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pro vyhledávání: '"Rastija, Ana"'
Autor:
Dominko, Kristina, Rastija, Ana, Smiljanic, Kosara, Mladenovic, Aleksandra, Lešnjaković, Lucija, Kanazir, Selma, Milanovic, Desanka, Hecimovic, Silva
Publikováno v:
In Mechanisms of Ageing and Development October 2022 207
Autor:
Rastija, Ana
Bolest Niemann-Pick tipa C (NPC) je rijetka nasljedna neurodegenerativna bolest nakupljanja slobodnog kolesterola i drugih lipida uzrokovana mutacijama u genu NPC1 ili NPC2, koja pokazuje niz patoloških sličnosti s kompleksnom Alzheimerovom bolesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4aeba96e281346e365bfe53178f17c0a
Niemann-Pick type C disease (NPC) is a rare inherited lysosomal storage disorder characterized by cholesterol accumulation leading to progressive neurodegeneration and neuroinflammation. It is intriguing that this rare monogenic disease (caused by mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::fdfb1f68d6913f9e0d33ce0552fac4ea
https://www.bib.irb.hr/1212724
https://www.bib.irb.hr/1212724
Akademický článek
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Autor:
Hecimovic, Silva, Dominko, Kristina, Rastija, Ana, Meglaj, Sarah, Vidatić, Lea, Babić, Andrea, Colombo, Alessio, Tahirovic, Sabina
It is intriguing that Niemann-Pick type C disease (NPC) shares several features with Alzheimer’s disease (AD), including enhanced levels of amyloid-β peptides (Aβ) due to enhanced β-amyloid precursor protein (APP) cleavage by BACE1, a key enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::84f5e194fb13bf1c127283e3f9829254
https://www.bib.irb.hr/1176213
https://www.bib.irb.hr/1176213
Niemann-Pick type C disease (NPC) is a rare, fatal lipid storage disorder characterized primarily by progressive neruodegeneration of Purkinje neurons in the cerebellum and neuroinflammation (activation of microglia and astrocytes). NPC is caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::dc6a0af48ed7c0f4d85cab0c2e4922a3
https://www.bib.irb.hr/1175493
https://www.bib.irb.hr/1175493
Niemann-Pick type C (NPC) is a rare inherited lysosomal storage disorder that shares several pathological features with Alzheimer's disease (AD), including dysfunction of the endolysosomal pathway and increased levels of amyloid-beta peptides (Aβ).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::5f1b957ff67cea60a195e76a0821ce6c
https://www.bib.irb.hr/1172908
https://www.bib.irb.hr/1172908
The β-site amyloid precursor protein cleavage enzyme 1 (BACE1), has been considered as a therapeutic target for the treatment of Alzheimer’s disease (AD) as it initiates the proteolytic cleavage of the β-amyloid precursor protein (APP) to generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::12aad08f31d00692d4f493f0571f9c35
https://www.bib.irb.hr/1175482
https://www.bib.irb.hr/1175482
Niemann-Pick type C disease (NPC) is a rare, recessive, fatal, lipid storage disorder caused by mutations in NPC1 or NPC2 genes. NPC1/NPC2 code for cholesterol transport proteins. Their dysfunction leads to accumulation of free cholesterol and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::dea7dd3728879d39fc3c5f68b9fcaded
https://www.bib.irb.hr/1175484
https://www.bib.irb.hr/1175484
Autor:
Rastija, Ana
Poznavanje mehanizama odgovornih za diferencijaciju tkiva i razvoj organizma veliki je izazov razvojne biologije, ali i molekularne onkologije. Koordinirano ponašanje i kretanje stanica nužni su za morfogenezu, zacijeljivanje rana i tumorigenezu. K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d40a277d1d18d1229ded5387ab589037
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:3255/datastream/PDF
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:3255/datastream/PDF