Effect of the CCR5 antagonist maraviroc on the occurrence of immune reconstitution inflammatory syndrome in HIV (CADIRIS): a double-blind, randomised, placebo-controlled trial

Autor: Sierra-Madero, Juan G, Ellenberg, Susan S, Rassool, Mohammed S, Tierney, Ann, Belaunzarán-Zamudio, Pablo F, López-Martínez, Alondra, Piñeirúa-Menéndez, Alicia, Montaner, Luis J, Azzoni, Livio, Benítez, César Rivera, Sereti, Irini, Andrade-Villanueva, Jaime, Mosqueda- Gómez, Juan L, Rodriguez, Benigno, Sanne, Ian, Lederman, Michael M

Publikováno v: In The Lancet HIV November 2014 1(2):e60-e67

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Chemokine Receptor 5 (CCR5) Antagonist to Decrease the Occurrence of Immune Reconstitution Inflammatory Syndrome in HIV-Infection: The CADIRIS Study

Autor: Sierra-Madero, Juan G., Ellenberg, Susan, Rassool, Mohammed S., Tierney, Ann, Belaunzarán-Zamudio, Pablo F., López-Martínez, Alondra, Piñeirúa-Menéndez, Alicia, Montaner, Luis J., Azzoni, Livio, Benítez, César Rivera, Sereti, Irini, Andrade-Villanueva, Jaime, Mosqueda-Gómez, Juan L., Rodriguez, Benigno, Sanne, Ian, Lederman, Michael M.

Immune Reconstitution Inflammatory Syndrome (IRIS) is a common complication of antiretroviral therapy (ART) in HIV-infected patients. IRIS is associated with an increased risk of hospitalization and death. We ascertained whether CCR5 blockade using m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ac582da1ecc54dc8d9680644df1e51c
https://europepmc.org/articles/PMC4563882/

Antiretroviral therapy in HIV‐1‐infected individuals with CD4 count below 100 cells/mm3results in differential recovery of monocyte activation

Autor: Patro, Sean C., Azzoni, Livio, Joseph, Jocelin, Fair, Matthew G., Sierra‐Madero, Juan G., Rassool, Mohammed S., Sanne, Ian, Montaner, Luis J.

Publikováno v: Journal of Leukocyte Biology; July 2016, Vol. 100 Issue: 1 p223-231, 9p

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Chemokine Receptor 5 (CCR5) Antagonist to Decrease the Occurrence of Immune Reconstitution Inflammatory Syndrome in HIV-Infection: The CADIRIS Study.

Autor: Sierra-Madero JG; Departmento de Infectología, Instituto Nacional de Ciencias Médicas y Nutrición 'Salvador Zubirán'. Vasco de Quiroga 15, Col. Sección XVI, Del. Tlalpan. México DF, México. CP 14000., Ellenberg S; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine. 611 Blockley Hall. 423 Guardian Drive, Philadelphia, PA 19104-602. USA., Rassool MS; Clinical HIV Research Unit, Department of Internal Medicine, Faculty of Health Sciences, University of Witwatersrand. Perth Ave, Westdene. Johannesburg, South Africa., Tierney A; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine. 611 Blockley Hall. 423 Guardian Drive, Philadelphia, PA 19104-602. USA., Belaunzarán-Zamudio PF; Departmento de Infectología, Instituto Nacional de Ciencias Médicas y Nutrición 'Salvador Zubirán'. Vasco de Quiroga 15, Col. Sección XVI, Del. Tlalpan. México DF, México. CP 14000., López-Martínez A; Departmento de Infectología, Instituto Nacional de Ciencias Médicas y Nutrición 'Salvador Zubirán'. Vasco de Quiroga 15, Col. Sección XVI, Del. Tlalpan. México DF, México. CP 14000., Piñeirúa-Menéndez A; Departmento de Infectología, Instituto Nacional de Ciencias Médicas y Nutrición 'Salvador Zubirán'. Vasco de Quiroga 15, Col. Sección XVI, Del. Tlalpan. México DF, México. CP 14000., Montaner LJ; HIV-1 Immunopathogenesis Laboratory, The Wistar Institute. 3601 Spruce Street, Philadelphia, PA 19104. USA., Azzoni L; HIV-1 Immunopathogenesis Laboratory, The Wistar Institute. 3601 Spruce Street, Philadelphia, PA 19104. USA., Benítez CR; Servicio de Infectología, Hospital General de México, Dr. Balmis 148, Col. Doctores. México DF, México. CP 06726., Sereti I; HIV Pathogenesis Unit, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases/National Institutes of Health. 10 Center Drive, Building 10, 11C-103. Bethesda, MD 20892., Andrade-Villanueva J; Unidad de VIH, Hospital Civil de Guadalajara. Calle Hospital 278 S.H. Col. Alcalde Barranquitas. Guadalajara, Jalisco, México. CP 44280., Mosqueda-Gómez JL; Centro de Ambulatorio de Prevención y Atención en SIDA e Infecciones de Transmisión Sexual León. Calle 20 de enero # 927, Col. Obregón. León, Guanajuato, México CP 37000., Rodriguez B; Center for AIDS Research, Case Western Reserve University. 2061 Cornell Rd, Cleveland OH 44106. USA., Sanne I; Clinical HIV Research Unit, Department of Internal Medicine, Faculty of Health Sciences, University of Witwatersrand. Perth Ave, Westdene. Johannesburg, South Africa ; Center for International Development, Boston University. USA., Lederman MM; Center for AIDS Research, Case Western Reserve University. 2061 Cornell Rd, Cleveland OH 44106. USA.

Publikováno v: The lancet. HIV [Lancet HIV] 2014 Nov 01; Vol. 1 (2), pp. e60-e67.