Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rashmi Dahiya"'
Autor:
Qing Hu, Jose Espejo Valle-Inclán, Rashmi Dahiya, Alison Guyer, Alice Mazzagatti, Elizabeth G. Maurais, Justin L. Engel, Huiming Lu, Anthony J. Davis, Isidro Cortés-Ciriano, Peter Ly
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Mitotic errors generate micronuclei entrapping mis-segregated chromosomes, which are susceptible to catastrophic fragmentation through chromothripsis. The reassembly of fragmented chromosomes by error-prone DNA double-strand break (DSB) repa
Externí odkaz:
https://doaj.org/article/e794b1d33de7411e96a1a911463a4866
Autor:
Sonam Roy, Taj Mohammad, Preeti Gupta, Rashmi Dahiya, Shahnaz Parveen, Suaib Luqman, Gulam Mustafa Hasan, Md. Imtaiyaz Hassan
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21550-21560 (2020)
Externí odkaz:
https://doaj.org/article/9ece46602d9b4633b29c6ed0d4e6d49b
Autor:
Rashmi Dahiya, Taj Mohammad, Mohamed F. Alajmi, Md. Tabish Rehman, Gulam Mustafa Hasan, Afzal Hussain, Md. Imtaiyaz Hassan
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 882 (2020)
Aging represents a significant biological process having strong associations with cancer, diabetes, and neurodegenerative and cardiovascular disorders, which leads to progressive loss of cellular functions and viability. Astonishingly, age-related di
Externí odkaz:
https://doaj.org/article/c88533db078a4acab7204bc7e28f9c9e
Autor:
Yu-Fen Lin, Qing Hu, Alice Mazzagatti, Jose Espejo Valle-Inclán, Elizabeth G. Maurais, Rashmi Dahiya, Alison Guyer, Jacob T. Sanders, Justin L. Engel, Giaochau Nguyen, Daniel Bronder, Samuel F. Bakhoum, Isidro Cortés-Ciriano, Peter Ly
Publikováno v:
Nature.
Complex genome rearrangements can be generated by the catastrophic pulverization of missegregated chromosomes trapped within micronuclei through a process known as chromothripsis1–5. As each chromosome contains a single centromere, it remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3cac4ddbefcb1190c1143b04c76bd02
https://doi.org/10.1038/s41586-023-05974-0
https://doi.org/10.1038/s41586-023-05974-0
Autor:
Frank M. Mason, Emily S. Kounlavong, Anteneh T. Tebeje, Rashmi Dahiya, Tiffany Guess, Logan Vlach, Stephen R. Norris, Courtney A. Lovejoy, Ruhee Dere, Ryoma Ohi, Peter Ly, Cheryl L. Walker, W. Kimryn Rathmell
SummaryFactors governing the faithful replication of chromosomes are essential for cellular and genomic integrity. While a variety of mechanisms to manage breaks and promote repair of DNA are widely recognized, epigenetic landmarks that preserve telo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0254fa548e9d47cb41bf2f2df61c525
https://doi.org/10.1101/2022.10.25.513694
https://doi.org/10.1101/2022.10.25.513694
Autor:
Gulam Mustafa Hasan, Sonam Roy, Rashmi Dahiya, Taj Mohammad, Preeti Gupta, Suaib Luqman, Imtaiyaz Hassan, Shahnaz Parveen
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21550-21560 (2020)
ACS Omega
ACS Omega
The sphingosine kinase-1/sphingosine-1-phosphate pathway is linked with the cancer progression and survival of the chemotherapy-challenged cells. Sphingosine kinase-1 (SphK1) has emerged as an attractive drug target, but their inhibitors from natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc02d75630691e0d11af68610f2eb10a
https://doi.org/10.1021/acsomega.0c02165
https://doi.org/10.1021/acsomega.0c02165
Autor:
Rashmi Dahiya, Afzal Hussain, Md. Imtaiyaz Hassan, Taj Mohammad, Sonam Roy, Mohamed F. Alajmi, Omar M. Noman, Preeti Gupta
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Sphingosine kinase 1 (SphK1) has recently gained attention as a potential drug target for its association with cancer and other inflammatory diseases. Here, we have investigated the binding affinity of dietary phytochemicals viz., ursolic acid, capsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704911b9eb5a8b212fa19cf435d837b8
http://link.springer.com/article/10.1038/s41598-019-55199-3
http://link.springer.com/article/10.1038/s41598-019-55199-3
Autor:
Anzarul Haque, Faizan Ahmad, Sonam Roy, Asimul Islam, Parvez Khan, Saleha Anwar, Preeti Gupta, Syed Naqui Kazim, Md. Imtaiyaz Hassan, Rashmi Dahiya, Taj Mohammad
Publikováno v:
International Journal of Biological Macromolecules. 136:1076-1085
Pyruvate dehydrogenase kinase 3 (PDK3) is a mitochondrial protein, has recently been considered as a potential pharmacological target for varying types of cancer. Here, we report the binding mechanism of quercetin to the PDK3 by using molecular docki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a4a092d2369b7edf0cc38edd877f58
https://doi.org/10.1016/j.ijbiomac.2019.06.158
https://doi.org/10.1016/j.ijbiomac.2019.06.158
Publikováno v:
Semin Cell Dev Biol
Cancer genomes frequently harbor structural chromosomal rearrangements that disrupt the linear DNA sequence order and copy number. To date, diverse classes of structural variants have been identified across multiple cancer types. These aberrations sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bdccedd474c60c2b4284d53c450fc2
https://pubmed.ncbi.nlm.nih.gov/33824062
https://pubmed.ncbi.nlm.nih.gov/33824062
Publikováno v:
Systems and Synthetic Immunology ISBN: 9789811533495
Immunotherapy is a breakthrough in the potential treatment of cancer as well as preventing future relapses by stimulating the immune system in the recognition and killing of cancer cells. Numerous strategies are ongoing in the clinical laboratories f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2bec79f55e84ad25276ab538cb6d95e
https://doi.org/10.1007/978-981-15-3350-1_3
https://doi.org/10.1007/978-981-15-3350-1_3