Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Ratikan, A."'
Autor:
Dörthe Schaue, Ewa D. Micewicz, Josephine A. Ratikan, Keisuke S. Iwamoto, Erina Vlashi, J. Tyson McDonald, William H. McBride
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1649 (2022)
Nuclear factor erythroid 2-related factor 2 (NRF2) is recognized as a master transcription factor that regulates expression of numerous detoxifying and antioxidant cytoprotective genes. In fact, models of NRF2 deficiency indicate roles not only in re
Externí odkaz:
https://doaj.org/article/d93c14d74c3a4a43a4f52aa740921de6
Autor:
Ewa D. Micewicz, Robert D. Damoiseaux, Gang Deng, Adrian Gomez, Keisuke S. Iwamoto, Michael E. Jung, Christine Nguyen, Andrew J. Norris, Josephine A. Ratikan, Piotr Ruchala, James W. Sayre, Dörthe Schaue, Julian P. Whitelegge, William H. McBride
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We previously reported several vignettes on types and classes of drugs able to mitigate acute and, in at least one case, late radiation syndromes in mice. Most of these had emerged from high throughput screening (HTS) of bioactive and chemical drug l
Externí odkaz:
https://doaj.org/article/51771cf263924ecca3296a531a0d3deb
Akademický článek
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Autor:
Claude J Rogers, Agnes I Lukaszewicz, Jason Yamada-Hanff, Ewa D Micewicz, Josephine A Ratikan, Mark A Starbird, Thomas A Miller, Christine Nguyen, Jason T Lee, Tove Olafsen, Keisuke S Iwamoto, William H McBride, Dörthe Schaue, Naresh Menon
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232411 (2020)
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonary and cardiac damage. Sporadic in nature, late complications tend to be difficult to predict, which prompted this investigation into identifying non-i
Externí odkaz:
https://doaj.org/article/9ef236df45954e98bbb80c111b9106d1
Publikováno v:
In Cancer Letters 28 November 2015 368(2):238-245
Autor:
William H. McBride, Dörthe Schaue, Sandra Demaria, Begoña Comin-Anduix, John A. Glaspy, Sara Hurvitz, James W. Sayre, Kym F. Faull, Lin Hwang, Carol Felix, Josephine A. Ratikan, Mike W. Xie, Xiaochun Li, Judith D. Goldberg, Sylvia Adams, Percy Lee, Silvia C. Formenti
Purpose: This study examined the feasibility, efficacy (abscopal effect), and immune effects of TGFβ blockade during radiotherapy in metastatic breast cancer patients.Experimental Design: Prospective randomized trial comparing two doses of TGFβ blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee4ce866a1caa3bb3db4097bbf93b9f
https://doi.org/10.1158/1078-0432.c.6527234.v1
https://doi.org/10.1158/1078-0432.c.6527234.v1
Autor:
William H. McBride, Dörthe Schaue, Sandra Demaria, Begoña Comin-Anduix, John A. Glaspy, Sara Hurvitz, James W. Sayre, Kym F. Faull, Lin Hwang, Carol Felix, Josephine A. Ratikan, Mike W. Xie, Xiaochun Li, Judith D. Goldberg, Sylvia Adams, Percy Lee, Silvia C. Formenti
Supplementary Table S1. Antibodies and dextramers used for flow cytometric analysis Supplementary Table S2. Patients with one or more treatment positively-related (maximum grade possible, probable, definite) AEs by treatment arm Supplementary Table S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cea5186a1de67faa5d4659a7447e170
https://doi.org/10.1158/1078-0432.22469360.v1
https://doi.org/10.1158/1078-0432.22469360.v1
Autor:
William H. McBride, Lynn Hlatky, Heather Szelag, Josephine Ratikan, Lorenza Della Donna, Chann Lagadec, Tiffany M. Phillips, Erina Vlashi, Andrew J. Norris, Kwanghee Kim, J. Tyson McDonald
Supplementary Figure 2 from Ionizing Radiation Activates the Nrf2 Antioxidant Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5058f45d439767b27cc1f477b524b728
https://doi.org/10.1158/0008-5472.22384169.v1
https://doi.org/10.1158/0008-5472.22384169.v1
Autor:
William H. McBride, Lynn Hlatky, Heather Szelag, Josephine Ratikan, Lorenza Della Donna, Chann Lagadec, Tiffany M. Phillips, Erina Vlashi, Andrew J. Norris, Kwanghee Kim, J. Tyson McDonald
Supplementary Figure Legends 1-4 from Ionizing Radiation Activates the Nrf2 Antioxidant Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffbcfad732700a4f363cd1350934d31
https://doi.org/10.1158/0008-5472.22384160.v1
https://doi.org/10.1158/0008-5472.22384160.v1
Autor:
William H. McBride, Lynn Hlatky, Heather Szelag, Josephine Ratikan, Lorenza Della Donna, Chann Lagadec, Tiffany M. Phillips, Erina Vlashi, Andrew J. Norris, Kwanghee Kim, J. Tyson McDonald
The transcription factor NF-E2-related factor 2 (Nrf2) binds the antioxidant DNA response element (ARE) to activate important cellular cytoprotective defense systems. Recently several types of cancers have been shown to overexpress Nrf2, but its role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1a2a5520ed4942debc34ddecaba0783
https://doi.org/10.1158/0008-5472.c.6500792
https://doi.org/10.1158/0008-5472.c.6500792