Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rashmiparvathi Keshara"'
Autor:
Carla A. Gonçalves, Michael Larsen, Sascha Jung, Johannes Stratmann, Akiko Nakamura, Marit Leuschner, Lena Hersemann, Rashmiparvathi Keshara, Signe Perlman, Lene Lundvall, Lea Langhoff Thuesen, Kristine Juul Hare, Ido Amit, Anne Jørgensen, Yung Hae Kim, Antonio del Sol, Anne Grapin-Botton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
From single-cell transcriptome analyses to defining culture media for spheroids, the authors provide a census of information to understand the development of human pancreatic progenitors. This approach identifies signalling pathways (EGF and FGF) reg
Externí odkaz:
https://doaj.org/article/4dd4448416d0483cbbb89a084390dda1
Publikováno v:
Annual review of cell and developmental biology. 38
Organoids are miniaturized and simplified versions of an organ produced in vitro from stem or progenitor cells. They are used as a model system consisting of multiple cell types forming an architecture relevant to the organ and carrying out the funct
Autor:
Yung Hae Kim, Anne Grapin-Botton, Rashmiparvathi Keshara, Signe Perlman, Sascha Jung, Antonio del Sol, Michael Larsen, Carla A C Gonçalves, Akiko Nakamura, Kristine J. Hare, Lene Lundvall, Lena Hersemann, Johannes Stratmann, Ido Amit, Lea Langhoff Thuesen, Anne Jørgensen, Marit Leuschner
Publikováno v:
Goncalves, C A, Larsen, M, Jung, S, Stratmann, J, Nakamura, A, Leuschner, M, Hersemann, L, Keshara, R, Perlman, S, Lundvall, L, Thuesen, L L, Hare, K J, Amit, I, Jørgensen, A, Kim, Y H, del Sol, A & Grapin-Botton, A 2021, ' A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion ', Nature Communications, vol. 12, 3144 . https://doi.org/10.1038/s41467-021-23295-6
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Human organogenesis remains relatively unexplored for ethical and practical reasons. Here, we report the establishment of a single-cell transcriptome atlas of the human fetal pancreas between 7 and 10 post-conceptional weeks of development. To interr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015b3dc2a4cab00c0944a7f613c56104
https://doi.org/10.21203/rs.3.pex-1430/v1
https://doi.org/10.21203/rs.3.pex-1430/v1
Publikováno v:
Lewis, A, Keshara, R, Kim, Y H & Grapin-Botton, A 2021, ' Self-organization of organoids from endoderm-derived cells ', Journal of Molecular Medicine, vol. 99, pp. 449-462 . https://doi.org/10.1007/s00109-020-02010-w
Journal of Molecular Medicine (Berlin, Germany)
Journal of Molecular Medicine (Berlin, Germany)
Organoids constitute biological systems which are used to model organ development, homeostasis, regeneration, and disease in vitro and hold promise for use in therapy. Reflecting in vivo development, organoids form from tissue cells or pluripotent st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2bb4fdc9bb3d040b02e0813e0b7cf2
https://curis.ku.dk/portal/da/publications/selforganization-of-organoids-from-endodermderived-cells(d89af857-8abe-4c7a-bd4f-3ca99f673954).html
https://curis.ku.dk/portal/da/publications/selforganization-of-organoids-from-endodermderived-cells(d89af857-8abe-4c7a-bd4f-3ca99f673954).html