Zobrazeno 1 - 10 of 29 pro vyhledávání: '"Rasha M Hussein"'
1
Akademický článek
Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners.
Autor: Rasha M Hussein, Ivor J Benjamin, Harm H Kampinga
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0126761 (2015)
HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Mutations in HSPB5 have been found to cause cataract, but are also associated with a subgroup of myofibrillar myopathies. Cells expressing each of these HSPB5 mu
Externí odkaz: https://doaj.org/article/e826ff61f2594cd1b984e38e7b4f16a1
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2
Akademický článek
Effect of quercetin-loaded poly (lactic-co-glycolic) acid nanoparticles on lipopolysaccharide-induced memory decline, oxidative stress, amyloidogenesis, neurotransmission, and Nrf2/HO-1 expression
Autor: Rasha M. Hussein, Mohamed A. Kandeil, Hatem M. Soliman, Ahmed A.G. El-Shahawy
Publikováno v: Heliyon, Vol 10, Iss 1, Pp e23527- (2024)
Neuroinflammation contributes to the pathogenesis of several neurodegenerative disorders. This study examined the neuroprotective effect of quercetin (QUR)-loaded poly (lactic-co-glycolic) acid (PLGA) nanoparticles (QUR NANO) against the neurotoxicit
Externí odkaz: https://doaj.org/article/235d0f0ddc944d739a45c46f511f6252
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6
Upregulation of miR-33 and miR-155 by gum acacia mitigates hyperlipidaemia and inflammation but not weight increase induced by Western diet ingestion in mice
Autor: Rasha M. Hussein
Publikováno v: Archives of Physiology and Biochemistry. :1-7
Objective This study, for the first time, investigates the effect of gum acacia (GA) on the expression of miR-33 and miR-155 and its association with the obesity and inflammation induced by Western diet (WD) consumption in mice. Methods Animals were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0b332287594983fba079fbd222e44b
https://doi.org/10.1080/13813455.2021.1876734
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7
Protective Effect of
Autor: Rasha M, Hussein, Ahmed M, Youssef, Mousa K, Magharbeh, Saed M, Al-Dalaen, Nariman A, Al-Jawabri, Taymaa N, Al-Nawaiseh, Abdullah, Al-Jwanieh, Fakhir S, Al-Ani
Publikováno v: Journal of medicinal food. 25(8)
Neuroinflammation is an adaptive immune response to the central nervous system (CNS) injury induced by infection or toxins. MicroRNAs (miRs) showed critical roles in neuroinflammation as either proinflammatory or anti-inflammatory molecules. Interest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6159d887575beafc6a561e657fea354f
https://pubmed.ncbi.nlm.nih.gov/35235435
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8
Hesperidin and eugenol attenuate cadmium-induced nephrotoxicity via regulation of oxidative stress, Bax/Bcl2 and cleaved caspase 3 expression
Autor: Marwa M. Khalaf, Rasha M. Hussein, Wafaa R. Mohamed
Publikováno v: Turkish Journal of Biochemistry. 45:767-775
Objectives Cadmium (Cd) is a heavy metal that induces nephrotoxicity through stimulating the oxidative stress in kidney cells. In this study, we investigated the protective effects of hesperidin and eugenol on Cd-induced nephrotoxicity and their impa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54df40dc21189f6d4434976ef1619cb7
https://doi.org/10.1515/tjb-2020-0161
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9
Thymol protects against bleomycin-induced pulmonary fibrosis via abrogation of oxidative stress, inflammation, and modulation of miR-29a/TGF-β and PI3K/Akt signaling in mice
Autor: Rasha M, Hussein, El-Shaimaa A, Arafa, Sayed Abdel, Raheem, Wafaa R, Mohamed
Publikováno v: Life Sciences. 314:121256
Idiopathic pulmonary fibrosis is a terminal lung ailment that shares several pathological and genetic mechanisms with severe COVID-19. Thymol (THY) is a dietary compound found in thyme species that showed therapeutic effects against various diseases.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0058921db575cc2c99135138960ab742
https://doi.org/10.1016/j.lfs.2022.121256
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10
Betaine downregulates microRNA 34a expression via a p53‐dependent manner in cisplatin‐induced nephrotoxicity in rats
Autor: Saed Mohammed Al-Dalain, Rasha M. Hussein
Publikováno v: Journal of Biochemical and Molecular Toxicology. 35
Cisplatin-induced nephrotoxicity limits its wide application as a chemotherapeutic drug. Betaine is a natural trimethylglycine compound involved in several biological reactions. In this study, the protective effect of betaine against cisplatin-induce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cb0b6011d117bb1a39ebd722a12e86
https://doi.org/10.1002/jbt.22856
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