The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria.

Autor: Ojewunmi OO; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom., Adeyemo TA; Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria., Oyetunji AI; Sickle Cell Foundation Nigeria, Ishaga Road, Idi-Araba, P.O. Box 3463, Lagos, Nigeria., Inyang B; Department of Medical Biochemistry, College of Health Sciences, University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria., Akinrindoye A; Sickle Cell Foundation Nigeria, Ishaga Road, Idi-Araba, P.O. Box 3463, Lagos, Nigeria.; School of Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, United Kingdom., Mkumbe BS; Department of Biochemistry and Molecular Biology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Department of Artificial Intelligence and Innovative Medicine, Tohoku University Graduate School of Medicine, 980-8573, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan., Gardner K; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.; Clinical Haematology, Haematology and Oncology Directorate, Guy's Hospital, Great Maze Pond, London SE1 9RT, United Kingdom., Rooks H; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom., Brewin J; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.; Department of Haematological Medicine, King's College Hospital, London SE5 9RS, United Kingdom., Patel H; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London SE5 8AB, United Kingdom., Lee SH; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London SE5 8AB, United Kingdom., Chung R; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 16 De Crespigny Park, London SE5 8AB, United Kingdom., Rashkin S; St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, United States., Kang G; St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, United States., Chianumba R; Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria., Sangeda R; Department of Pharmaceutical Microbiology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, Tanzania., Mwita L; Department of Pharmaceutical Microbiology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, Tanzania., Isa H; Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria.; Department of Haematology and Blood Transfusion, University of Abuja Teaching Hospital, Gwagwalada, P.M.B. 228, Gwagwalada, FCT Abuja, Nigeria., Agumadu UN; Department of Paediatrics, College of Health Sciences, University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria., Ekong R; Research Department of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, United Kingdom., Faruk JA; Department of Paediatrics, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Jamoh BY; Department of Internal Medicine, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Adebiyi NM; Department of Paediatrics, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Umar IA; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Sokoto Road, Samaru, P.M.B 006, Zaria, Nigeria., Hassan A; Department of Haematology and Blood Transfusion, Ahmadu Bello University, Sokoto Road, Samaru, P.M.B 006, Zaria, Nigeria., Grace C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Centre for Human Genetics, Roosevelt Drive, Oxford OX37BN, United Kingdom., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Centre for Human Genetics, Roosevelt Drive, Oxford OX37BN, United Kingdom., Inusa BPD; Evelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, Westminster Bridge Rd, London SE1 7EH, United Kingdom., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, United Kingdom., Nkya S; Department of Biochemistry and Molecular Biology, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Tanzania Human Genetics Organisation, Sickle Cell Centre, 1 Kipalapala Street, Dar es Salaam, Tanzania.; Sickle Cell Program, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Science, P.O. Box 65001, Dar es Salaam, Tanzania., Makani J; Sickle Cell Program, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, United Nations Rd, Dar es Salaam, Tanzania.; Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Science, P.O. Box 65001, Dar es Salaam, Tanzania.; Centre for Haematology, Department of Immunology & Inflammation, Imperial College London, Commonwealth Building, Hammersmith Campus, Du Cane Rd, London W12 0NN, United Kingdom., Ahmad HR; Department of Paediatrics, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, P.M.B 006, Zaria, Nigeria., Nnodu O; Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, Mohammed Maccido Road, Airport Road, P.M.B 117, Abuja, Nigeria.; Department of Haematology and Blood Transfusion, University of Abuja Teaching Hospital, Gwagwalada, P.M.B. 228, Gwagwalada, FCT Abuja, Nigeria., Strouboulis J; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom., Menzel S; School of Cancer and Pharmaceutical Sciences, King's College London, 123 Coldharbour Lane, London SE5 9NU, United Kingdom.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2024 May 04; Vol. 33 (10), pp. 919-929.

Optimal sequencing strategies for identifying disease-associated singletons.

Autor: Rashkin S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America., Jun G; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Chen S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2017 Jun 22; Vol. 13 (6), pp. e1006811. Date of Electronic Publication: 2017 Jun 22 (Print Publication: 2017).

Possible impact of HLA class I and class II on malignancies driven by a single germ‐line BRCA1 mutation.

Autor: Ivanova, Milena¹ (AUTHOR) mivanova@intech.bg, Ormandjieva, Anastasia¹ (AUTHOR), Dodova, Rumyana² (AUTHOR), Kaneva, Radka² (AUTHOR), Shivarov, Velizar³ (AUTHOR) vshivarov@abv.bg

Publikováno v: International Journal of Immunogenetics. Oct2023, Vol. 50 Issue 5, p243-248. 6p.

Whole genome sequences of 70 indigenous Ethiopian cattle.

Autor: Ayalew, Wondossen, Xiaoyun, Wu, Tarekegn, Getinet Mekuriaw, Naboulsi, Rakan, Sisay Tessema, Tesfaye, Van Damme, Renaud, Bongcam-Rudloff, Erik, Chu, Min, Liang, Chunnian, Edea, Zewdu, Enquahone, Solomon, Ping, Yan

Publikováno v: Scientific Data; 6/5/2024, Vol. 11 Issue 1, p1-7, 7p

An atlas of genetic effects on cellular composition of the tumor microenvironment.

Autor: Cai Y; Department of Epidemiology and Biostatistics, School of Public Health, Research Center of Public Health, Renmin hospital of Wuhan University, Department of Gastrointestinal Oncology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China., Lu Z; Department of Epidemiology and Biostatistics, School of Public Health, Research Center of Public Health, Renmin hospital of Wuhan University, Department of Gastrointestinal Oncology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China., Chen C; Department of Epidemiology and Biostatistics, School of Public Health, Research Center of Public Health, Renmin hospital of Wuhan University, Department of Gastrointestinal Oncology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China., Zhu Y; Department of Epidemiology and Biostatistics, School of Public Health, Research Center of Public Health, Renmin hospital of Wuhan University, Department of Gastrointestinal Oncology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China., Chen Z; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Wu Z; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Peng J; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Zhu X; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Liu Z; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Li B; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Zhang M; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Huang J; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Li Y; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Liu Y; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Ma Q; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., He C; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Chen S; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Tian W; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Fan L; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Ning C; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Geng H; Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, China., Xu B; Cancer Center, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, China., Li H; Department of Gastrointestinal Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhu X; Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China., Fang J; Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China., Wang X; Department of Cancer Epidemiology, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Henan Engineering Research Center of Cancer Prevention and Control, Henan International Joint Laboratory of Cancer Prevention, Zhengzhou, China., Zhang S; Department of Cancer Epidemiology, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Henan Engineering Research Center of Cancer Prevention and Control, Henan International Joint Laboratory of Cancer Prevention, Zhengzhou, China., Jin M; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Huang C; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China., Yang X; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China., Tian J; Department of Epidemiology and Biostatistics, School of Public Health, Research Center of Public Health, Renmin hospital of Wuhan University, Department of Gastrointestinal Oncology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. tianjb@whu.edu.cn., Miao X; Department of Epidemiology and Biostatistics, School of Public Health, Research Center of Public Health, Renmin hospital of Wuhan University, Department of Gastrointestinal Oncology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. xpmiao@whu.edu.cn.; Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, China. xpmiao@whu.edu.cn.; Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China. xpmiao@whu.edu.cn.

Publikováno v: Nature immunology [Nat Immunol] 2024 Oct; Vol. 25 (10), pp. 1959-1975. Date of Electronic Publication: 2024 Sep 02.