Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ratheishan Rajesan"'
Autor:
Mingdong Yang, Bo Lönnerdal, Haibo Xu, Jo Watson-MacDonell, Ratheishan Rajesan, Shinya Ito, Satoko Uematsu, Janine R. Hutson, Patricia A. Harper, Richard B. Kim
Publikováno v:
British Journal of Pharmacology. 146:296-305
During the treatment of neonatal apnea, formula-fed infants, compared to breastfed infants, show nearly three-fold increase in clearance of caffeine, a substrate of cytochrome P450 1A (CYP1A) and in part CYP3A4. However, human milk is known to contai
Autor:
Ikumi Tamai, Haibo Xu, Shinya Ito, Patricia A. Harper, Lillian Chan, Bruce Kwok, Wen Gao, Ariko Yamauchi, Shinichiro Takahashi, Akira Tsuji, Jun-ichi Nezu, Upinder Dhillon, Bernice Wang, Ratheishan Rajesan, John W. Semple
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 290(3)
The barrier function of the human mammary gland collapses if challenged with cationic drugs, causing their accumulation in milk. However, underlying molecular mechanisms are not well understood. To gain insight into the mechanism, we characterized tr