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Emergence of gram‐negative organisms as the cause of infections in patients with sickle cell disease
Autor:
Peter G Makhoul, Nabil J. Khoury, Sara Khalife, Rachid Haidar, Ghassan Dbaibo, Rima Hanna-Wakim, Rasha I Ahmad, Miguel R. Abboud
Publikováno v:
Pediatric Blood & Cancer. 68
Background Patients with sickle cell disease are at higher risk of infections with encapsulated bacteria due to immature immune responses and functional asplenia. We aimed to study our patient population for the emergence of gram-negative organisms o
Publikováno v:
Blood. 124:4943-4943
In sickle cell disease (SCD), transfusions improve blood flow by reducing the proportion of red cells capable of forming sickle hemoglobin polymer. The major and unavoidable complication of transfusions in SCD is iron overload. Patients with signific