Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rasmus Kristoffer Pedersen"'
Autor:
Mathias Mølbak Ingholt, Tzu Tung Chen, Franziska Hildebrandt, Rasmus Kristoffer Pedersen, Lone Simonsen
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Plasmodium vivax was endemic in northern Europe until the early twentieth century. Considering climate change and the recent emergence of other vector borne diseases in Europe, historical insight into the relationship between mala
Externí odkaz:
https://doaj.org/article/686cf49ccbfe40eea9c562d5574c98df
Autor:
Johnny T. Ottesen, Vibe Skov, Hans Carl Hasselbalch, Dennis Lund Hansen, Trine Alma Knudsen, Thomas Stauffer Larsen, Morten Andersen, Lasse Kjær, Johanne Gudmand-Hoeyer, Christina Ellervik, Rasmus Kristoffer Pedersen, Marc J. B. Dam, Niels Pallisgaard, Zamra Sajid
Publikováno v:
Cancer Medicine, Vol 9, Iss 6, Pp 2039-2051 (2020)
Cancer Medicine
Pedersen, R K, Andersen, M, Knudsen, T A, Sajid, Z, Gudmand-Hoeyer, J, Dam, M J B, Skov, V, Kjær, L, Ellervik, C, Larsen, T S, Hansen, D, Pallisgaard, N, Hasselbalch, H C & Ottesen, J T 2020, ' Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms ', Cancer Medicine, vol. 9, no. 6, pp. 2039-2051 . https://doi.org/10.1002/cam4.2741
Pedersen, R K, Andersen, M, Knudsen, T A, Sajid, Z, Gudmand-Hoeyer, J, Dam, M J B, Skov, V, Kjær, L, Ellervik, C, Larsen, T S, Hansen, D, Pallisgaard, N, Hasselbalch, H C & Ottesen, J T 2020, ' Data-driven analysis of JAK2 V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms ', Cancer Medicine, vol. 9, no. 6, pp. 2039-2051 . https://doi.org/10.1002/cam4.2741
Cancer Medicine
Pedersen, R K, Andersen, M, Knudsen, T A, Sajid, Z, Gudmand-Hoeyer, J, Dam, M J B, Skov, V, Kjær, L, Ellervik, C, Larsen, T S, Hansen, D, Pallisgaard, N, Hasselbalch, H C & Ottesen, J T 2020, ' Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms ', Cancer Medicine, vol. 9, no. 6, pp. 2039-2051 . https://doi.org/10.1002/cam4.2741
Pedersen, R K, Andersen, M, Knudsen, T A, Sajid, Z, Gudmand-Hoeyer, J, Dam, M J B, Skov, V, Kjær, L, Ellervik, C, Larsen, T S, Hansen, D, Pallisgaard, N, Hasselbalch, H C & Ottesen, J T 2020, ' Data-driven analysis of JAK2 V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms ', Cancer Medicine, vol. 9, no. 6, pp. 2039-2051 . https://doi.org/10.1002/cam4.2741
Treatment with PEGylated interferon‐alpha2 (IFN) of patients with essential thrombocythemia and polycythemia vera induces major molecular remissions with a reduction in the JAK2V617F allele burden to undetectable levels in a subset of patients. A f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c82d7f60adb58a0da48355d6e2156f
https://doaj.org/article/131ca176f70243be969c1f07922ecf78
https://doaj.org/article/131ca176f70243be969c1f07922ecf78
Autor:
Rasmus Kristoffer Pedersen, Morten Andersen, Vibe Skov, Lasse Kjær, Hans C Hasselbalch, Johnny T Ottesen, Thomas Stiehl
Publikováno v:
Stem cells 41(3), 260-270 (2023). doi:10.1093/stmcls/sxac079
Stem cells (2022). doi:10.1093/stmcls/sxac079
Published by Oxford University Press, Oxford
Published by Oxford University Press, Oxford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faa70b8c201a60d4b6463d4217ab290
Autor:
Franziska Hildebrandt, Mathias Mølbak Ingholt, Tzu Tung Chen, Lone Simonsen, Rasmus Kristoffer Pedersen
Background A now-extinct strain of Plasmodium vivax was endemic in northern Europe until the early 20th century. In light of the emergence of other vector borne diseases in Europe under climate change, temperate climate malaria warrants a re-examinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd70f4abbb73ccb4be49ada74102d188
https://doi.org/10.21203/rs.3.rs-812362/v1
https://doi.org/10.21203/rs.3.rs-812362/v1
Autor:
Hans Carl Hasselbalch, Johnny T. Ottesen, Vibe Skov, Rasmus Kristoffer Pedersen, Lasse Kjær, Trine Alma Knudsen, Morten Andersen, Marc John Bordier Dam
Publikováno v:
European journal of haematologyREFERENCES. 107(6)
BACKGROUND Hydroxyurea (HU) treatment of patients with essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) (MPNs) normalizes elevated blood cell counts within weeks in the large majority of patients. Studies on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c2352a36f123461db963c68c38b9c6
https://pubmed.ncbi.nlm.nih.gov/34411333
https://pubmed.ncbi.nlm.nih.gov/34411333
Autor:
Marc John Bordier Dam, Lasse Kjær, Morten Andersen, Trine Alma Knudsen, Johnny T. Ottesen, Vibe Skov, Rasmus Kristoffer Pedersen
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2119, p 2119 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2119, p 2119 (2020)
(1) Background: myeloproliferative neoplasms (MPNs) are slowly developing hematological cancers characterized by few driver mutations, with JAK2V617F being the most prevalent. (2) Methods: using mechanism-based mathematical modeling (MM) of hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f357121df1de861cf7534f45f17831
Publikováno v:
Journal of Theoretical Biology. 518:110620
Human blood cell production is maintained by hematopoietic stem cells (HSC) which give rise to all types of mature blood cells. Experimental observation of HSC in their physiologic bone-marrow microenvironment, the so-called stem cell niche, is chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d319d5dc21a86fcab5322b1de601fac3
https://doi.org/10.1016/j.jtbi.2021.110620
https://doi.org/10.1016/j.jtbi.2021.110620
Autor:
Rasmus Kristoffer Pedersen, Lasse Kjær, Trine Alma Knudsen, Hans Carl Hasselbalch, Niels Pallisgaard, Johnny T. Ottesen, Vibe Skov, Morten Andersen, Johanne Gudmand-Hoeyer, Zamra Sajid, Katrine O. Bangsgaard
Publikováno v:
Ottesen, J T, Pedersen, R K, Sajid, Z, Gudmand-hoeyer, J, Bangsgaard, K O, Skov, V, Kjær, L, Knudsen, T A, Pallisgaard, N, Hasselbalch, H C & Andersen, M 2019, ' Bridging blood cancers and inflammation : The reduced Cancitis model ', Journal of Theoretical Biology, vol. 465, pp. 90-108 . https://doi.org/10.1016/j.jtbi.2019.01.001
A novel mechanism-based model - the Cancitis model - describing the interaction of blood cancer and the inflammatory system is proposed, analyzed and validated. The immune response is divided into two components, one where the elimination rate of mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040e83b30d765c696812215667292b70
https://pubmed.ncbi.nlm.nih.gov/30615883
https://pubmed.ncbi.nlm.nih.gov/30615883
Autor:
Torben A Kruse, Johnny T. Ottesen, Vibe Skov, Johanne Gudmand-Hoeyer, Niels Pallisgaard, Morten Andersen, Jesper T. Troelsen, Rasmus Kristoffer Pedersen, Christina Ellervik, Hans Carl Hasselbalch, Mads Thomassen, Zamra Sajid, Lasse Kjær
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183620 (2017)
PLoS ONE
Andersen, M, Sajid, Z, Pedersen, R K, Gudmand-Hoeyer, J, Ellervik, C, Skov, V, Kjær, L, Pallisgaard, N, Kruse, T A, Thomassen, M, Troelsen, J, Hasselbalch, H C & Ottesen, J T 2017, ' Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development ', PLOS ONE, vol. 12, no. 8, e0183620 . https://doi.org/10.1371/journal.pone.0183620
Andersen, M, Sajid, Z, Pedersen, R K, Gudmand-hoeyer, J, Ellervik, C, Skov, V, Kjær, L, Pallisgaard, N, Kruse, T A, Thomassen, M, Troelsen, J, Hasselbalch, H C & Ottesen, J T 2017, ' Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development ', PLOS ONE, vol. 12, no. 8, e0183620 . https://doi.org/10.1371/journal.pone.0183620
PLoS ONE
Andersen, M, Sajid, Z, Pedersen, R K, Gudmand-Hoeyer, J, Ellervik, C, Skov, V, Kjær, L, Pallisgaard, N, Kruse, T A, Thomassen, M, Troelsen, J, Hasselbalch, H C & Ottesen, J T 2017, ' Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development ', PLOS ONE, vol. 12, no. 8, e0183620 . https://doi.org/10.1371/journal.pone.0183620
Andersen, M, Sajid, Z, Pedersen, R K, Gudmand-hoeyer, J, Ellervik, C, Skov, V, Kjær, L, Pallisgaard, N, Kruse, T A, Thomassen, M, Troelsen, J, Hasselbalch, H C & Ottesen, J T 2017, ' Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development ', PLOS ONE, vol. 12, no. 8, e0183620 . https://doi.org/10.1371/journal.pone.0183620
The chronic Philadelphia-negative myeloproliferative neoplasms (MPNs) are acquired stem cell neoplasms which ultimately may transform to acute myelogenous leukemia. Most recently, chronic inflammation has been described as an important factor for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea25ece937cee15e0569fdd7f6d1f0f4
http://europepmc.org/articles/PMC5578482?pdf=render
http://europepmc.org/articles/PMC5578482?pdf=render
Autor:
Christina Ellervik, Marc J. B. Dam, Hans Carl Hasselbalch, Zamra Sajid, Lasse Kjær, Johnny T. Ottesen, Rasmus Kristoffer Pedersen, Vibe Skov, Morten Andersen, Trine Alma Knudsen
Publikováno v:
Blood. 134:2972-2972
Background: Treatment of polycythemia vera (PV) patients with hydroxyurea (HU) normalizes elevated blood cell counts within weeks in the large majority of patients. Studies on the impact of HU upon the kinetics of the JAK2V617F allele burden, leukocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d137dc0ee90f7bf44dcbc460a42c9b
https://doi.org/10.1182/blood-2019-126819
https://doi.org/10.1182/blood-2019-126819