Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rati, Fotedar"'
Autor:
Michael Howell, Robert L. Margolis, Justin J Choi, Arun Fotedar, Howard Brickner, Céline DerMardirossian, Andreas Panopoulos, Daniel Miller, Rati Fotedar, Jean-Michel Saffin, Violaine D. Delorme-Walker
Publikováno v:
The Journal of Cell Biology
WISp39 associates with Hsp90, Coronin 1B, and Slingshot phosphatase to regulate Cofilin activation and Arp2/3 complex localization at the leading edge of migrating cells.
We previously identified Waf1 Cip1 stabilizing protein 39 (WISp39) as a bi
We previously identified Waf1 Cip1 stabilizing protein 39 (WISp39) as a bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e236c8bb0c2ab3553f77346d5b0ac380
https://doi.org/10.1083/jcb.201410095
https://doi.org/10.1083/jcb.201410095
Autor:
Mark A. Sussman, Cristina Pacios-Bras, Andreas Panopoulos, Robert L. Margolis, Mythili Yenjerla, Justin J Choi, Rati Fotedar
Publikováno v:
Molecular Biology of the Cell
Induction of tetraploidy through cleavage failure induces G1 arrest and senescence in primary mammalian cells but not in immortal cells. Induction of senescence occurs without DNA damage, and the capacity to become senescent appears to be a prerequis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfab825c9e1e84c7e6173f6a6d427b49
https://doi.org/10.1091/mbc.e14-03-0844
https://doi.org/10.1091/mbc.e14-03-0844
Autor:
Benjamin P. Tu, Amina T. Tassa, Rati Fotedar, Beth Levine, Rui Zhong, Collin Thomas, Z. H. An, Guanghua Xiao, Daniel J. Klionsky
Publikováno v:
Autophagy. 10:1702-1711
In response to starvation, cells undergo increased levels of autophagy and cell cycle arrest but the role of autophagy in starvation-induced cell cycle arrest is not fully understood. Here we show that autophagy genes regulate cell cycle arrest in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fafaadfee6a74fee9ee042abdd4c7b5a
https://doi.org/10.4161/auto.32122
https://doi.org/10.4161/auto.32122
Publikováno v:
Journal of Biological Chemistry. 286:29531-29539
p21(Waf1/Cip1) protein levels respond to DNA damage; p21 is induced after ionizing radiation, but degraded after UV. p21 degradation after UV is necessary for optimal DNA repair, presumably because p21 inhibits nucleotide excision repair by blocking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda78a12d10b9fc407cf22c2f7398e32
https://doi.org/10.1074/jbc.m111.221341
https://doi.org/10.1074/jbc.m111.221341
Publikováno v:
Cell Cycle. 9:1792-1801
Microtubule targeting drugs are successful in chemotherapy because they indefinitely activate the spindle assembly checkpoint. The spindle assembly checkpoint monitors proper attachment of all kinetochores to microtubules and tension between the kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45bd32eb73068354ccafc5ce72751b5
https://doi.org/10.4161/cc.9.9.11519
https://doi.org/10.4161/cc.9.9.11519
Publikováno v:
Oncogene. 29:1702-1716
Cell cycle controls ensure that DNA replication (S phase) follows mitosis resulting in two precise copies of the genome. A failure of the control mechanisms can result in multiple rounds of DNA replication without cell division. In endoreplication, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c605690f3a8c1a22897a0415d840803
https://doi.org/10.1038/onc.2009.464
https://doi.org/10.1038/onc.2009.464
Autor:
Rati Fotedar, Robert L. Margolis
Publikováno v:
Oncotarget
Cell motility is an actin dependent process requiring the formation and extension of lamellipodia or filopodia, and is absolutely essential for many cellular processes, especially for morphogenesis during development. During lamellipodial extension,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0165b54027bc07a1a83ba64f2094e5
https://pubmed.ncbi.nlm.nih.gov/26257007
https://pubmed.ncbi.nlm.nih.gov/26257007
Autor:
Howard Brickner, Abdelhamid El Khissiin, Valerie Barbier, Brian J. Smith, Isabelle Salles-Passador, Thomas Jascur, Arun Fotedar, Rati Fotedar
Publikováno v:
Molecular Cell. 17:237-249
p21 WAF1/CIP1 , a cyclin-dependent kinase inhibitor and a critical regulator of cell cycle, is controlled transcriptionally by p53-dependent and -independent mechanisms and posttranslationally by the proteasome. We have identified WISp39, a tetratric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fb7aad147426d9f238aacf6b35ef39
https://doi.org/10.1016/j.molcel.2004.11.049
https://doi.org/10.1016/j.molcel.2004.11.049
Autor:
Jérôme Boulaire, Alain Sarasin, Mourad Bendjennat, Rati Fotedar, Arun Fotedar, Valerie Barbier, Thomas Jascur, Howard Brickner
Publikováno v:
Cell. 114:599-610
p53-mediated increase in cyclin-dependent kinase inhibitor p21WAF1 protein is thought to be the major mediator of cell cycle arrest after DNA damage. Previously p21 protein levels have been reported to increase or to decrease after UV irradiation. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e5a428b15882293df4a188d59b4b95
https://doi.org/10.1016/j.cell.2003.08.001
https://doi.org/10.1016/j.cell.2003.08.001
Autor:
Isabelle, Salles-Passador, Anil, Munshi, Dominique, Cannella, Vincent, Pennaneach, Stephane, Koundrioukoff, Michel, Jaquinod, Eric, Forest, Vladimir, Podust, Arun, Fotedar, Rati, Fotedar, Michel, Jacquinod
Publikováno v:
Nucleic Acids Research. 31:5202-5211
Replication factor C (RF-C) complex binds to DNA primers and loads PCNA onto DNA, thereby increasing the processivity of DNA polymerases. We have previously identified a distinct region, domain B, in the large subunit of human RF-C (RF-Cp145) which b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973918f4a57f10dab2e24e881baae18e
https://doi.org/10.1093/nar/gkg692
https://doi.org/10.1093/nar/gkg692