QTc interval in patients with schizophrenia receiving antipsychotic treatment as monotherapy or polypharmacy

Autor: Thibault Johan Mørk, Anne Grethe Viuff, Povl Munk-Jørgensen, Anja Friis Elliott, Nikolaj Juul Madsen, Jens Cosedis Nielsen, Peter Hjorth, Mikkel Højlund, Rasmus Jeppesen, Thomas Christensen

Publikováno v: Elliott, A, Mørk, T J, Højlund, M, Christensen, T, Jeppesen, R, Madsen, N, Viuff, A G, Hjorth, P, Nielsen, J C & Munk-Jørgensen, P 2018, ' QTc interval in patients with schizophrenia receiving antipsychotic treatment as monotherapy or polypharmacy ', C N S Spectrums, vol. 23, no. 4, pp. 278-283 . https://doi.org/10.1017/S1092852917000402
Elliott, A F, Johan Mørk, T, Højlund, M, Christensen, T, Jeppesen, R, Madsen, N, Grethe Viuff, A, Hjorth, P, Cosedis Nielsen, J & Munk-Jørgensen, P 2018, ' QTc interval in patients with schizophrenia receiving antipsychotic treatment as monotherapy or polypharmacy ', CNS Spectrums, vol. 23, no. 4, pp. 278-283 . https://doi.org/10.1017/S1092852917000402

ObjectiveAntipsychotics are associated with a polymorphic ventricular tachycardia, torsades de pointes, which, in the worst case, can lead to sudden cardiac death. The QT interval corrected for heart rate (QTc) is used as a clinical proxy for torsade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f2baba6304a6ee341122d1644f483f
https://doi.org/10.1017/s1092852917000402