Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Rathnam Chaguturu"'
Autor:
Kenneth R Peterson, Flávia C Costa, Halyna Fedosyuk, Renee Y Neades, Allen M Chazelle, Lesya Zelenchuk, Andrea H Fonteles, Parmita Dalal, Anuradha Roy, Rathnam Chaguturu, Biaoru Li, Betty S Pace
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107006 (2014)
Decades of research have established that the most effective treatment for sickle cell disease (SCD) is increased fetal hemoglobin (HbF). Identification of a drug specific for inducing γ-globin expression in pediatric and adult patients, with minima
Externí odkaz:
https://doaj.org/article/79455023deb64500abcc77b70ee29150
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e44686 (2012)
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that induces a battery of cytoprotective genes involved in antioxidant defense through binding to Antioxidant Response Elements (ARE) located in the promoter regions of thes
Externí odkaz:
https://doaj.org/article/861bf9ee9cdf4ed4be4b8961a4a08638
Autor:
Rathnam Chaguturu
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e392e54cbcc39195f98cbc81ae7b1ba6
https://doi.org/10.2174/1386207326666230430004132
https://doi.org/10.2174/1386207326666230430004132
Autor:
Rathnam Chaguturu
Publikováno v:
Combinatorial chemistryhigh throughput screening. 25(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46479045d0db5f1e14ab1382e2e5f360
https://pubmed.ncbi.nlm.nih.gov/35139787
https://pubmed.ncbi.nlm.nih.gov/35139787
Publikováno v:
Natural product communications. 14(1)
We report relative bioactivities of extracts prepared from a large collection of plants from three national parks in Panama. Over 181 plants were collected, taxonomically identified and their detannified dichloromethane (DCM)-methanolic extracts were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce09c7c7de410414443b0d2bab93a2be
https://pubmed.ncbi.nlm.nih.gov/31938081
https://pubmed.ncbi.nlm.nih.gov/31938081
Autor:
Rathnam Chaguturu, Michelle Palmer
Publikováno v:
Expert Opinion on Drug Discovery. 12:537-540
The pharmaceutical industry continues to be challenged by skyrocketing costs and plummeting productivity in R&D, while many key products are facing patent expiration. Early discovery research from ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20350ef1ad6cd5372463ce48f7189ab2
https://doi.org/10.1080/17460441.2017.1318124
https://doi.org/10.1080/17460441.2017.1318124
Autor:
Bhushan Patwardhan, Rathnam Chaguturu
Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic T
Autor:
Rathnam Chaguturu, Bhushan Patwardhan
To address many challenges faced in successfully bringing a medicine to market, all the stakeholders of the biomedical ecosystem need to collaborate. This ecosystem includes academia, nonprofit and for-profit research institutions, government agencie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645a68c89343613ae44b9e5554ab2f6e
https://doi.org/10.1016/b978-0-12-801814-9.00015-5
https://doi.org/10.1016/b978-0-12-801814-9.00015-5
Chemical informatics is a broad discipline spanning a diverse array of methods ranging from those that have been around for decades all the way to cutting-edge techniques that are still emerging as I write these words. Given this book’s focus on in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f131e19f383ca76f52188e91cbc3b7e3
https://doi.org/10.1016/b978-0-12-801814-9.00010-6
https://doi.org/10.1016/b978-0-12-801814-9.00010-6