Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Rashmi S Hegde"'
Autor:
Kunjan Patel, Arnaud P Giese, J M Grossheim, Rashmi S Hegde, Maria Delio, Joy Samanich, Saima Riazuddin, Gregory I Frolenkov, Jinlu Cai, Zubair M Ahmed, Bernice E Morrow
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141259 (2015)
Externí odkaz:
https://doaj.org/article/30a149114bd04a568cf6c7798c792084
Autor:
Kunjan Patel, Arnaud P Giese, J M Grossheim, Rashmi S Hegde, Maria Delio, Joy Samanich, Saima Riazuddin, Gregory I Frolenkov, Jinlu Cai, Zubair M Ahmed, Bernice E Morrow
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0133082 (2015)
Hearing loss is a complex disorder caused by both genetic and environmental factors. Previously, mutations in CIB2 have been identified as a common cause of genetic hearing loss in Pakistani and Turkish populations. Here we report a novel (c.556C>T;
Externí odkaz:
https://doaj.org/article/7c25e98ab1604238ab40b31e9ec90e09
Autor:
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The Eyes Absent proteins (EYA1-4) are a biochemically unique group of tyrosine phosphatases known to be tumour-promoting across a range of cancer types. To date, the targets of EYA phosphatase activity remain largely uncharacterised. Here, w
Externí odkaz:
https://doaj.org/article/c6f9e1aee6c04251a8ad3f7b91d37b75
Autor:
Ram Naresh Pandey, Tim Sen Wang, Emmanuel Tadjuidje, Matthew G McDonald, Allan E Rettie, Rashmi S Hegde
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84582 (2013)
The tyrosine phosphatase activity of the phosphatase-transactivator protein Eyes Absent (EYA) is angiogenic through its roles in endothelial cell migration and tube formation. Benzbromarone, a known anti-gout agent, was previously identified as an in
Externí odkaz:
https://doaj.org/article/7a4d07bcf68a464ca9dff25cd832a408
Autor:
Emmanuel Tadjuidje, Tim Sen Wang, Ram Naresh Pandey, Saulius Sumanas, Richard A Lang, Rashmi S Hegde
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34806 (2012)
Eyes Absents (EYA) are multifunctional proteins best known for their role in organogenesis. There is accumulating evidence that overexpression of EYAs in breast and ovarian cancers, and in malignant peripheral nerve sheath tumors, correlates with tum
Externí odkaz:
https://doaj.org/article/edbe460a6211452faa12e1ff35eeb7e9
Autor:
Virgilio G Ponferrada, Jieqing Fan, Jefferson E Vallance, Shengyong Hu, Aygun Mamedova, Scott A Rankin, Matthew Kofron, Aaron M Zorn, Rashmi S Hegde, Richard A Lang
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32635 (2012)
In multicellular organisms, morphogenesis is a highly coordinated process that requires dynamically regulated adhesion between cells. An excellent example of cellular morphogenesis is the formation of the neural tube from the flattened epithelium of
Externí odkaz:
https://doaj.org/article/7dbbfd1175dd4fa6bddf37c76a33c611
Autor:
Ming Tan, Ming Xia, Yutao Chen, Weiming Bu, Rashmi S Hegde, Jarek Meller, Xuemei Li, Xi Jiang
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5058 (2009)
Human noroviruses are the major viral pathogens of epidemic acute gastroenteritis. These genetically diverse viruses comprise two major genogroups (GI and GII) and approximately 30 genotypes. Noroviruses recognize human histo-blood group antigens (HB
Externí odkaz:
https://doaj.org/article/41736aa208fb4b7ca9c5bcbc0f5365f6
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-12 (2023)
Abstract The insulin-like growth factor receptor (IGF-1R) was among the most intensively pursued kinase targets in oncology. However, even after a slew of small-molecule and antibody therapeutics reached clinical trials for a range of solid tumors, t
Externí odkaz:
https://doaj.org/article/99850203b21a4405a66107136855d0f2
Autor:
Rashmi S. Hegde, Joseph G. Pressey, Sara Szabo, Tanya V. Kalin, David Milewski, Kaushik Roychoudhury, Ram Naresh Pandey, Yuhua Wang
Figure S3 documents how loss of Eya3 or BZ treatment affects multicellular tumor spheroids generated with A673 and RD-ES cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e94d198ec96e9ff91b49bb355f263f0
https://doi.org/10.1158/1535-7163.22522564.v1
https://doi.org/10.1158/1535-7163.22522564.v1
Autor:
Rashmi S. Hegde, Joseph G. Pressey, Sara Szabo, Tanya V. Kalin, David Milewski, Kaushik Roychoudhury, Ram Naresh Pandey, Yuhua Wang
EWSR1/FLI1, the most common fusion gene in Ewing sarcoma, upregulates expression of the Eyes Absent 3 (EYA3) transactivator–phosphatase protein. The purpose of this study was to investigate molecular and cellular mechanisms through which EYA3 might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b437ac795ba27d24d211c13a3719b8
https://doi.org/10.1158/1535-7163.c.6543436
https://doi.org/10.1158/1535-7163.c.6543436