Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rasmani, Hazra"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/73365c3551514d8ea13e44a234e769bb
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Glioblastoma poses a formidable challenge among primary brain tumors: its tumorigenic stem cells, capable of self-renewal, proliferation, and differentiation, contribute substantially to tumor initiation and therapy resistance. These glioblastoma ste
Externí odkaz:
https://doaj.org/article/a6bc666b3680452f8b1406a4b419f237
Autor:
Rasmani Hazra, David L. Spector
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Whole-mount single-molecule RNA fluorescence in situ hybridization (smRNA FISH) in combination with immunofluorescence (IF) offers great potential to study long non-coding RNAs (lncRNAs): their subcellular localization, their interactions with protei
Externí odkaz:
https://doaj.org/article/d44c5569340c4c82a2bdfd764d8360a1
Publikováno v:
bioRxiv
Glioblastoma multiforme (GBM) is an aggressive, heterogeneous grade IV brain tumor. Glioblastoma stem cells (GSCs) initiate the tumor and are known culprits of therapy resistance. Mounting evidence has demonstrated a regulatory role of long non-codin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1dee6b1d6a4c80c0ad24f0db64cd5d
https://doi.org/10.1101/2023.01.20.524887
https://doi.org/10.1101/2023.01.20.524887
Autor:
Rasmani Hazra, Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael M. Shen, John Erby Wilkinson, Scott K. Lyons, David L. Spector
SummaryThe mammalian genome encodes thousands of long non-coding RNAs (lncRNAs) that are developmentally regulated and differentially expressed across tissues, suggesting possible roles in cellular differentiation. Despite this expression pattern, li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655328f610de4ecca9e239c789299653
https://doi.org/10.1101/2021.12.20.473435
https://doi.org/10.1101/2021.12.20.473435
Autor:
Rasmani Hazra, Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael M. Shen, John Erby Wilkinson, Scott K. Lyons, David L. Spector
Publikováno v:
Developmental cell. 57(21)
The mammalian genome encodes thousands of long non-coding RNAs (lncRNAs), many of which are developmentally regulated and differentially expressed across tissues, suggesting their potential roles in cellular differentiation. Despite this expression p
Autor:
Rasmani Hazra, Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael Shen, John Erby Wilkinson, Scott Lyons, David Spector
Publikováno v:
SSRN Electronic Journal.
Autor:
Charles M. Allan, Dannielle H. Upton, Rasmani Hazra, Reena Desai, David J. Handelsman, Mark Jimenez
Publikováno v:
Endocrinology. 155:1120-1130
We determined the functional role of the Sertoli cell glucocorticoid receptor (GR) in vivo using a transgenic Cre-loxP approach to conditionally disrupt GR expression. Sertoli cell GR knockout (SCGRKO) was shown by absent Sertoli cell-specific GR imm
Publikováno v:
Endocrinology. 154:3410-3422
We recently created a mouse model displaying precocious Sertoli cell (SC) and spermatogenic development induced by SC-specific transgenic androgen receptor expression (TgSCAR). Here we reveal that TgSCAR regulates the development, function, and absol
Autor:
Charles M. Allan, Rasmani Hazra, David J. Handelsman, Lisa Corcoran, Mat Robson, Dannielle H. Upton, Kirsten J. McTavish
Publikováno v:
Molecular Endocrinology. 27:12-24
Sertoli cell (SC) androgen receptor (AR) activity is vital for spermatogenesis. We created a unique gain-of-function transgenic (Tg) mouse model to determine the temporal role of SCAR expression in testicular development. The SC-specific rat Abpa pro