Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Rathnasinghe, A. P."'
Autor:
Raveen Rathnasinghe, Lauren A. Chang, Rebecca Pearl, Sonia Jangra, Amy Aspelund, Alaura Hoag, Soner Yildiz, Ignacio Mena, Weina Sun, Madhumathi Loganathan, Nicholas Alexander Crossland, Hans P. Gertje, Anna Elise Tseng, Sadaf Aslam, Randy A. Albrecht, Peter Palese, Florian Krammer, Michael Schotsaert, Thomas Muster, Adolfo García-Sastre
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Influenza viruses pose a threat to public health as evidenced by severe morbidity and mortality in humans on a yearly basis. Given the constant changes in the viral glycoproteins owing to antigenic drift, seasonal influenza vaccines need to
Externí odkaz:
https://doaj.org/article/dccfdfa0d19945a6be803b54e7f7865b
Autor:
Rodrigo Tapia, Bárbara Brito, Marco Saavedra, Juan Mena, Tamara García-Salum, Raveen Rathnasinghe, Gonzalo Barriga, Karla Tapia, Victoria García, Sergio Bucarey, Yunho Jang, David Wentworth, Montserrat Torremorell, Víctor Neira, Rafael A. Medina
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTNovel H1N2 and H3N2 swine influenza A viruses (IAVs) have recently been identified in Chile. The objective of this study was to evaluate their zoonotic potential. We perform phylogenetic analyses to determine the genetic origin and evolution
Externí odkaz:
https://doaj.org/article/39e1ddb4a2cb427a83234f13a81c6489
Autor:
Michael Cheung, Cheng Chang, Raveen Rathnasinghe, Evan Rossignol, Yunfei Zhang, Annette Ferrari, Harsh Patel, Yanjun Huang, Michelle Sanchez Guillen, Tina Scalzo, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Nedzad Music, Giuseppe Palladino, Yingxia Wen
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Currently licensed influenza vaccines focus immune responses on viral hemagglutinin (HA), while the other major surface glycoprotein neuraminidase (NA) is not tightly controlled in inactivated vaccine formulations despite evidence that anti-
Externí odkaz:
https://doaj.org/article/34eefbdcbdca47e4b9effcc04a79f050
Autor:
Nimasha L. Rathnasinghe, Kotuwegoda G. Kaushani, Praveena S. Rajapakshe, Awanthi De Silva, Randika A. Jayasinghe, Renuka N. Liyanage, Nadeeka D. Tissera, Ruchira N. Wijesena, Gayan Priyadarshana
Publikováno v:
Cosmetics, Vol 11, Iss 5, p 152 (2024)
Nanotechnology has applications in a variety of scientific specialties, encompassing health, technological devices, and now cosmetics under the generic term of nanocosmetics. Due to the improved particle qualities, such as color, transparency, and so
Externí odkaz:
https://doaj.org/article/3afdabe6859b4423ada725da3e02f692
Autor:
Sonia Jangra, Jeffrey J. Landers, Gabriel Laghlali, Raveen Rathnasinghe, Prajakta Warang, Seok-Chan Park, Jessica. J. O’Konek, Gagandeep Singh, Katarzyna W. Janczak, Adolfo García-Sastre, Nandini Arya, Dilara Karadag, James R. Baker, Michael Schotsaert, Pamela T. Wong
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Multiple FDA-approved SARS-CoV-2 vaccines currently provide excellent protection against severe disease. Despite this, immunity can wane relatively fast, particularly in the elderly and novel viral variants capable of evading infection- and
Externí odkaz:
https://doaj.org/article/e0f2e171cb6d49a6bff9be7e335d5f23
Autor:
Stephanie Tang, Ana Cassandra De Jesus, Deebly Chavez, Sayahi Suthakaran, Sarah K.L. Moore, Keshon Suthakaran, Sonya Homami, Raveen Rathnasinghe, Alison J. May, Michael Schotsaert, Clemente J. Britto, Jahar Bhattacharya, Jaime L. Hook
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Secondary lung infection by inhaled Staphylococcus aureus (SA) is a common and lethal event for individuals infected with influenza A virus (IAV). How IAV disrupts host defense to promote SA infection in lung alveoli, where fatal lung injury occurs,
Externí odkaz:
https://doaj.org/article/4566af0911ed4a1eb0dce8064a5f108a
Akademický článek
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Akademický článek
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Autor:
Lauren A. Chang, Angela Choi, Raveen Rathnasinghe, Prajakta Warang, Moataz Noureddine, Sonia Jangra, Yong Chen, Bruno G. De Geest, Michael Schotsaert
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Eosinophils are important mediators of mucosal tissue homeostasis, anti-helminth responses, and allergy. Lung eosinophilia has previously been linked to aberrant Type 2-skewed T cell responses to respiratory viral infection and may also be a conseque
Externí odkaz:
https://doaj.org/article/f7543b749d5d433c9261b41937fc7018
Autor:
Raveen Rathnasinghe, Sonia Jangra, Chengjin Ye, Anastasija Cupic, Gagandeep Singh, Carles Martínez-Romero, Lubbertus C. F. Mulder, Thomas Kehrer, Soner Yildiz, Angela Choi, Stephen T. Yeung, Ignacio Mena, Virginia Gillespie, Jana De Vrieze, Sadaf Aslam, Daniel Stadlbauer, David A. Meekins, Chester D. McDowell, Velmurugan Balaraman, Michael J. Corley, Juergen A. Richt, Bruno G. De Geest, Lisa Miorin, PVI study group, Florian Krammer, Luis Martinez-Sobrido, Viviana Simon, Adolfo García-Sastre, Michael Schotsaert
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Here, Rathnasinghe et al. characterize the pathogenesis of a mouse-adapted SARS-CoV-2 in infected obese and aged mice, and identify mutations that are present in SARS-CoV-2 variants of concern, associated with higher transmissibility.
Externí odkaz:
https://doaj.org/article/12c6e893f2b043239df7246c95215cf6