Amelioration of C-Reactive Protein and Lectin Like Oxidized Low Density Lipoprotein Receptor Complex Induced Endothelial Dysfunction by Oligomeric Proanthocyanidins

Autor: Sankar Jamuna, Rathinavel Ashokkumar, Sivasitambaram Niranjali Devaraj

Publikováno v: Applied biochemistry and biotechnology.

C-reactive protein (CRP) is a well-established biochemical marker for atherosclerosis. Modification of LDL inside the artery wall favors the elevation of this acute phase protein. Hence, this mechanism is considered an important factor to trigger the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe4e52fb73a817c48ace3463b72c1fc
https://pubmed.ncbi.nlm.nih.gov/35357665

Oligomeric proanthocyanidins and epigallocatechin gallate aggravate autophagy of foam cells through the activation of Class III PI3K/Beclin1‐complex mediated cholesterol efflux

Autor: Sankar Jamuna, Rathinavel Ashokkumar, Sivasithaparam Niranjali Devaraj, Mohammed Sadullah Sakeena Sadullah

Publikováno v: BioFactors. 45:763-773

Foam cells are specialized types of cells which predominate the necrotic core of atherosclerotic plaque. Recently, autophagy-mediated cholesterol efflux from foam cells has been proposed as a beneficial therapy for atherosclerosis. The purpose of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbc06d89f8914b8b2c8818836422af8
https://doi.org/10.1002/biof.1537

Vitexin protects isoproterenol induced post myocardial injury by modulating hipposignaling and ER stress responses

Autor: Rathinavel Ashokkumar, Sankar Jamuna, S. Niranjali Devaraj, Sakeena Sadullah

Publikováno v: Biochemical and biophysical research communications. 496(2)

The molecular mechanisms involved in ER stress-induced post myocardial injury remain elusive. In this study, we have investigated the molecular mechanism of ER stress-mediated myocyte death in Isoproterenol (ISO) induced myocardial infarction and its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21dcd096b82936b6b9a825a828831ef2
https://pubmed.ncbi.nlm.nih.gov/29406244

Potential antioxidant and cytoprotective effects of essential oil extracted from Cymbopogan citratus on OxLDL and H2O2 LDL induced Human Peripheral Blood Mononuclear Cells (PBMC)

Autor: Sakeena Sadullah, Gokul Shanmuganathan, Senguttuvan Sivan Mozhi, S. Niranjali Devaraj, Sankar Jamuna, Rathinavel Ashokkumar

Publikováno v: Food Science and Human Wellness, Vol 6, Iss 2, Pp 60-69 (2017)
Food science and human wellness, 6(2):60-69

Cymbopogon citratus (lemon grass) is commonly used in traditional folk medicine. The essential oil extracted from C. citratus has been reported as a potential anti-oxidant and anti-inflammatory agent. This study has been designed to explore the prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df73cf6bbb44f3361be48519fbc8ba4

Oligomeric proanthocyanidins mitigate cholesterol and cholic acid diet-induced hepatic dysfunction in male Sprague Dawley rats.

Autor: Sankar J; Department of Biochemistry, University of Madras, Guindy campus, Chennai, Tamil Nadu, India., Rathinavel A; Department of Biochemistry, University of Madras, Guindy campus, Chennai, Tamil Nadu, India., Mohammed Sadullah SS; Department of Biochemistry, University of Madras, Guindy campus, Chennai, Tamil Nadu, India., Devaraj SN; Department of Biochemistry, University of Madras, Guindy campus, Chennai, Tamil Nadu, India.

Publikováno v: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2018 Oct 01, pp. e22234. Date of Electronic Publication: 2018 Oct 01.