Výsledky vyhledávání - "Rastko, Golouh"

Follow–up of females with atypical glandular cells on Pap smears

Autor: Ana Planinc, Alenka Repše Fokter, Rastko Golouh

Publikováno v: Acta Medico-Biotechnica. 5:33-39

Purpose: Atypical glandular cells (AGC) are often associated with clinically significant lesions, but the interpretation of AGC and the associated lesions on Pap smears remains challenging, even for experienced cytopathologists. The frequency and his

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93d1e414379cef34e8ed3a101bbf5871
https://doi.org/10.18690/actabiomed.73

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Akademický článek

Hydrolysis Profiles of Formalin Fixed Paraffin-Embedded Tumors Based on IOD (Integrated Optical Density) and Nuclear Texture Feature Measurements

Autor: Margareta Fležar, Marija Us‐Krašovec, Mario žganec, Jaka Lavrenčak, Rastko Golouh

Publikováno v: Analytical Cellular Pathology, Vol 19, Iss 3-4, Pp 111-118 (1999)

The aim of the study was to determine optimal hydrolysis time for the Feulgen DNA staining of archival formalin fixed paraffin‐embedded surgical samples, prepared as single cell suspensions for image cytometric measurements. The nuclear texture fea

Externí odkaz: https://doaj.org/article/2ca9e3693abd4662863556214e886278

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Chemoendocrine Compared With Endocrine Adjuvant Therapies for Node-Negative Breast Cancer: Predictive Value of Centrally Reviewed Expression of Estrogen and Progesterone Receptors—International Breast Cancer Study Group

Autor: Robert W. Brown, Alan S. Coates, Aron Goldhirsch, Richard D. Gelber, Karen N. Price, Piergiovanni Grigolato, Monica Castiglione-Gertsch, Eugenio Maiorano, Barry A. Gusterson, Komala Pillay, Mauro G. Mastropasqua, Stephen G. Braye, Rastko Golouh, Christian Öhlschlegel, Meredith M. Regan, Tiziana Perin, Tiziana Rusca, Anikó Kovács, Giuseppe Viale

Publikováno v: Journal of Clinical Oncology. 26:1404-1410

Purpose To centrally assess estrogen receptor (ER) and progesterone receptor (PgR) levels by immunohistochemistry and investigate their predictive value for benefit of chemo-endocrine compared with endocrine adjuvant therapy alone in two randomized c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bf2278c84aa483356d9ac7b7ccc03e
https://doi.org/10.1200/jco.2007.10.6393

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The prognostic value of Stathmin-1, S100A2, and SYK proteins in ER-positive primary breast cancer patients treated with adjuvant tamoxifen monotherapy: an immunohistochemical study

Autor: Mieke Timmermans, John W.M. Martens, John A. Foekens, Ralf Lesche, Rastko Golouh, Pernille Autzen Usher, Nils Brünner, Sabine Maier, Manfred Schmitt, Tanja Cufer, Aleksander Sadikov, Petra Nussdorfer

Publikováno v: Breast Cancer Research and Treatment, 110(2), 317-326. Springer New York

Introduction We recently found that DNA methylation of S100A2, spleen tyrosine kinase (SYK), and Stathmin-1 (STMN1) correlates with response to tamoxifen therapy in metastatic breast cancer. In this retrospective study, we investigated immunohistoche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60413418786d27e1f416bd6c65513e1a
https://hdl.handle.net/1765/29298

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Multicenter validation of a gene expression-based prognostic signature in lymph node-negative primary breast cancer

Publikováno v: Journal of Clinical Oncology, 24(11), 1665-1671. American Society of Clinical Oncology
Journal of Clinical Oncology, 24, 11, pp. 1665-71
Journal of Clinical Oncology, 24, 1665-71

Purpose We previously identified in a single-center study a 76-gene prognostic signature for lymph node-negative (LNN) breast cancer patients. The aim of this study was to validate this gene signature in an independent more diverse population of LNN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d1086f94ca61e1df74cf20c8f28312
https://doi.org/10.1200/JCO.2005.03.9115

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Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues

Autor: Tomaz Langerholc, Rastko Golouh, Vito Turk, Bernd Werle, Boris Turk, Matjaz Jeras, Urska Repnik, Valentina Zavasnik Bergant, Aleš Premzl, Janko Kos, Andreja Sekirnik

Publikováno v: Experimental Cell Research. 306:103-113

Cathepsin X, a recently discovered lysosomal cysteine protease, shares common structural features and activity properties with cysteine protease cathepsin B. Based on its widespread mRNA distribution in primary tumors and tumor cell lines, a redundan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5d79a0f7d943b988917047e904c50e
https://doi.org/10.1016/j.yexcr.2004.12.006

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Decreased immunoreactivity for p27 protein in patients with early-stage breast carcinoma is correlated with HER-2/neuoverexpression and with benefit from one course of perioperative chemotherapy in patients with negative lymph node status

Publikováno v: Cancer. 97:1591-1600

BACKGROUND The objective of this study was to clarify the prognostic and predictive value of immunoreactivity for the cyclin-dependent kinase inhibitor p27(Kip1) in patients with early-stage breast carcinoma and to investigate its relation with clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0113dcffe10a745b64f8b9efd143d674
https://doi.org/10.1002/cncr.11224

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Ki-67 expression in breast carcinoma

Autor: John P. Collins, Susan Murray, Rastko Golouh, Alan S. Coates, Richard D. Gelber, Monica Castiglione-Gertsch, Karen N. Price, Barry A. Gusterson, Helen Trihia, Aron Goldhirsch

Publikováno v: Cancer. 97:1321-1331

BACKGROUND The number of mitoses and, thus, the proliferative capacity of a tumor is one of the most crucial variables for tumor grading. The Ki-67 nuclear antigen may be considered as an alternative to mitotic counts in grading schemes and as a sing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e214d2ef0acc91042082f1e219d8d770
https://doi.org/10.1002/cncr.11188

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Toker cells are probably precursors of Paget cell carcinoma: a morphological and ultrastructural description

Autor: Vincenzo Eusebi, Johannes L. Peterse, Maria Pia Foschini, Christine M. Betts, Rastko Golouh, Gianluca Marucci

Publikováno v: Virchows Archiv. 441:117-123

The present paper documents an investigation of the morphology, immunohistochemistry, and ultrastructure of Toker cells (TC), aiming for a better definition of these elements and better understanding of their histogenesis. We studied 12 nipples remov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5601a4b8133f05562f03cfa841282d
https://doi.org/10.1007/s00428-001-0581-x

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Causes of microsatellite instability in colorectal tumors

Autor: Uroš Potočnik, Damjan Glavač, Rastko Golouh, Metka Ravnik-Glavač

Publikováno v: Cancer Genetics and Cytogenetics. 126:85-96

Microsatellite instability (MSI) analysis was performed using a "reference panel" of microsatellite markers in 345 unselected primary colorectal cancers (CRC). Thirty-five (10%) tumors were classified as high MSI (MSI-H). We identified 6 (17%) MSI-H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::854b8f49b05d73cfd5eaad860ee46c49
https://doi.org/10.1016/s0165-4608(00)00399-x

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