Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Rashid O. Anarbaev"'
Autor:
Maria V. Sukhanova, Rashid O. Anarbaev, Ekaterina A. Maltseva, Mikhail M. Kutuzov, Olga I. Lavrik
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract The formation of nuclear biomolecular condensates is often associated with local accumulation of proteins at a site of DNA damage. The key role in the formation of DNA repair foci belongs to PARP1, which is a sensor of DNA damage and catalyz
Externí odkaz:
https://doaj.org/article/4345651c06e44d94a1015d06dede364d
Autor:
Natalia A. Lebedeva, Rashid O. Anarbaev, Ekaterina A. Maltseva, Maria V. Sukhanova, Nadejda I. Rechkunova, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6927 (2024)
Non-membrane compartments or biomolecular condensates play an important role in the regulation of cellular processes including DNA repair. Here, an ability of XRCC1, a scaffold protein involved in DNA base excision repair (BER) and single-strand brea
Externí odkaz:
https://doaj.org/article/b367756275d94f7d868901c96183ce06
Autor:
Konstantin N. Naumenko, Mariya V. Sukhanova, Loic Hamon, Tatyana A. Kurgina, Rashid O. Anarbaev, Aswin Mangerich, David Pastré, Olga I. Lavrik
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Y-box-binding protein 1 (YB-1) is a multifunctional protein involved in the regulation of gene expression. Recent studies showed that in addition to its role in the RNA and DNA metabolism, YB-1 is involved in the regulation of PARP1 activity, which c
Externí odkaz:
https://doaj.org/article/ba6af2193ffa4c1da6f06ac54d2a91b9
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13200 (2022)
Fused in sarcoma (FUS) is involved in the regulation of RNA and DNA metabolism. FUS participates in the formation of biomolecular condensates driven by phase transition. FUS is prone to self-aggregation and tends to undergo phase transition both with
Externí odkaz:
https://doaj.org/article/4c6544d5e49e41bd8c00b74951229935
Autor:
Nadezhda S. Dyrkheeva, Aleksandr S. Filimonov, Olga A. Luzina, Kristina A. Orlova, Irina A. Chernyshova, Tatyana E. Kornienko, Anastasia A. Malakhova, Sergey P. Medvedev, Alexandra L. Zakharenko, Ekaterina S. Ilina, Rashid O. Anarbaev, Konstantin N. Naumenko, Kristina V. Klabenkova, Ekaterina A. Burakova, Dmitry A. Stetsenko, Suren M. Zakian, Nariman F. Salakhutdinov, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11336 (2021)
Tyrosyl-DNA phosphodiesterase 1 (TDP1) catalyzes the cleavage of the phosphodiester bond between the tyrosine residue of topoisomerase 1 (TOP1) and the 3′ phosphate of DNA in the single-strand break generated by TOP1. TDP1 promotes the cleavage of
Externí odkaz:
https://doaj.org/article/ffbea489293848d98465c39d785114bf
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S26-S26 (2019)
Background: Base excision DNA repair (BER) is very efficient process that involves the action of many enzymes and accessory proteins to correct the most common DNA lesions usually induced by ionizing irradiation and oxidative stress. Coordination of
Externí odkaz:
https://doaj.org/article/17074e18245548c4a978296e74152851
Autor:
Elizaveta D. Gladkova, Ivan V. Nechepurenko, Roman A. Bredikhin, Arina A. Chepanova, Alexandra L. Zakharenko, Olga A. Luzina, Ekaterina S. Ilina, Nadezhda S. Dyrkheeva, Evgeniya M. Mamontova, Rashid O. Anarbaev, Jóhannes Reynisson, Konstantin P. Volcho, Nariman F. Salakhutdinov, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7162 (2020)
A series of berberine and tetrahydroberberine sulfonate derivatives were prepared and tested against the tyrosyl-DNA phosphodiesterase 1 (Tdp1) DNA-repair enzyme. The berberine derivatives inhibit the Tdp1 enzyme in the low micromolar range; this is
Externí odkaz:
https://doaj.org/article/261566b0c76343d483a7228239620a76
Autor:
Konstantin N. Naumenko, Mariya V. Sukhanova, Loic Hamon, Tatyana A. Kurgina, Rashid O. Anarbaev, Aswin Mangerich, David Pastré, Olga I. Lavrik
Publikováno v:
Frontiers in cell and developmental biology. 10
Y-box-binding protein 1 (YB-1) is a multifunctional protein involved in the regulation of gene expression. Recent studies showed that in addition to its role in the RNA and DNA metabolism, YB-1 is involved in the regulation of PARP1 activity, which c
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1867:297-305
Base excision repair (BER) involves many enzymes acting in a coordinated fashion at the most common types of DNA damage. The coordination is facilitated by interactions between the enzymes and accessory proteins, X-ray repair cross-complementing prot
Autor:
Olga I. Lavrik, Jochen Kuper, Rashid O. Anarbaev, Jeannette Kappenberger, I. O. Petruseva, Caroline Kisker, Natalia Naumenko
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The successful elimination of bulky DNA damages via the nucleotide excision repair (NER) system is largely determined by the damage recognition step. This step consists of primary recognition and verification of the damage. The TFIIH helicase XPD pla