remains difficult to treat, and despite of advances in treatment, the overall survival rate has only modestly improved over the past several years. Thus, there is an urgent need for additional therapeutic
Externí odkaz:
https://doaj.org/article/a10591f04ad14ddd9d832721aff2c9bc
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62581 (2013)
Chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality globally, and often leads to end-stage liver disease. The DNA damage checkpoint pathway induces cell cycle arrest for repairing DNA in response to DNA damage.
Externí odkaz:
https://doaj.org/article/b4fa3739b67844a89f995da93fed86a0
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3384 (2008)
MBP-1 acts as a general transcriptional repressor. Overexpression of MBP-1 induces cell death in a number of cancer cells and regresses tumor growth. However, the function of endogenous MBP-1 in normal cell growth regulation remains unknown. To unrav
Externí odkaz:
https://doaj.org/article/ba2ed9fa47c34d26a62d02291cc5e0b2
Publikováno v:
International journal of molecular sciences. 23(17)
Alcohol is the one of the major causes of liver diseases and promotes liver cirrhosis and hepatocellular carcinoma (HCC). In hepatocytes, alcohol is converted to acetaldehyde, which causes hepatic steatosis, cellular apoptosis, endoplasmic reticulum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3362d2ae114ca23ae923deb24ae1f7ed
https://pubmed.ncbi.nlm.nih.gov/36077080
https://pubmed.ncbi.nlm.nih.gov/36077080
Publikováno v:
mBio. 13
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces inflammatory response, cytokine storm, venous thromboembolism, coagulopathy, and multiple organ damage. Resting endothelial cells prevent coagulation, control blood flow,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badd3490a216b042d91f60a2a91bca8e
https://doi.org/10.1128/mbio.00951-22
https://doi.org/10.1128/mbio.00951-22
Autor:
Subhayan Sur, Ratna B. Ray
Publikováno v:
The FEBS Journal. 289:3011-3023
Whole genome sequencing and transcriptome analysis revealed more than 90% of the human genome transcribes non-coding RNAs including long non-coding RNAs (lncRNAs). From the beginning of the 21st century, lncRNAs have gained widespread attention as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f1d46ddf794e490e5315f8e7b73dc6
https://doi.org/10.1111/febs.15876
https://doi.org/10.1111/febs.15876
Autor:
Tapas Patra, David M. Cunningham, Keith Meyer, Karoly Toth, Ratna B. Ray, Andras Heczey, Ranjit Ray
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy.
Overexpression of Lin28 is detected in various cancers with involvement in the self-renewal process and cancer stem cell generation. In the present study, we evaluated how the Lin28 axis plays an immune-protective role for tumor initiating cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdf28c0389aef4daa9a8a42e77500ac
https://pubmed.ncbi.nlm.nih.gov/36609146
https://pubmed.ncbi.nlm.nih.gov/36609146
Autor:
Subhayan, Sur, Ratna B, Ray
Publikováno v:
Journal of cancer metastasis and treatment
Oral squamous cell carcinoma (OSCC) is one of the common lethal malignancies which is increasing rapidly in the world. Increasing risks from alcohol and tobacco habits, lack of early detection markers, lack of effective chemotherapeutic agents, recur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eeac49c3573f9f138366436695370b7b
https://pubmed.ncbi.nlm.nih.gov/34765739
https://pubmed.ncbi.nlm.nih.gov/34765739
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-8 (2021)
Cell Death & Disease
Cell Death & Disease
Hepatocellular carcinoma (HCC) is one of the most common malignancy-related deaths. p53 mutation in HCC associates with worse clinicopathologic features including therapeutic limitation. A combination of targeted therapy may have some advantages. Akt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40faf1ec37c85af5abe924f3a7c5862
https://doi.org/10.1038/s41419-021-04371-7
https://doi.org/10.1038/s41419-021-04371-7