Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rasmus Ottosen"'
Autor:
David Olagnier, Ensieh Farahani, Jacob Thyrsted, Julia Blay-Cadanet, Angela Herengt, Manja Idorn, Alon Hait, Bruno Hernaez, Alice Knudsen, Marie Beck Iversen, Mirjam Schilling, Sofie E. Jørgensen, Michelle Thomsen, Line S. Reinert, Michael Lappe, Huy-Dung Hoang, Victoria H. Gilchrist, Anne Louise Hansen, Rasmus Ottosen, Camilla G. Nielsen, Charlotte Møller, Demi van der Horst, Suraj Peri, Siddharth Balachandran, Jinrong Huang, Martin Jakobsen, Esben B. Svenningsen, Thomas B. Poulsen, Lydia Bartsch, Anne L. Thielke, Yonglun Luo, Tommy Alain, Jan Rehwinkel, Antonio Alcamí, John Hiscott, Trine H. Mogensen, Søren R. Paludan, Christian K. Holm
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Viral infections usually cause disease through direct cytopathogenic effects and excessive inflammatory responses. Here, Olagnier et al. show that two NRF2 agonists, 4-OI and DMF, possess broad IFN-independent antiviral activity and decrease host inf
Externí odkaz:
https://doaj.org/article/7eb1ed3741cc4fbfa366937b0037cc35
Autor:
David Olagnier, Ensieh Farahani, Jacob Thyrsted, Julia Blay-Cadanet, Angela Herengt, Manja Idorn, Alon Hait, Bruno Hernaez, Alice Knudsen, Marie Beck Iversen, Mirjam Schilling, Sofie E. Jørgensen, Michelle Thomsen, Line S. Reinert, Michael Lappe, Huy-Dung Hoang, Victoria H. Gilchrist, Anne Louise Hansen, Rasmus Ottosen, Camilla G. Nielsen, Charlotte Møller, Demi van der Horst, Suraj Peri, Siddharth Balachandran, Jinrong Huang, Martin Jakobsen, Esben B. Svenningsen, Thomas B. Poulsen, Lydia Bartsch, Anne L. Thielke, Yonglun Luo, Tommy Alain, Jan Rehwinkel, Antonio Alcamí, John Hiscott, Trine H. Mogensen, Søren R. Paludan, Christian K. Holm
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/7a767ab0a50943a0a5a6e85eaa10ccfe
Autor:
Kira Jennet, Rasmus Ottosen, Esben B. Svenningsen, Martin R. Jakobsen, Thomas B. Poulsen, Mette Biltoft, Han Liu, Tobias Kristensen
Publikováno v:
Liu, H, Ottosen, R N, Jennet, K M, Svenningsen, E B, Kristensen, T F, Biltoft, M, Jakobsen, M R & Poulsen, T B 2021, ' Macrodiolide Diversification Reveals Broad Immunosuppressive Activity That Impairs the cGAS-STING Pathway ', Angewandte Chemie International Edition, vol. 60, no. 34, pp. 18734-18741 . https://doi.org/10.1002/anie.202105793
The development of new immunomodulatory agents can impact various areas of medicine. In particular, compounds with the ability to modulate innate immunological pathways hold significant unexplored potential. Here, we report a modular synthetic approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3ca8f41f306be39d52b8b22123c2ca
https://doi.org/10.1002/anie.202105793
https://doi.org/10.1002/anie.202105793
Autor:
Esben Svenningsen, Rasmus Ottosen, Katrine Jørgensen, Marija Nisavic, Camilla Larsen, Bente Hansen, Yong Wang, Kresten Lindorff-Larsen, Thomas Tørring, Stephan Hacker, Johan Palmfeldt, Thomas Poulsen
Covalently acting compounds experience a strong interest within chemical biology both as molecular probes in studies of fundamental biological mechanisms and/or as novel drug candidates. In this context, the identification of new classes of reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c57c62c18dec174fb011f99e98b4614
https://doi.org/10.26434/chemrxiv-2022-knt5m
https://doi.org/10.26434/chemrxiv-2022-knt5m
Autor:
Christian K. Holm, Anne L. Thielke, Rasmus Ottosen, Thomas B. Poulsen, Jinrong Huang, Alice Knudsen, Lydia Bartsch, Siddharth Balachandran, Marie B. Iversen, Camilla G. Nielsen, Victoria H. Gilchrist, Trine H. Mogensen, Huy-Dung Hoang, Alon Schneider Hait, Sofie E. Jørgensen, Line S. Reinert, Suraj Peri, Jan Rehwinkel, Michael Lappe, Charlotte Möller, Michelle M. Thomsen, John Hiscott, Demi van der Horst, Esben B. Svenningsen, Anne Louise Hansen, Yonglun Luo, Jacob Thyrsted, Manja Idorn, Antonio Alcami, Ensieh Farahani, Julia Blay-Cadanet, Martin R. Jakobsen, Bruno Hernáez, Mirjam Schilling, David Olagnier, Søren R. Paludan, Angela Herengt, Tommy Alain
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Olagnier, D P C, Farahani, E, Jensen, J T, Blay Cadanet, J, Herengt, A A P V, Idorn, M, Schneider Hait, A I, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M M, Reinert, L S, Lappe, M, Hoang, H D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Olagnier, D P C, Farahani, E, Jensen, J T, Blay Cadanet, J, Herengt, A A P V, Idorn, M, Schneider Hait, A I, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M M, Reinert, L S, Lappe, M, Hoang, H D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Versiones preprint disponibles en: http://hdl.handle.net/10261/216920 y http://hdl.handle.net/10261/217161
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 ar
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c770a0f99e983608245ee2ef5c88b25
https://doaj.org/article/7eb1ed3741cc4fbfa366937b0037cc35
https://doaj.org/article/7eb1ed3741cc4fbfa366937b0037cc35
Publikováno v:
Grønkjær, P, Ottosen, R, Joensen, T, Reeve, L, Nielsen, E E & Hedeholm, R 2020, ' Intra-annual variation in feeding of Atlantic cod Gadus morhua : the importance of ephemeral prey bursts ', Journal of Fish Biology, vol. 97, no. 5, pp. 1507-1519 . https://doi.org/10.1111/jfb.14520
Grønkjær, P, Ottosen, R, Joensen, T, Reeve, L, Nielsen, E E & Hedeholm, R 2020, ' Intra-annual variation in feeding of Atlantic cod Gadus morhua : The importance of ephemeral prey bursts ', Journal of Fish Biology, vol. 97, no. 5, pp. 1507-1519 . https://doi.org/10.1111/jfb.14520
Grønkjær, P, Ottosen, R, Joensen, T, Reeve, L, Nielsen, E E & Hedeholm, R 2020, ' Intra-annual variation in feeding of Atlantic cod Gadus morhua : The importance of ephemeral prey bursts ', Journal of Fish Biology, vol. 97, no. 5, pp. 1507-1519 . https://doi.org/10.1111/jfb.14520
Seasonal prey bursts are important for the lifecycles and energy budgets of many predators. Here we document the diet and, especially, the importance of the ephemeral occurrence of capelin as prey for Atlantic cod (Gadus morhua) in Godthaabsfjord, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7beec835a2ec4c16606a0099da759546
https://pure.au.dk/portal/da/publications/intraannual-variation-in-feeding-of-atlantic-cod-gadus-morhua(de26f4e0-a47c-4deb-beac-3d371f05d1aa).html
https://pure.au.dk/portal/da/publications/intraannual-variation-in-feeding-of-atlantic-cod-gadus-morhua(de26f4e0-a47c-4deb-beac-3d371f05d1aa).html
Autor:
Jinrong Huang, Demi van der Horst, Lydia Bartsch, Marie B. Iversen, Line S. Reinert, Camilla Gunderstofte, Esben B. Svenningsen, Anne Louise Hansen, Anne L. Thielke, Tommy Alain, Bruno Hernáez, Huy-Dung Hoang, John Hiscott, Thomas B. Poulsen, Charlotte Möller, Julia Blay Cadanet, Sofie E. Jørgensen, Christian K. Holm, Michael Lappe, Alon Schneider Hait, Jan Rehwinkel, Yonglun Luo, Jacob Thyrsted, Martin R. Jakobsen, Rasmus Ottosen, Michelle M. Thomsen, Søren R. Paludan, Manja Idorn, Antonio Alcami, Suraj Peri, Ensieh Farahani, Angela Herengt, Mirjam Schilling, David Olagnier, Trine H. Mogensen, Alice Knudsen, Siddharth Balachandran, Victoria H. Gilchrist
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here we demonstrate that the NRF2 anti-oxidant gene expression pathway is suppressed in bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78d0c8a4ddfb8c2f90f5fcc79fbd2a4
https://doi.org/10.1101/2020.07.16.206458
https://doi.org/10.1101/2020.07.16.206458
Autor:
Huy-Dung Hoang, Yonglun Luo, Jacob Thyrsted, Esben B. Svenningsen, Anne Louise Hansen, Sofie E. Jørgensen, Jinrong Huang, Camilla G. Nielsen, Rasmus Ottosen, Christian K. Holm, Alice Knudsen, Antonio Alcami, Marie B. Iversen, Lydia Bartsch, Trine H. Mogensen, Martin R. Jakobsen, Anne L. Thielke, Thomas B. Poulsen, Charlotte Möller, Alon Schneider Hait, Jan Rehwinkel, John Hiscott, Michael Lappe, Michelle M. Thomsen, Manja Idorn, Suraj Peri, Line S. Reinert, Ensieh Farahani, Søren R. Paludan, Angela Herengt, Tommy Alain, Siddharth Balachandran, Bruno Hernáez, Demi van der Horst, Victoria H. Gilchrist, Julia Blay-Cadanet, Mirjam Schilling, David Olagnier
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' Author Correction : SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 5419 . https://doi.org/10.1038/s41467-020-19363-y
Nature Communications
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' Author Correction : SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 5419 . https://doi.org/10.1038/s41467-020-19363-y
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here, we demonstrate that the NRF2 antioxidant gene expression pathway is suppressed in bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4188a7a8fff0f36d3b4eac90957497
https://doaj.org/article/7a767ab0a50943a0a5a6e85eaa10ccfe
https://doaj.org/article/7a767ab0a50943a0a5a6e85eaa10ccfe