Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rasoul Pourebrahimabadi"'
p53 Mediated Bone Marrow Mesenchymal Stem Cell Expansion Supports Acute Myeloid Leukemia Development
Autor:
Carlos E. Bueso-Ramos, Peter P. Ruvolo, Steven M. Kornblau, Rasoul Pourebrahimabadi, Joseph D. Khoury, Lauren B Ostermann, Hung Alex Luong, Rafael Heinz Montoya, Zoe Alaniz, Michael Andreeff
Publikováno v:
Blood. 134:523-523
Acute myeloid leukemia (AML) is a heterogeneous disease that develops within a complex microenvironment. Reciprocal interactions between the bone marrow mesenchymal stem/stromal cells (BM-MSCs) and AML cells can promote AML progression and resistance
Publikováno v:
Cancer Research. 77:3030-3030
TP53 is the most frequently mutated gene in cancer and missense mutations in particular account for the majority of mutations. Mutant p53 proteins exert oncogenic Gain-of-Function (GOF) properties that contribute to increased migration and invasion i
Autor:
Tamara J. Laskowski, Ana M. Crane, Michael C. Holmes, Rasoul Pourebrahimabadi, Yasmine Van Caeneghem, Bart Vandekerckhove, José C. Segovia, Brian R. Davis, Zita Garate
Publikováno v:
Experimental Hematology. 41:S29