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Akademický článek

Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer.

Autor: Sekhar KR; Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, 2220 Pierce Avenue, 597 Preston Research Building, Nashville, TN, 37232, USA., Hanna DN; Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, 2220 Pierce Avenue, 597 Preston Research Building, Nashville, TN, 37232, USA., Cyr S; Vanderbilt University School of Medicine, Nashville, TN, USA., Baechle JJ; Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, 2220 Pierce Avenue, 597 Preston Research Building, Nashville, TN, 37232, USA., Kuravi S; Division of Hematologic Malignancies and Cellular Therapeutics, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA., Balusu R; Division of Hematologic Malignancies and Cellular Therapeutics, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA., Rathmell K; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Baregamian N; Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, 2220 Pierce Avenue, 597 Preston Research Building, Nashville, TN, 37232, USA. naira.baregamian@vumc.org.

Publikováno v: Scientific reports [Sci Rep] 2022 Nov 12; Vol. 12 (1), pp. 19396. Date of Electronic Publication: 2022 Nov 12.

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Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma

Autor: Serody, J.S., Smith, C.C., Kim, W.Y., Bixby, L.M., Bortone, D.S., Swanstrom, R., Beckermann, K.E., Bhanot, G., Vincent, B.G., Selitsky, S.R., Lee, S.J., Parker, J.S., Milowsky, M.I., Ganesan, S., Cubas, A.A., Wallen, E.M., Rathmell, K., Panda, A.

Human endogenous retroviruses (hERVs) are remnants of exogenous retroviruses that have integrated into the genome throughout evolution. We developed a computational workflow, hervQuant, which identified more than 3,000 transcriptionally active hERVs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6ce8e4834f499df4a0e6b274166c144

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Akademický článek

A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction.

Autor: Schneider, Carolin¹, Hilbert, Jorina¹, Genevaux, Franziska², Höfer, Stefanie³, Krauß, Lukas¹, Schicktanz, Felix⁴, Contreras, Constanza Tapia¹, Jansari, Shaishavi⁵, Papargyriou, Aristeidis^2,6,7,8, Richter, Thorsten¹, Alfayomy, Abdallah M.^9,10, Falcomatà, Chiara^11,12, Schneeweis, Christian¹¹, Orben, Felix², Öllinger, Ruppert¹³, Wegwitz, Florian⁵, Boshnakovska, Angela¹⁴, Rehling, Peter^14,15, Müller, Denise¹⁶, Ströbel, Philipp^16,17,18

Publikováno v: Advanced Science. 8/21/2024, Vol. 11 Issue 31, p1-18. 18p.

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Akademický článek

Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway.

Autor: Wei, Wanhui^1,2,3,4 (AUTHOR), Lu, Yuanyuan⁵ (AUTHOR), Hu, Qian⁶ (AUTHOR), Yin, Jinwen^1,2 (AUTHOR), Wang, Youwei^1,2 (AUTHOR), Zhang, Heng^3,4 (AUTHOR) 653262549@qq.com, Zhao, Qiu^1,2 (AUTHOR) qiuzhao@whu.edu.cn, Liu, Lan^1,2 (AUTHOR) lliugi@whu.edu.cn

Publikováno v: Cellular Oncology (2211-3428). Feb2024, Vol. 47 Issue 1, p321-341. 21p.

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Akademický článek

Inflammation-Associated Cytotoxic Agents in Tumorigenesis.

Autor: Arnhold, Jürgen¹ (AUTHOR) juergen.arnhold@medizin.uni-leipzig.de

Publikováno v: Cancers. Jan2024, Vol. 16 Issue 1, p81. 35p.

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Akademický článek

Identification of pyroptosis-related subtypes and comprehensive analysis of characteristics of the tumor microenvironment infiltration in clear cell renal cell carcinoma.

Autor: Zeng, Jiayi¹ (AUTHOR), Zhu, Ping² (AUTHOR), Tang, Yanlin³ (AUTHOR), Zhang, Changzheng³ (AUTHOR), Ye, Chujin³ (AUTHOR), Cheng, Shouyu³ (AUTHOR), Tian, Kaiwen³ (AUTHOR), Yang, Bowen³ (AUTHOR), Zeng, Weinan³ (AUTHOR), Liu, Yanjun² (AUTHOR) yanjun@smu.edu.cn, Xian, Zhiyong^1,3 (AUTHOR) urologist@163.com, Yu, Yuming^3,4 (AUTHOR) yuym72@163.com

Publikováno v: Scientific Reports. 11/20/2023, Vol. 13 Issue 1, p1-19. 19p.

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Akademický článek

Vitamin C in the Management of Thyroid Cancer: A Highway to New Treatment?

Autor: Gorini, Francesca, Tonacci, Alessandro

Publikováno v: Antioxidants; Oct2024, Vol. 13 Issue 10, p1242, 42p

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Akademický článek

A Phase II Clinical Trial of Pembrolizumab Efficacy and Safety in Advanced Renal Medullary Carcinoma.

Autor: Nze, Chijioke¹ (AUTHOR) ccnze@mdanderson.org, Msaouel, Pavlos^2,3,4 (AUTHOR) pmsaouel@mdanderson.org, Derbala, Mohamed H.⁵ (AUTHOR) mhderbala@mdanderson.org, Stephen, Bettzy⁵ (AUTHOR) bastephen@mdanderson.org, Abonofal, Abdulrahman⁶ (AUTHOR) rhnofal@gmail.com, Meric-Bernstam, Funda⁵ (AUTHOR) fmeric@mdanderson.org, Tannir, Nizar M.² (AUTHOR) ntannir@mdanderson.org, Naing, Aung⁵ (AUTHOR) ntannir@mdanderson.org

Publikováno v: Cancers. Aug2023, Vol. 15 Issue 15, p3806. 11p.

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