Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rashmi J Kumar"'
Autor:
Hui Xiao Chao, Randy I Fakhreddin, Hristo K Shimerov, Katarzyna M Kedziora, Rashmi J Kumar, Joanna Perez, Juanita C Limas, Gavin D Grant, Jeanette Gowen Cook, Gaorav P Gupta, Jeremy E Purvis
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 3, Pp 1-19 (2019)
Abstract The cell cycle is canonically described as a series of four consecutive phases: G1, S, G2, and M. In single cells, the duration of each phase varies, but the quantitative laws that govern phase durations are not well understood. Using time
Externí odkaz:
https://doaj.org/article/81290e9fcfee4492b0f34caf81dfef6d
Autor:
Wanjuan Feng, Dennis A. Simpson, Juan Carvajal-Garcia, Brandon A. Price, Rashmi J. Kumar, Lisle E. Mose, Richard D. Wood, Naim Rashid, Jeremy E. Purvis, Joel S. Parker, Dale A. Ramsden, Gaorav P. Gupta
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Polymerase theta is a widely conserved DNA polymerase that mediates Theta Mediated End Joining. Here authors present a synthetic lethal CRISPR screen to identify DDR gene mutations that induce cellular addiction to Pol theta.
Externí odkaz:
https://doaj.org/article/566f9084f7004b948bfb7d7d81816fbb
Autor:
Katerina D. Fagan-Solis, Dennis A. Simpson, Rashmi J. Kumar, Luciano G. Martelotto, Lisle E. Mose, Naim U. Rashid, Alice Y. Ho, Simon N. Powell, Y. Hannah Wen, Joel S. Parker, Jorge S. Reis-Filho, John H.J. Petrini, Gaorav P. Gupta
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1385-1399.e7 (2020)
Summary: The Mre11-Rad50-Nbs1 complex is a DNA double-strand break sensor that mediates a tumor-suppressive DNA damage response (DDR) in cells undergoing oncogenic stress, yet the mechanisms underlying this effect are poorly understood. Using a genet
Externí odkaz:
https://doaj.org/article/c748e1c4c3444689abb982bb24303a91
Autor:
Alison R. Mercer-Smith, Andrew Buckley, Alain Valdivia, Wulin Jiang, Morrent Thang, Noah Bell, Rashmi J. Kumar, Hunter N. Bomba, Alex S. Woodell, Jie Luo, Scott R. Floyd, Shawn D. Hingtgen
Publikováno v:
Stem Cell Reviews and Reports. 18:2474-2493
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d667e2b5546aac16e102a5a7fc1b57ae
https://doi.org/10.1007/s12015-022-10375-3
https://doi.org/10.1007/s12015-022-10375-3
Autor:
Min-Guk Cho, Rashmi J. Kumar, Chien-Chu Lin, Joshua A. Boyer, Jamshaid A. Shahir, Katerina Fagan-Solis, Dennis A. Simpson, Cheng Fan, Christine E. Foster, Anna M. Goddard, Qinhong Wang, Ying Wang, Alice Y. Ho, Pengda Liu, Charles M. Perou, Qi Zhang, Robert K. McGinty, Jeremy E. Purvis, Gaorav P. Gupta
Oncogene-induced replication stress generates endogenous DNA damage that activates cGAS/STING-mediated innate immune signaling and tumor suppression1-3. However, the mechanism for cGAS activation by endogenous DNA damage remains enigmatic, particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91194156b51e8c8ee91b4ac4eb3cf325
https://doi.org/10.1101/2022.12.09.519750
https://doi.org/10.1101/2022.12.09.519750
Autor:
Soha Bazyar, Edward Timothy O’Brien, Thad Benefield, Victoria R. Roberts, Rashmi J. Kumar, Gaorav P. Gupta, Otto Zhou, Yueh Z. Lee
Publikováno v:
Cancers; Volume 14; Issue 1; Pages: 155
Cancers, Vol 14, Iss 155, p 155 (2022)
Cancers
Cancers, Vol 14, Iss 155, p 155 (2022)
Cancers
Simple Summary Half of all cancer patients receive radiation therapy during their course of treatment. The destructive effects of radiation on normal tissue causes side effects that significantly affect the patient’s quality of life. Microplanar ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44505eddc1b81345631afccbf4b1034e