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Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants.

Autor: Miousse IR; Department of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. Electronic address: IRacinemiousse@uams.edu., Murphy LA; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, Midland, MI, USA. Electronic address: Murphy3@dow.com., Lin H; Department of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. Electronic address: HLin@uams.edu., Schisler MR; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, Midland, MI, USA. Electronic address: MRSchisler@dow.com., Sun J; Division of Systems Biology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address: Jinchun.Sun@fda.hhs.gov., Chalbot MG; Department of Environmental Health Sciences, Ryals School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35246, USA. Electronic address: chalbot@uab.edu., Sura R; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, Midland, MI, USA. Electronic address: radhakrishna.sura@abbvie.com., Johnson K; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, Midland, MI, USA. Electronic address: kjjohnson2@dow.com., LeBaron MJ; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, Midland, MI, USA. Electronic address: mjlebaron@dow.com., Kavouras IG; Department of Environmental Health Sciences, Ryals School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35246, USA. Electronic address: kavouras@uab.edu., Schnackenberg LK; Division of Systems Biology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address: Laura.Schnackenberg@fda.hhs.gov., Beger RD; Division of Systems Biology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address: Richard.Beger@fda.hhs.gov., Rasoulpour RJ; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, Midland, MI, USA. Electronic address: RRasoulpour@dow.com., Koturbash I; Department of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. Electronic address: IKoturbash@uams.edu.

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2017 Nov; Vol. 109 (Pt 1), pp. 690-702. Date of Electronic Publication: 2017 May 08.

Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop.

Autor: Aigner A; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Clinical Pharmacology, Leipzig University, 04107 Leipzig, Germany., Buesen R; BASF SE, 67056 Ludwigshafen, Germany., Gant T; Centre for Radiation, Chemical and Environmental Hazards, Public Health England (PHE), Harwell Campus, Chilton, Oxfordshire, OX11 0RQ, UK., Gooderham N; Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London SW7 2AZ, UK., Greim H; Technical University Munich, 85354 Freising-Weihenstephan, Germany., Hackermüller J; Young Investigators Group Bioinformatics and Transcriptomics, Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ, 04318 Leipzig, Germany., Hubesch B; European Chemicals Council (Cefic) Long-Range Research Initiative, 1160 Brussels, Belgium; Hubesch Consult BVBA, 1600 Sint-Pieters-Leeuw, Belgium., Laffont M; European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC), 1160 Brussels, Belgium., Marczylo E; Centre for Radiation, Chemical and Environmental Hazards, Public Health England (PHE), Harwell Campus, Chilton, Oxfordshire, OX11 0RQ, UK., Meister G; Biochemistry Centre Regensburg, University of Regensburg, 93053 Regensburg, Germany., Petrick JS; Monsanto Company, St. Louis, MO 63167, USA., Rasoulpour RJ; Dow AgroSciences, Indianapolis, IN 46268, USA., Sauer UG; Scientific Consultancy - Animal Welfare, 85579 Neubiberg, Germany., Schmidt K; BioMath GmbH, 18055 Rostock, Germany., Seitz H; Institut de Génétique Humain (IGH), Centre National de la Recherche Scientifique - National Centre of Scientific Research (CNRS), 34396 Montpellier Cedex 5, France., Slack F; Department of Pathology, Institute for RNA Medicine, Beth Israel Deaconess Medical Center - BIDMC Cancer Center Harvard Medical School, Boston, MA 02215, USA., Sukata T; Sumitomo Chemical Europe, 1830 Machelen, Belgium., van der Vies SM; Neuroscience Amsterdam, VU University Medical Centre, 1081HV 1117, Amsterdam, The Netherlands., Verhaert J; Monsanto Company, 1150 Brussels, Belgium., Witwer KW; The John Hopkins University School of Medicine, Baltimore, MD 21205, USA., Poole A; European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC), 1160 Brussels, Belgium. Electronic address: alan.poole@ecetoc.org.

Publikováno v: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2016 Dec; Vol. 82, pp. 127-139. Date of Electronic Publication: 2016 Sep 20.

A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study.

Autor: Paul Friedman K; a Human Safety, Bayer CropScience LP, Research Triangle Park , NC , USA ;, Papineni S; b Human Health Assessment, Dow AgroSciences LLC , Indianapolis , IN , USA ;, Marty MS; c Toxicology & Environmental Research and Consulting, The Dow Chemical Company , Midland , MI , USA ;, Yi KD; d Toxicology and Health Sciences, Syngenta Crop Protection LLC , Greensboro , NC , USA., Goetz AK; d Toxicology and Health Sciences, Syngenta Crop Protection LLC , Greensboro , NC , USA., Rasoulpour RJ; b Human Health Assessment, Dow AgroSciences LLC , Indianapolis , IN , USA ;, Kwiatkowski P; a Human Safety, Bayer CropScience LP, Research Triangle Park , NC , USA ;, Wolf DC; d Toxicology and Health Sciences, Syngenta Crop Protection LLC , Greensboro , NC , USA., Blacker AM; a Human Safety, Bayer CropScience LP, Research Triangle Park , NC , USA ;, Peffer RC; d Toxicology and Health Sciences, Syngenta Crop Protection LLC , Greensboro , NC , USA.

Publikováno v: Critical reviews in toxicology [Crit Rev Toxicol] 2016 Oct; Vol. 46 (9), pp. 785-833. Date of Electronic Publication: 2016 Jun 27.